scholarly journals In situ characterization of B-and T-lymphocytes in basal cell carcinoma of the head and neck region

1997 ◽  
Vol 3 (1) ◽  
pp. 58-67
Author(s):  
S. M. A. Saleh ◽  
A. A. El Sissy ◽  
E. M. Ismail
Keyword(s):  
T Cells ◽  
T Lymphocytes ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Basal Cell ◽  
Neck Region ◽  
Lymphocytic Infiltrate ◽  
Head And Neck Region ◽  
Humoral Immune

Twentycases of basal cell carcinoma [BCC] of the head and neck region were examined immunohistochemically for the detection of T- and Blymphocytes. The results showed that the dense lymphocytic infiltrate surrounding neoplastic cells of BCC consisted chiefly of T-lymphocytes. The lymphocytic infiltrate revealed in parts a pattern of a small lymphocytic follicle with peripherally situated T cells and central B cells. The predominance of Tlymphocytes in BCC suggests a local cell-mediated immune response. However, the presence of B-lymphocytes indicates a possible humoral immune reaction. T cells may be responsible for regulating the proliferation, and thus the growth, of malignant epithelial cells in BCC

scholarly journals Incomplete excision of basal cell carcinoma (BCC) in the head and neck region: to wait, or not to wait?

2017 ◽  
Vol 34 (6) ◽  
pp. 607-611 ◽  
Author(s):  
Jakub Miszczyk ◽  
Michał Charytonowicz ◽  
Tomasz Dębski ◽  
Bartłomiej Noszczyk
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Basal Cell ◽  
Neck Region ◽  
Head And Neck Region ◽  
Incomplete Excision

Occurrence and recurrence of basal cell carcinoma of the head and neck in negroid and albinoid africans

1987 ◽  
Vol 101 (12) ◽  
pp. 1324-1328 ◽  
Author(s):  
S. A. Ademiluyi ◽  
G. T. A. Ijaduola
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Recurrence Rate ◽  
Basal Cell ◽  
Neck Region ◽  
Head And Neck Region ◽  
Outdoor Workers ◽  
Significant Difference

SummaryA study of sixty patients with basal cell carcinoma of the head and neck region carried out over a six-year period (1979–1985) is hereby presented. Sixteen (26.72 percent) were albinos and 44 (73.28 per cent) negroids. Forty-eight (80 per cent) were outdoor workers. The negroid patients presented between the 3rd and 4th decades while the albinos presented a decade earlier. The commonest site involved in the head and neck was the forehead. The midface showed the highest recurrence rate in both groups, even after adequate excision. The frequency of recurrence in tumours presenting with a size of 2–5 cm. diameter was significantly higher in the albinos than in the negroid (P<0.05), whereas, with tumours of a size larger than 5 cm., there was no statistically significant difference between the albino and the negroid. However, the overall recurrence rate was significantly higher in the albinos (P<0.005). The mortality among the albinos was 25 per cent while there were no deaths in the negroid Africans.

scholarly journals Basal Cell Carcinoma of the Head and Neck Region: An Analysis of 171 Cases

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Omer Sefvan Janjua ◽  
Sana Mehmood Qureshi
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Basal Cell ◽  
Neck Region ◽  
Margin Status ◽  
Anatomical Site ◽  
Female Ratio ◽  
Head And Neck Region ◽  
Malignant Skin Tumors

Objective. To analyze the pattern of presentation of basal cell carcinoma (BCC) and margin status for excised specimens in the head and neck region.Study Design. Retrospective cross-sectional.Duration of Study.January 2009 to December 2011.Methodology. The database of the pathology department was searched to identify records of all malignant skin tumors that underwent standard excision with margins. Out of these records, tumors with a diagnosis of BCC in the head and neck region were retrieved and separated. Age, gender, anatomic location, pattern of tumor, and margin status were noted.Results. A total of 171 cases of BCC from various sites of head and neck were retrieved. Male to female ratio was 1.4 : 1. The age ranged from 22 to 90 years. Seventy-six cases presented on right side, 79 on left, and 16 were in the midline. Most common anatomical site was the nose followed by the cheek. Nodular lesions were the most common (46.2%) followed by pigmented variety (18.7%). Margins were clear in 77 (45.1%) cases, involved in 86 (50.2%) cases, and close in 8 (4.7%) cases.Conclusion. Nose was the most common site followed by the cheek. Nodular and pigmented varieties were the most frequent and margins were involved in more than fifty percent of the cases.

Treatment of Basal Cell Carcinoma Located in the Head and Neck Region with Intralesional Interferon ??-2a

2005 ◽  
Vol 25 (10) ◽  
pp. 661-667 ◽  
Author(s):  
Seher Bostanci ◽  
Pelin Kocyigit ◽  
Ay??eg??l Alp ◽  
Cengizhan Erdem ◽  
Erbak G??rgey
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Basal Cell ◽  
Neck Region ◽  
Head And Neck Region

scholarly journals Giant Ulcerative Dermatofibroma

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Turgut Karlidag ◽  
Erol Keles ◽  
Israfil Orhan ◽  
Mehmet Erkan Kaplama ◽  
Bengu Cobanoglu
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Basal Cell ◽  
Neck Region ◽  
Dermatofibrosarcoma Protuberans ◽  
Epidermoid Carcinoma ◽  
Head And Neck Region ◽  
Cutaneous Tumor

Dermatofibroma is a slowly growing common benign cutaneous tumor characterized by hard papules and nodules. The rarely seen erosions and ulcerations may cause difficulties in the diagnosis. Dermatofibrosarcoma protuberans, which is clinically and histopathologically of malignant character, displays difficulties in the diagnosis since it has similarities with basal cell carcinoma, epidermoid carcinoma, and sarcomas. Head and neck involvement is very rare. In this study, a giant dermatofibroma case, which is histopathologically, ulcerative dermatofibroma, the biggest lesion of the head and neck region and seen rarely in the literature that has characteristics similar to dermatofibrosarcoma protuberans, has been presented.

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