Genetic and molecular diagnostics of male infertility in the clinical practice

10.2741/4208 ◽  
2014 ◽  
Vol 19 (2) ◽  
pp. 291 ◽  
Author(s):  
Damiano Pizzol
Keyword(s):  
Clinical Practice ◽  
Male Infertility ◽  
Molecular Diagnostics

Molecular diagnostics and targeted treatment approaches in pediatric oncology (literature review)

2021 ◽  
pp. 29-33
Author(s):  
A. A. Rozhkov ◽  
R. I. Nuriev ◽  
M. I. Sekacheva
Keyword(s):  
Clinical Practice ◽  
Targeted Therapy ◽  
Side Effects ◽  
Molecular Diagnostics ◽  
New Technologies ◽  
Patient Survival ◽  
Targeted Drugs ◽  
Specific Drug ◽  
Oncological Diseases ◽  
Personalized Approach

The continuous evolution of new technologies in the field of molecular diagnostics and genome analysis, the development of new approaches in pharmacogenetics and the emergence of a range of different targeted drugs have expanded the possibilities of clinical practice, resulting in personalized approaches to treatment. The diagnosis and therapy of pediatric oncological diseases are some of the vivid examples of the successful application of a personalized approach in clinical practice. Today, many pediatric neoplastic diseases are successfully treated with targeted drugs, which significantly increases patient survival. Targeted therapy allows to choose a specific drug for each patient, thereby increasing the effectiveness of treatment, reducing the risk of side effects, and also reducing the likelihood of a relapse of the disease.

Male infertility in India: Demographics, aetiology and outcomes of standard clinical practice

2020 ◽  
Vol 33 (6) ◽  
pp. 340
Author(s):  
Rajeev Kumar ◽  
Rohit Kaushal ◽  
Nishant Gurnani ◽  
Manoj Kumar ◽  
Rima Dada
Keyword(s):  
Clinical Practice ◽  
Male Infertility ◽  
Standard Clinical Practice

scholarly journals Advances in Lymphoma Molecular Diagnostics

Diagnostics ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 2174
Author(s):  
Igor Age Kos ◽  
Lorenz Thurner ◽  
Joerg Thomas Bittenbring ◽  
Konstantinos Christofyllakis ◽  
Dominic Kaddu-Mulindwa
Keyword(s):  
Clinical Practice ◽  
Molecular Diagnostics ◽  
Genetic Alterations ◽  
Molecular Techniques ◽  
World Health ◽  
Accurate Identification ◽  
Treatment Algorithms ◽  
Lymphoid Neoplasms ◽  
Wide Range ◽  
Treatment Prognosis

Lymphomas encompass a diverse group of malignant lymphoid neoplasms. Over recent years much scientific effort has been undertaken to identify and understand molecular changes in lymphomas, resulting in a wide range of genetic alterations that have been reported across all types of lymphomas. As many of these changes are now incorporated into the World Health Organization’s defined criteria for the diagnostic evaluation of patients with lymphoid neoplasms, their accurate identification is crucial. Even if many alterations are not routinely evaluated in daily clinical practice, they may still have implications in risk stratification, treatment, prognosis or disease monitoring. Moreover, some alterations can be used for targeted treatment. Therefore, these advances in lymphoma molecular diagnostics in some cases have led to changes in treatment algorithms. Here, we give an overview of and discuss advances in molecular techniques in current clinical practice, as well as highlight some of them in a clinical context.

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