Insight into molecular characterization and spectral properties of 2-methoxy-1, 4-naphthoquinone: A computational approach

2020 ◽  
Vol 61 (2) ◽  
Keyword(s):  
Molecular Characterization ◽  
Spectral Properties ◽  
Computational Approach ◽  
Insight Into

Insight into the Thiol-yne Kinetics via a Computational Approach

2021 ◽  
Author(s):  
Volkan Fındık ◽  
Betul Tuba Varinca ◽  
Isa Degirmenci ◽  
Safiye Sag Erdem
Keyword(s):  
Computational Approach ◽  
Insight Into

Fluorescent protein expression in temperature tolerant and susceptible reef-building corals

2021 ◽  
pp. 1-10
Author(s):  
Exequiel Gabriel S. Dizon ◽  
Jeric P. Da-Anoy ◽  
Melissa S. Roth ◽  
Cecilia Conaco
Keyword(s):  
Spectral Properties ◽  
Coral Species ◽  
Fluorescent Protein ◽  
Fluorescent Proteins ◽  
Expression Profiles ◽  
Expression Patterns ◽  
Antioxidant Properties ◽  
Variable Expression ◽  
Acropora Digitifera ◽  
Insight Into

Abstract Fluorescent proteins (FPs) are reported to play an important role as photoprotectants and antioxidants in corals subjected to stressful conditions. Identifying the various FP genes expressed and FP gene expression patterns under stress in diverse coral species can provide insight into FP function. In this study, we identified 16 putative FP homologues from the transcriptomes of corals with varying susceptibility to elevated temperature, including Acropora digitifera, Favites colemani, Montipora digitata and Seriatopora caliendrum. Each coral expressed a different complement of FP transcripts, which were predicted to have distinct spectral properties. The most diverse and abundant repertoire of FP transcripts, including at least 6 green FPs, were expressed in the temperature-tolerant coral, F. colemani. In comparison, the other corals expressed fewer FP types. Specific FP transcripts exhibited variable expression profiles in coral fragments subjected to 32 ± 1 °C (treatment) or 28 ± 1 °C (control) for up to 72 h, suggesting that distinct FPs may have different roles. Further studies on the expression of the proteins encoded by these FP transcripts, their fluorescence activity, tissue localization, and possible antioxidant properties, are needed to reveal their contribution to thermal stress tolerance in certain species of corals.

scholarly journals Visualising Ostia’s Processional Landscape Through a Multi-Layered Computational Approach: Case Study of the Cult of the Magna Mater

2019 ◽  
Vol 5 (1) ◽  
pp. 444-467
Author(s):  
Katherine A. Crawford
Keyword(s):  
Network Analysis ◽  
Computational Approach ◽  
Urban Network ◽  
Agent Based ◽  
Agent Based Modelling ◽  
Existing Problems ◽  
Layered Approach ◽  
Religious Landscape ◽  
Insight Into

AbstractOstia, the ancient port of Rome, had a rich religious landscape. How processional rituals further contributed to this landscape, however, has seen little consideration. This is largely due to a lack of evidence that attests to the routes taken by processional rituals. The present study aims to address existing problems in studying processions by questioning what factors motivated processional movement routes. A novel computational approach that integrates GIS, urban network analysis, and agent-based modelling is introduced. This multi-layered approach is used to question how spectators served as attractors in the creation of a processional landscape using Ostia’s Campo della Magna Mater as a case study. The analysis of these results is subsequently used to gain new insight into how a greater processional landscape was created surrounding the sanctuary of the Magna Mater.

scholarly journals Northstar enables automatic classification of known and novel cell types from tumor samples

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Fabio Zanini ◽  
Bojk A. Berghuis ◽  
Robert C. Jones ◽  
Benedetta Nicolis di Robilant ◽  
Rachel Yuan Nong ◽  
...  
Keyword(s):  
Cell Types ◽  
Neoplastic Cell ◽  
Computational Approach ◽  
Pancreatic Tumors ◽  
Published Data ◽  
Cell Type ◽  
Disease Heterogeneity ◽  
Manual Task ◽  
Insight Into

Abstract Single cell transcriptomics is revolutionising our understanding of tissue and disease heterogeneity, yet cell type identification remains a partially manual task. Published algorithms for automatic cell annotation are limited to known cell types and fail to capture novel populations, especially cancer cells. We developed northstar, a computational approach to classify thousands of cells based on published data within seconds while simultaneously identifying and highlighting new cell states such as malignancies. We tested northstar on data from glioblastoma, melanoma, and seven different healthy tissues and obtained high accuracy and robustness. We collected eleven pancreatic tumors and identified three shared and five private neoplastic cell populations, offering insight into the origins of neuroendocrine and exocrine tumors. Northstar is a useful tool to assign known and novel cell type and states in the age of cell atlases.

Molecular characterization of Plum pox virus Rec isolates from Russia suggests a new insight into evolution of the strain

Virus Genes ◽  
2018 ◽  
Vol 54 (2) ◽  
pp. 328-332 ◽  
Author(s):  
Sergei Chirkov ◽  
Peter Ivanov ◽  
Anna Sheveleva ◽  
Anna Kudryavtseva ◽  
Irina Mitrofanova
Keyword(s):  
Molecular Characterization ◽  
Plum Pox Virus ◽  
Insight Into

New insight into the molecular characterization of isoniazid and rifampicin resistant Mycobacterium tuberculosis strains from Saudi Arabia

2012 ◽  
Vol 12 (3) ◽  
pp. 549-556 ◽  
Author(s):  
Bright Varghese ◽  
Andreas Hillemann ◽  
Dian Rachma Wijayanti ◽  
Mohammed Shoukri ◽  
Fahad Al-rabiah ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Mycobacterium Tuberculosis ◽  
Molecular Characterization ◽  
Insight Into

scholarly journals Molecular Characterization of ISCR1-MediatedblaPER-1in a Non-O1, Non-O139 Vibrio cholerae Strain from China

2015 ◽  
Vol 59 (7) ◽  
pp. 4293-4295 ◽  
Author(s):  
Jun Wu ◽  
Lianyan Xie ◽  
Fangfang Zhang ◽  
Yuxing Ni ◽  
Jingyong Sun
Keyword(s):  
Vibrio Cholerae ◽  
Molecular Characterization ◽  
Cholerae Strain ◽  
Class 1 Integron ◽  
Content Type ◽  
Conserved Sequence ◽  
Circular Molecule ◽  
Class 1 ◽  
Insight Into

ABSTRACTWe report the detection of PER-1 extended-spectrum β-lactamase (ESBL) in a clinical non-O1, non-O139Vibrio choleraestrain from China. ISCR1-mediatedblaPER-1was embedded in a complex In4family class 1 integron belonging to the lineage of Tn1696on a conjugative IncA/C plasmid. A free 8.98-kb circular molecule present with the ISCR1-blaPER-1–truncated 3′-conserved sequence (CS) structure was detected in this isolate. These findings may provide insight into the mobilization ofblaPER-1.

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