Anti-beta-glucan-like immunoprotective candidacidal antiidiotypic antibodies

Walter Magliani

doi:10.2741/3199

ANALISA KANDUNGAN BETA-GLUKAN LARUT AIR DAN LARUT ALKALI DARI TUBUH BUAH JAMUR TIRAM (Pleurotus ostreatus) DAN SHIITAKE (Lentinus edodes)

Jurnal Sains dan Teknologi Indonesia ◽

10.29122/jsti.v13i3.894 ◽

2013 ◽

Vol 13 (3) ◽

Author(s):

Netty Widyastuti ◽

Teguh Baruji ◽

Henky Isnawan ◽

Priyo Wahyudi ◽

Donowati Donowati

Keyword(s):

Molecular Structure ◽

Molecular Weight ◽

Immune System ◽

Pleurotus Ostreatus ◽

Water Soluble ◽

Low Molecular Weight ◽

Lentinus Edodes ◽

Beta Glucan ◽

Oyster Mushrooms ◽

The Difference

Beta glucan is a polysaccharide compound, generally not soluble inwater and resistant to acid. Beta glucan is used as an immunomodulator (enhancing the immune system) in mammals is usually a beta-glucan soluble in water, easily absorbed and has a low molecular weight. Several example of beta-glucan such as cellulose (β-1 ,4-glucan), lentinan (β-1 0.6-glucan) and (β-1 ,3-glucan), pleuran (β-1, 6 and β-1 ,3-glucan) are isolated from species of fungi Basidiomycota include mushrooms (Pleurotus ostreatus) and shiitake (Lentinus edodes).The purpose of thisresearch activity is to obtain beta-glucan compound that can be dissolved in water and in alkali derived from fungi Basidiomycota, i.e, Oyster mushrooms (Pleurotus ostreatus) and shiitake (Lentinus edodes). The result of beta-glucan compared to characterize the resulting beta glucan that is molecular structure . The difference of beta glucan extraction is based on the differences in solubility of beta-glucan. Beta glucan could be water soluble and insoluble water.

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Faculty Opinions recommendation of Histoplasma capsulatum alpha-(1,3)-glucan blocks innate immune recognition by the beta-glucan receptor.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1060940.521731 ◽

2007 ◽

Author(s):

Juergen Wendland

Keyword(s):

Histoplasma Capsulatum ◽

Innate Immune ◽

Immune Recognition ◽

Beta Glucan

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Faculty Opinions recommendation of Dectin-1 is required for beta-glucan recognition and control of fungal infection.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1060939.512891 ◽

2007 ◽

Author(s):

David Underhill

Keyword(s):

Fungal Infection ◽

Beta Glucan ◽

And Control

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Faculty Opinions recommendation of Dynamic, morphotype-specific Candida albicans beta-glucan exposure during infection and drug treatment.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1135900.604148 ◽

2009 ◽

Author(s):

Antonio Cassone

Keyword(s):

Candida Albicans ◽

Drug Treatment ◽

Beta Glucan

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Faculty Opinions recommendation of A beta-glucan-conjugate vaccine and anti-beta-glucan antibodies are effective against murine vaginal candidiasis as assessed by a novel in vivo imaging technique.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.12249957.13421057 ◽

2011 ◽

Author(s):

Rino Rappuoli

Keyword(s):

Conjugate Vaccine ◽

In Vivo Imaging ◽

Imaging Technique ◽

Vaginal Candidiasis ◽

Beta Glucan

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Faculty Opinions recommendation of Dose-dependent cellular and humoral responses in Galleria mellonella larvae following beta-glucan inoculation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.2755959.2419058 ◽

2010 ◽

Author(s):

Joachim Kurtz

Keyword(s):

Galleria Mellonella ◽

Beta Glucan ◽

Humoral Responses ◽

Dose Dependent

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Edible Mushrooms: Novel Medicinal Agents to Combat Metabolic Syndrome and Associated Diseases

Current Pharmaceutical Design ◽

10.2174/1381612826666200831151316 ◽

2020 ◽

Vol 26 (39) ◽

pp. 4970-4981

Author(s):

Yu-Tang Tung ◽

Chun-Hsu Pan ◽

Yi-Wen Chien ◽

Hui-Yu Huang

Keyword(s):

Metabolic Syndrome ◽

Unsaturated Fatty Acids ◽

Edible Mushroom ◽

Biologically Active ◽

Edible Mushrooms ◽

Beta Glucan ◽

Medicinal Mushrooms ◽

Associated Diseases ◽

Increased Risk

Metabolic syndrome is an aggregation of conditions and associated with an increased risk of developing diabetes, obesity and cardiovascular diseases (CVD). Edible mushrooms are widely consumed in many countries and are valuable components of the diet because of their attractive taste, aroma, and nutritional value. Medicinal mushrooms are higher fungi with additional nutraceutical attributes having low-fat content and a transisomer of unsaturated fatty acids along with high fiber content, biologically active compounds such as polysaccharides or polysaccharide β-glucans, alkaloids, steroids, polyphenols and terpenoids. In vitro experiments, animal models, and even human studies have demonstrated not only fresh edible mushroom but also mushroom extract that has great therapeutic applications in human health as they possess many properties such as antiobesity, cardioprotective and anti-diabetic effect. They are considered as the unmatched source of healthy foods and drugs. The focus of this report was to provide a concise and complete review of the novel medicinal properties of fresh or dry mushroom and extracts, fruiting body or mycelium and its extracts, fiber, polysaccharides, beta-glucan, triterpenes, fucoidan, ergothioneine from edible mushrooms that may help to prevent or treat metabolic syndrome and associated diseases.

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