scholarly journals The assessment of new bone formation induced by unfocused extracorporeal shock wave therapy applied on pre-surgical phase of distraction osteogenesis

2019 ◽  
pp. 125-131
Author(s):  
Erman Senel ◽  
Enes Ozkan ◽  
Mehmet Cihan Bereket ◽  
Mehmet Emin Gungor
Keyword(s):  
Shock Wave ◽  
Bone Formation ◽  
Distraction Osteogenesis ◽  
Extracorporeal Shock Wave Therapy ◽  
New Bone Formation ◽  
Shock Wave Therapy ◽  
Extracorporeal Shock Wave

Effects of Extracorporeal Shock Wave Therapy on Distraction Osteogenesis in Rat Mandible

2018 ◽  
Vol 142 (6) ◽  
pp. 1501-1509 ◽  
Author(s):  
Jiriys G. Ginini ◽  
Gila Maor ◽  
Omri Emodi ◽  
Dekel Shilo ◽  
Yankel Gabet ◽  
...  
Keyword(s):  
Shock Wave ◽  
Distraction Osteogenesis ◽  
Extracorporeal Shock Wave Therapy ◽  
Shock Wave Therapy ◽  
Extracorporeal Shock Wave ◽  
Rat Mandible

scholarly journals Extracorporeal Shock Wave Therapy Promotes Osteogenic Differentiation in a Rabbit Osteoporosis Model

2021 ◽  
Vol 12 ◽  
Author(s):  
Baofeng Li ◽  
Renkai Wang ◽  
Xianyin Huang ◽  
Yongliang Ou ◽  
Zhenyu Jia ◽  
...  
Keyword(s):  
Shock Wave ◽  
Bone Formation ◽  
Osteogenic Differentiation ◽  
Extracorporeal Shock Wave Therapy ◽  
Shock Wave Therapy ◽  
Detailed Mechanism ◽  
Extracorporeal Shock Wave ◽  
Osteoblast Maturation

Extracorporeal shock wave therapy (ESWT) has been identified to accelerate bone formation. However, detailed mechanism has not been fully explained. In this study, we found that ESWT promoted osteoblast formation in vitro. Local ESW treatment of femur increased bone formation in vivo. Furthermore, changing the density or frequency of energy, there was no statistical difference in osteogenic differentiation. Therapeutically, local ESW therapy relieved bone loss and increased the number of bone trabecular in a rabbit osteoporosis model and promoted endogenous levels of SMAD2 protein expression. Thus, ESWT may be a potential therapy by promoting osteoblast maturation through TGF-β/SMAD2 pathway.

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