scholarly journals Pattern of growth and development of premature children at the age of two and three years in Alexandria, Egypt [Part I]

2021 ◽  
Vol 1 (2) ◽  
pp. 176-185
Author(s):  
Khadiga, A. Khalil ◽  
Shahira M. El Amrawy ◽  
Afaf G. Ibrahim ◽  
Nadia A. El Zeiny ◽  
Azza E. Greiw
Keyword(s):  
Growth And Development ◽  
Case Control Study ◽  
Case Control ◽  
Full Term ◽  
Fine Motor ◽  
Premature Children ◽  
Quality Medical Care ◽  
Control Study ◽  
Age And Sex ◽  
Better Than

A case-control study was conducted in Alexandria on 68 premature children:32 of them at the age of 2 and 36 at the age of three years. The aim was to depict the pattern of growth and development among them. Controls were full-term children, who were double the number of prematures and matched by age and sex. It was found that the growth pattern of full-term children aged two and three years was better than that of prematures. Moreover, prematures were significantly delayed in some developmental areas as language, fine motor-adaptive sectors and personal-social domains than their corresponding controls. The study suggests that the provision of quality medical care could eliminate the growth and developmental lag of premature children

scholarly journals Genetic association of TOLLIP gene polymorphisms and HIV infection: a case-control study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ming-Gui Wang ◽  
Jing Wang ◽  
Jian-Qing He
Keyword(s):  
Hiv Infection ◽  
Gene Polymorphisms ◽  
Case Control Study ◽  
Binary Logistic Regression ◽  
Case Control ◽  
Additive Models ◽  
Chinese Han ◽  
Interacting Protein ◽  
Control Study ◽  
Age And Sex

Abstract Background Previous studies have indicated that host genetic factors play an essential role in immunity to human immunodeficiency virus (HIV) infection. We aimed to investigate the association between the toll-interacting protein (TOLLIP) and mannose-binding lectin 2 (MBL2) genes and HIV infection susceptibility among Chinese Han patients. Methods This is a case-control study. A total of 435 HIV-infected patients and 1013 seronegative healthy individuals were recruited. DNA was extracted from whole blood. Two SNPs in the MBL2 gene (rs7096206 and rs1800450) and three SNPs in the TOLLIP gene (rs5743899, rs3750920, and rs5743867) were selected and genotyped using a SNPscan Kit (Cat#: G0104, Genesky Biotechnologies Inc., Shanghai, China). Odds ratios (ORs) and their 95% confidence intervals (CIs) were calculated using unconditional binary logistic regression. Results A significant association between the minor alleles rs5743899 (C allele) and rs5743867 (G allele) in the TOLLIP gene and susceptibility to HIV infection was found in this study after adjusting for age and sex (Pa = 0.011 and < 0.001, respectively). The rs5743867 in the TOLLIP gene was significantly associated with the risk of HIV infection in dominant, recessive, and additive models when adjusted for age and sex (Pa < 0.05). No significant association was found between MBL2 gene polymorphisms and HIV infection. Conclusion Our study found a statistically significant association between the two SNPs (rs5743867 and rs5743899) in the TOLLIP gene and susceptibility to HIV infection in a Chinese Han population.

To evaluate the role of placental human papilloma virus (HPV) infection as a risk factor for spontaneous preterm birth: a prospective case control study

2022 ◽  
Vol 0 (0) ◽  
Author(s):  
Reetu Hooda ◽  
Neeru Baghla ◽  
Nisha Malik ◽  
Samander Kaushik
Keyword(s):  
Case Control Study ◽  
Perinatal Outcomes ◽  
Preterm Births ◽  
Placental Tissue ◽  
Hpv Infection ◽  
Case Control ◽  
Full Term ◽  
Hpv 16 ◽  
Papilloma Virus ◽  
Control Study

Abstract Objectives i) To compare the placental human papilloma virus (HPV) deoxynucleic acid (DNA) status of preterm deliveries with full term deliveries and to identify high risk (HR) genotypes (HPV 16 and 18); and ii) To compare the perinatal outcomes of HPV positive with HPV negative pregnant women. Methods A case control study was carried out on 100 antenatal women with singleton live pregnancies admitted in labor ward of a tertiary care teaching hospital from April 2017 to March 2018. The two study groups were i) spontaneous preterm deliveries between 24 and 36 + 6 weeks (n=50) and ii) full term deliveries ≥37 weeks (n=50). The placental tissue was analysed for HPV DNA and HR HPV genotypes were detected by type specific primers. A comparative analysis of perinatal outcomes between HPV positive and negative women was done. Results An overall placental tissue HPV prevalence of 12% (12/100) was observed in study cohort which was not significantly different between preterm and full term deliveries (16 vs. 8%, p=0.218). HPV 16 was significantly associated with preterm births (p=0.04). Both HPV affected and non-affected women were comparable in terms of mode of delivery and neonatal outcomes. However, a statistically significant association of preterm neonatal intensive care admissions with HR HPV 16 genotype was observed (p=0.04). Conclusions Spontaneous preterm births can be attributed to placental HPV infection, specifically HR HPV 16 genotype. This association identifies a potentially preventable cause of prematurity and its associated complications, in wake of availability of an effective vaccine.

