Influence of glycaemic control on platelet count in type II diabetics in absence of vascular complications

2017 ◽  
Vol 5 (2) ◽  
pp. 22-24
Author(s):  
Kazi Husna Abdul Naeem ◽  
Mohammed Abdul Hannan Hazari ◽  
Farisa Khatoon ◽  
Farah Bahmed ◽  
Fariha Mohammedi
Keyword(s):  
Platelet Count ◽  
Glycaemic Control ◽  
Vascular Complications ◽  
Type Ii ◽  
Type Ii Diabetics

Sense of coherence and glycaemic control among a sample of newly diagnosed type II diabetics in rural Crete

2017 ◽  
Author(s):  
Dimitrios Anyfantakis ◽  
Anastasios Anyfantakis ◽  
Michaela Foukaki ◽  
Serafim Kastanakis
Keyword(s):  
Glycaemic Control ◽  
Sense Of Coherence ◽  
Type Ii ◽  
Newly Diagnosed ◽  
Type Ii Diabetics

Role of hyperglucagonemia in maintenance of increased rates of hepatic glucose output in type II diabetics

Diabetes ◽  
1987 ◽  
Vol 36 (3) ◽  
pp. 274-283 ◽  
Author(s):  
A. D. Baron ◽  
L. Schaeffer ◽  
P. Shragg ◽  
O. G. Kolterman
Keyword(s):  
Type Ii ◽  
Hepatic Glucose Output ◽  
Hepatic Glucose ◽  
Type Ii Diabetics ◽  
Glucose Output

Apolipoprotein E polymorphism and hyperlipemia in type II diabetics

Diabetes ◽  
1986 ◽  
Vol 35 (12) ◽  
pp. 1374-1382 ◽  
Author(s):  
M. Eto ◽  
K. Watanabe ◽  
Y. Iwashima ◽  
A. Morikawa ◽  
E. Oshima ◽  
...  
Keyword(s):  
Apolipoprotein E ◽  
Type Ii ◽  
Apolipoprotein E Polymorphism ◽  
Type Ii Diabetics

scholarly journals Correlation of blood counts with vascular complications in essential thrombocythemia: analysis of the prospective PT1 cohort

Blood ◽  
2012 ◽  
Vol 120 (7) ◽  
pp. 1409-1411 ◽  
Author(s):  
Peter J. Campbell ◽  
Cathy MacLean ◽  
Philip A. Beer ◽  
Georgina Buck ◽  
Keith Wheatley ◽  
...  
Keyword(s):  
Platelet Count ◽  
Essential Thrombocythemia ◽  
Myeloproliferative Neoplasm ◽  
Vascular Complications ◽  
Complication Rates ◽  
Normal Range ◽  
Major Hemorrhage ◽  
Confounding Variables ◽  
Wbc Count

Abstract Essential thrombocythemia, a myeloproliferative neoplasm, is associated with increased platelet count and risk of thrombosis or hemorrhage. Cytoreductive therapy aims to normalize platelet counts despite there being only a minimal association between platelet count and complication rates. Evidence is increasing for a correlation between WBC count and thrombosis, but prospective data are lacking. In the present study, we investigated the relationship between vascular complications and 21 887 longitudinal blood counts in a prospective, multicenter cohort of 776 essential thrombocythemia patients. After correction for confounding variables, no association was seen between blood counts at diagnosis and future complications. However, platelet count outside of the normal range during follow-up was associated with an immediate risk of major hemorrhage (P = .0005) but not thrombosis (P = .7). Elevated WBC count during follow-up was correlated with thrombosis (P = .05) and major hemorrhage (P = .01). These data imply that the aim of cytoreduction in essential thrombocythemia should be to keep the platelet count, and arguably the WBC count, within the normal range. This study is registered at the International Standard Randomized Controlled Trials Number Registry (www.isrctn.org) as number 72251782.

scholarly journals A Pilot Study Investigating the effect of Glycemic Control on Electrodiagnostic Parameters in Type II Diabetic Patients

2021 ◽  
pp. 146-153
Author(s):  
Parikshit Ashok Muley ◽  
Dalia A. Biswas ◽  
Avinash Taksande
Keyword(s):  
Risk Factor ◽  
Pilot Study ◽  
Glycemic Control ◽  
Glycaemic Control ◽  
Independent Risk Factor ◽  
Diabetic Patients ◽  
Type Ii ◽  
Duration Of Diabetes ◽  
Group Number

Background: Diabetes is a chronic metabolic abnormality due to either decreased secretion of insulin or decreased tissue sensitivity of insulin resulting in elevated blood glucose. Most common complication of diabetes is peripheral neuropathy. In this research project, we will be conducting a pilot study to observe the effect of glycaemic control on physiological functioning of nerve with the help of neurophysiological parameters, independent of duration of diabetes. Objectives: To investigate relationship of quality of glycemic control & severity of neurological changes. To find out whether glycemic control acts as an independent risk factor for progression of diabetic neuropathy despite the duration of diabetes. To validate the HBA1C at 10 for future longitudinal study to understand the association between glycemic control & progression of neuropathy. Methodology: 60 type II diabetic patients visiting diabetic OPD (Medicine) will participate in the study. The patients will be divided in to 2 groups of Group number 1 with (30 subjects) HBA1C < 10 and Group number 2 having (30 subjects) HBA1C >10. Electrodiagnostic study will be conducted on motor (tibial nerve) and sensory (sural nerve) will be performed in Neurophysiology lab. Neurophysiological parameters data of two groups will be analysed and compared. Expected Results: The pilot study will help to find out whether glycaemic control acts as a separate risk factor for progression of diabetic neuropathy despite duration of diabetes. Conclusion: This pilot study will help to establish the association between quality of glycaemic control and severity of neurological changes. Also, this will help to validate the HBA1C at 10 for further longitudinal study to know whether poor diabetes control is an independent risk factor associated to the severity of neuropathy in type II diabetes.

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