The biological and diagnostic role of miRNA rsquo s in hepatocellular carcinoma

10.2741/4668 ◽  
2018 ◽  
Vol 23 (9) ◽  
pp. 1701-1720 ◽  
Author(s):  
Kurt Sartorius
2020 ◽  
Vol 10 (2) ◽  
pp. 213-225
Author(s):  
Ayman El Lehleh ◽  
Nasser Abd Elbary ◽  
Reham Elzayat ◽  
Ahmed El-Gazzarah ◽  
Naglaa Elabd

2013 ◽  
Vol 99 (1) ◽  
pp. 100-107 ◽  
Author(s):  
Ashraf Khalil ◽  
Jamalat Elgedawy ◽  
Mohammed F Faramawi ◽  
Ashraf Elfert ◽  
Ibrahim Salama ◽  
...  

Aims Hepatocellular carcinoma is one of the most aggressive malignant tumors and has limited treatment options. Needle-guided biopsies have been utilized as a tool to diagnose malignant focal hepatic lesions. These techniques are discouraged because of their complications. Nowadays, alpha fetoprotein is the most widely used tumor marker for screening and diagnosis of hepatocellular carcinoma. Nevertheless, this marker has limitations. The diagnostic role of plasma osteopontin as an adjuvant or alternative marker to alpha fetoprotein to detect hepatocellular carcinoma in Egyptian patients with focal hepatic lesions was evaluated in this study. Subject and methods Eighty participants were recruited from the Egyptian National Liver Institute and were self-assigned to three groups, namely, focal hepatic lesions (n = 40), liver cirrhosis (n = 20), and controls (n = 20). Participants' plasma osteopontin and serum alpha fetoprotein levels were determined and were compared across the three groups. Results The discriminatory ability of plasma osteopontin for hepatocellular carcinoma was lower than that of alpha fetoprotein. Osteopontin and alpha fetoprotein were not correlated with each other. Neither the gender nor the age of the patients showed a significant association with plasma osteopontin level. Conclusion Measuring plasma osteopontin level alone has no advantage over serum alpha fetoprotein in patients with focal hepatic lesions due to chronic liver disease.


2016 ◽  
Vol 21 ◽  
pp. 660-667 ◽  
Author(s):  
Younghwan Kim ◽  
Yo-Han Park ◽  
Shin Hwang ◽  
Ki-Hun Kim ◽  
Chul-Soo Ahn ◽  
...  

2010 ◽  
Vol 25 (1) ◽  
pp. 129-137 ◽  
Author(s):  
Pisit Tangkijvanich ◽  
Theerawut Chanmee ◽  
Sanpoj Komtong ◽  
Varocha Mahachai ◽  
Naruemon Wisedopas ◽  
...  

2020 ◽  
Vol 52 ◽  
pp. e53
Author(s):  
G. Peserico ◽  
E. Pinto ◽  
A. Sartori ◽  
A. Imondi ◽  
F. Pelizzaro ◽  
...  

2017 ◽  
Vol 25 (10) ◽  
pp. 703-711
Author(s):  
Nanis S. Holah ◽  
Dina S. El-Azab ◽  
Hayam A.E.-S. Aiad ◽  
Dina M.M. Sweed

2014 ◽  
Vol 8 (4) ◽  
pp. 493-500 ◽  
Author(s):  
Francesco Bertagna ◽  
Mattia Bertoli ◽  
Giovanni Bosio ◽  
Giorgio Biasiotto ◽  
Ramin Sadeghi ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document