Consumption of uncooked deer meat as a risk factor for hepatitis E virus infection: An age- and sex-matched case-control study

2004 ◽  
Vol 74 (1) ◽  
pp. 67-70 ◽  
Author(s):  
Shuchin Tei ◽  
Naoto Kitajima ◽  
Shunji Ohara ◽  
Yoshifumi Inoue ◽  
Masaharu Miki ◽  
...  
Keyword(s):  
Risk Factor ◽  
Virus Infection ◽  
Hepatitis E Virus ◽  
Case Control Study ◽  
Hepatitis E ◽  
Case Control ◽  
Matched Case ◽  
Matched Case Control Study ◽  
Control Study ◽  
Age And Sex

Negative Interaction between Lithium and Electroconvulsive Therapy – A Case-Control Study

1996 ◽  
Vol 168 (2) ◽  
pp. 241-243 ◽  
Author(s):  
A. K. Jha ◽  
G. S. Stein ◽  
P. Fenwick
Keyword(s):  
Adverse Effects ◽  
Case Control Study ◽  
Case Control ◽  
Control Group ◽  
Study Group ◽  
Negative Interaction ◽  
Retrospective Case ◽  
Concurrent Use ◽  
Control Study ◽  
Age And Sex

BackgroundConcurrent use of lithium and ECT is suspected to increase neurotoxicity.MethodA retrospective case-control study over an eight-year period was conducted to investigate the adverse effects of a combined lithium/ECT treatment Thirty-one subjects with combined lithium/ECT treatment were compared with a control group (ECT only) of 135 cases matched for age and sex.ResultsMost cases in both groups had no adverse effects. Three (10%) study group subjects and 15 (11 %) controls experienced brief delirium. Three controls and none of the subjects developed a prolonged confusion. There were no significant differences in the profile of other adverse effects between the two groups.ConclusionPrescription of lithium together with ECT was not associated with higher frequency of adverse effects.

scholarly journals Risk factors for post-bronchoscopy pneumonia: a case–control study

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Yu Sato ◽  
Kengo Murata ◽  
Miake Yamamoto ◽  
Tsukasa Ishiwata ◽  
Miyako Kitazono-Saitoh ◽  
...  
Keyword(s):  
Risk Factors ◽  
Multivariate Analysis ◽  
Risk Factor ◽  
Independent Risk Factor ◽  
Case Control Study ◽  
Case Control ◽  
Control Group ◽  
Tracheobronchial Stenosis ◽  
Control Study ◽  
Age And Sex

AbstractThe bronchoscopy, though usually safe, is occasionally associated with complications, such as pneumonia. However, the use of prophylactic antibiotics is not recommended by the guidelines of the British Thoracic Society. Thus far there are few reports of the risk factors for post-bronchoscopy pneumonia; the purpose of this study was to evaluate these risk factors. We retrospectively collected data on patients in whom post-bronchoscopy pneumonia developed from the medical records of 2,265 patients who received 2666 diagnostic bronchoscopies at our institution between April 2006 and November 2011. Twice as many patients were enrolled in the control group as in the pneumonia group. The patients were matched for age and sex. In total, 37 patients (1.4%) had post-bronchoscopy pneumonia. Univariate analysis showed that a significantly larger proportion of patients in the pneumonia group had tracheobronchial stenosis (75.7% vs 18.9%, p < 0.01) and a final diagnosis of primary lung cancer (75.7% vs 43.2%, p < 0.01) than in the control group. The pneumonia group tended to have more patients with a history of smoking (83.8% vs 67.1%, p = 0.06) or bronchoalveolar lavage (BAL) (4.3% vs 14.9%, p = 0.14) than the control group. In multivariate analysis, we found that tracheobronchial stenosis remained an independent risk factor for post-bronchoscopy pneumonia (odds ratio: 7.8, 95%CI: 2.5–24.2). In conclusion, tracheobronchial stenosis was identified as an independent risk factor for post-bronchoscopy pneumonia by multivariate analysis in this age- and sex- matched case control study.

scholarly journals Short stems reproduce femoral offset better than standard stems in total hip arthroplasty: a case-control study

2019 ◽  
Vol 44 (1) ◽  
pp. 45-51 ◽  
Author(s):  
Roger Erivan ◽  
Anne-Sophie Muller ◽  
Guillaume Villatte ◽  
Stéphane Millerioux ◽  
Aurélien Mulliez ◽  
...  
Keyword(s):  
Total Hip Arthroplasty ◽  
Hip Arthroplasty ◽  
Case Control Study ◽  
Case Control ◽  
Femoral Offset ◽  
Total Hip ◽  
Short Stems ◽  
Control Study ◽  
Better Than

Migraine and Left-Handedness are not Associated. A New Case—Control Study and Meta-Analysis

Cephalalgia ◽  
2008 ◽  
Vol 28 (5) ◽  
pp. 553-557 ◽  
Author(s):  
K Biehl ◽  
A Frese ◽  
M Marziniak ◽  
I-W Husstedt ◽  
S Evers
Keyword(s):  
Diagnostic Criteria ◽  
Case Control Study ◽  
Matched Control ◽  
International Headache Society ◽  
Meta Analysis ◽  
Case Control ◽  
Left Handedness ◽  
Significant Difference ◽  
Control Study ◽  
Age And Sex

To investigate the possible association between migraine and left-handedness, we enrolled 100 patients with a diagnosis of migraine according to the International Headache Society diagnostic criteria and 100 age- and sex-matched control subjects into a case—control study. Handedness was determined by the Edinburgh Handedness Inventory. There was no significant difference in the frequency or grade of left-handedness between the two groups. Additionally, we pooled our data with those from five similar studies, which did not alter the result. Thus, neither our study nor the meta-analysis support Geschwind and Behan's hypothesis of an association between migraine and left-handedness.

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