Anti-CD20 Therapy and Autoimmune Disease: Therapeutic opportunities and evolving insights

10.2741/2222 ◽  
2007 ◽  
Vol 12 (1) ◽  
pp. 2194 ◽  
Author(s):  
Gregg, J. Silverman
Keyword(s):  
Autoimmune Disease ◽  
Anti Cd20

Glatiramer Acetate Complements Anti-CD20-Mediated B-Cell Depletion in Treatment of CNS Autoimmune Disease (P04.124)

Neurology ◽  
2012 ◽  
Vol 78 (Meeting Abstracts 1) ◽  
pp. P04.124-P04.124
Author(s):  
D. Hertzenberg ◽  
K. Lehmann-Horn ◽  
P. LaLive ◽  
C. Bernard ◽  
S. Zamvil ◽  
...  
Keyword(s):  
Autoimmune Disease ◽  
B Cell ◽  
Glatiramer Acetate ◽  
Cell Depletion ◽  
B Cell Depletion ◽  
Anti Cd20

scholarly journals Anti-CD20 Antibody with Multimerized Fc Domains: A Novel Strategy To Deplete B Cells and Augment Treatment of Autoimmune Disease

2015 ◽  
Vol 196 (3) ◽  
pp. 1165-1176 ◽  
Author(s):  
Xiaoyu Zhang ◽  
Henrik S. Olsen ◽  
Shaodong Chen ◽  
Edward So ◽  
Hua Zhou ◽  
...  
Keyword(s):  
B Cells ◽  
Autoimmune Disease ◽  
Cd20 Antibody ◽  
Novel Strategy ◽  
Anti Cd20

scholarly journals Mixed Cryoglobulinaemia Vasculitis Treated with Obinutuzumab in a Patient Allergic to Rituximab

2021 ◽  
Author(s):  
Margarida Gaudencio ◽  
Catarina Parente ◽  
Ana Catarina Lameiras ◽  
António Marinho
Keyword(s):  
Rheumatoid Arthritis ◽  
Systemic Lupus Erythematosus ◽  
Monoclonal Antibodies ◽  
Autoimmune Disease ◽  
Lupus Erythematosus ◽  
Cytotoxic Agents ◽  
Type Ii ◽  
Systemic Lupus ◽  
Mixed Cryoglobulinaemia ◽  
Anti Cd20

Cryoglobulinaemia is defined as the presence of cryoglobulins in the serum, which are immunoglobulins that reversibly precipitate and form a gel when the temperature is <37ºC. Autoimmune diseases such as Sjogren’s syndrome, systemic lupus erythematosus and rheumatoid arthritis could be associated with mixed cryoglobulinaemia vasculitis (MCV). The treatment of MCV generally consists of glucocorticoids, cytotoxic agents such as cyclophosphamide, plasmapheresis or anti-CD20 monoclonal antibodies including rituximab. Here, we present a case of a 60-year-old woman who developed type II MCV in the context of overlap autoimmune disease and who has been treated with a new anti-CD20 agent, obinutuzumab.

Laryngeal Manifestations of Autoimmune Diseases

2020 ◽  
Vol 5 (2) ◽  
pp. 439-456
Author(s):  
Jenny L. Pierce
Keyword(s):  
Autoimmune Disease ◽  
Autoimmune Diseases ◽  
Patient Outcomes ◽  
Correct Diagnosis ◽  
Upper Airway ◽  
Clinical Implications ◽  
Laryngeal Function ◽  
The Past ◽  
Referral Practices ◽  
Timely Referral

Purpose This review article provides an overview of autoimmune diseases and their effects on voice and laryngeal function. Method A literature review was conducted in PubMed. Combinations of the following keywords were used: “autoimmune disease and upper airway,” “larynx,” “cough,” “voice,” “dysphonia,” and “dyspnea.” Precedence was given to articles published in the past 10 years due to recent advances in this area and to review articles. Ultimately, 115 articles were included for review. Results Approximately 81 autoimmune diseases exist, with 18 of those highlighted in the literature as having laryngeal involvement. The general and laryngeal manifestations of these 18 are discussed in detail, in addition to the clinical implications for a laryngeal expert. Conclusions Voice, breathing, and cough symptoms may be an indication of underlying autoimmune disease. However, these symptoms are often similar to those in the general population. Appropriate differential diagnosis and timely referral practices maximize patient outcomes. Guidelines are provided to facilitate correct diagnosis when an autoimmune disease is suspected.

Are pharyngeal pouches a manifestation of autoimmune disease?

1998 ◽  
Vol 23 (3) ◽  
pp. 284-284
Author(s):  
Oko ◽  
Swan ◽  
Bottazzo ◽  
Collins
Keyword(s):  
Autoimmune Disease
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