Structural characterization of a Mn(II)-based coordination polymer and application of its nanoparticles for protective effect in peri-implantitis therapy by enhancing immune cell response

2020 ◽  
Vol 61 (4) ◽  
Keyword(s):  
Coordination Polymer ◽  
Protective Effect ◽  
Structural Characterization ◽  
Cell Response ◽  
Immune Cell ◽  
Immune Cell Response

scholarly journals RhoA Signaling in Immune Cell Response and Cardiac Disease

Cells ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1681
Author(s):  
Lucia Sophie Kilian ◽  
Derk Frank ◽  
Ashraf Yusuf Rangrez
Keyword(s):  
Cardiac Disease ◽  
Cell Response ◽  
Cell Activation ◽  
Immune Cell ◽  
Inflammatory Diseases ◽  
Heart Diseases ◽  
Small Gtpase ◽  
Cardiac Inflammation ◽  
Immune Cell Activation ◽  
Immune Cell Response

Chronic inflammation, the activation of immune cells and their cross-talk with cardiomyocytes in the pathogenesis and progression of heart diseases has long been overlooked. However, with the latest research developments, it is increasingly accepted that a vicious cycle exists where cardiomyocytes release cardiocrine signaling molecules that spiral down to immune cell activation and chronic state of low-level inflammation. For example, cardiocrine molecules released from injured or stressed cardiomyocytes can stimulate macrophages, dendritic cells, neutrophils and even T-cells, which then subsequently increase cardiac inflammation by co-stimulation and positive feedback loops. One of the key proteins involved in stress-mediated cardiomyocyte signal transduction is a small GTPase RhoA. Importantly, the regulation of RhoA activation is critical for effective immune cell response and is being considered as one of the potential therapeutic targets in many immune-cell-mediated inflammatory diseases. In this review we provide an update on the role of RhoA at the juncture of immune cell activation, inflammation and cardiac disease.

scholarly journals IMMU-68. SINGLE-CELL PROTEOMIC ANALYSIS OF IMMUNE CELL RESPONSE TO CHECKPOINT BLOCKADE USING 30-PARAMETER FLOW CYTOMETRY

2018 ◽  
Vol 20 (suppl_6) ◽  
pp. vi137-vi137
Author(s):  
Amber Giles ◽  
Leonard Nettey ◽  
Thomas Liechti ◽  
Margaret Beddall ◽  
Elizabeth Vera ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Single Cell ◽  
Cell Response ◽  
Proteomic Analysis ◽  
Immune Cell ◽  
Checkpoint Blockade ◽  
Immune Cell Response

scholarly journals Postoperative cellular stress in the kidney is associated with an early systemic γδ T-cell immune cell response

Critical Care ◽  
2018 ◽  
Vol 22 (1) ◽  
Author(s):  
Ivan Göcze ◽  
Katharina Ehehalt ◽  
Florian Zeman ◽  
Paloma Riquelme ◽  
Karin Pfister ◽  
...  
Keyword(s):  
T Cell ◽  
Cell Response ◽  
Immune Cell ◽  
Cellular Stress ◽  
Γδ T Cell ◽  
Immune Cell Response

scholarly journals Synthesis and structural characterization of a single-crystal to single-crystal transformable coordination polymer

2014 ◽  
Vol 43 (4) ◽  
pp. 1519-1523 ◽  
Author(s):  
Yuyang Tian ◽  
Phoebe K. Allan ◽  
Catherine L. Renouf ◽  
Xiang He ◽  
Laura J. McCormick ◽  
...  
Keyword(s):  
Coordination Polymer ◽  
Single Crystal ◽  
Structural Characterization

scholarly journals Synthesis and structural characterization of transition metal dithiolene derivatives containing divalent metals as counter-cations

CrystEngComm ◽  
2019 ◽  
Vol 21 (9) ◽  
pp. 1423-1432 ◽  
Author(s):  
Oscar Castillo ◽  
Esther Delgado ◽  
Diego Hernández ◽  
Elisa Hernández ◽  
Avelino Martín ◽  
...  
Keyword(s):  
Coordination Polymer ◽  
Transition Metal ◽  
Structural Characterization ◽  
Metal Cations ◽  
Magnetic Behaviour ◽  
Divalent Metal ◽  
Divalent Metals ◽  
Divalent Metal Cations ◽  
1D Coordination Polymer

Complexes containing [Fe2(SC6H2Cl2S)4]2− or [Ni(SC6H2Cl2S)2]− entities and divalent metal cations as well as an 1D-coordination polymer K/Zn have been obtained and their magnetic behaviour studied.

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