Metabolic syndrome and uric acid levels - A cross sectional study

2019 ◽  
Vol 9 (1) ◽  
pp. 09-12
Author(s):  
Shamsheer Khan P ◽  
◽  
Senthil Kumar S ◽  
A Nasreen Begum ◽  
M Ramasubba Reddy ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Uric Acid ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Evaluation of Lipid Peroxidation and Antioxidants’ Status in Metabolic Syndrome

2012 ◽  
Vol 8 (4) ◽  
pp. 382-386 ◽  
Author(s):  
S Shrestha ◽  
L Chandra ◽  
M Aryal ◽  
B K L Das ◽  
S Pandey ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Metabolic Syndrome ◽  
Uric Acid ◽  
Cardiovascular Diseases ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Health Sciences ◽  
Sectional Study ◽  
Cross Sectional ◽  
Staff Members

Background Metabolic syndrome is a constellation of physical conditions and metabolic abnormalities, commonly occurring together, that increases an individual’s risk for development of type 2 diabetes mellitus and cardiovascular diseases. Oxidative stress is associated with diabetes, hypertension and other cardiovascular diseases while the role of oxidative stress in pathogenesis of MS is not clearlydefined. Objectives The study aims to find out the prevalence of metabolic syndrome in faculty and staff members at BP Koirala Institute of Health Sciences, Dharan, Nepal and to evaluate oxidative stress levels insubjects with metabolic syndrome. Methods 118 healthy participants working at B. P. Koirala Institute of Health Sciences, Dharan, Nepal were selected at random for this cross-sectional study and blood samples were collected for the estimation of the following biochemical analytes; fasting glucose; triglycerides; total cholesterol; high density lipoprotein cholesterol; Albumin; uric acid; Bilirubin; Malondialdehyde; Catalase; Glutathione peroxidase; Superoxide Dismutase; Glutathione; vitamin C; and lastly vitamin E. Results In this cross-sectional study, 39% subjects were diagnosed with metabolic syndrome , particularly in sedentary subjects. There was no difference in oxidative stress except significant rises in serum uric acid levels and catalase activity in subjects diagnosed with metabolic syndrome . Conclusion The prevalence of metabolic syndrome is higher without oxidative stress in this study, which suggests that oxidative stress does not contribute to the pathogenesis of MS in otherwise healthy subjects.http://dx.doi.org/10.3126/kumj.v8i4.6236 Kathmandu Univ Med J 2010;8(4):382-6   

scholarly journals The effect of hepcidin on components of metabolic syndrome in chronic kidney disease: a cross-sectional study

2020 ◽  
Vol 66 (8) ◽  
pp. 1100-1107
Author(s):  
Sibel Gökçay Bek ◽  
Berna Üstüner ◽  
Necmi Eren ◽  
Zeynep Sentürk ◽  
Betül Kalender Gönüllü
Keyword(s):  
Metabolic Syndrome ◽  
Chronic Kidney Disease ◽  
Uric Acid ◽  
Kidney Disease ◽  
Cross Sectional Study ◽  
Renal Diseases ◽  
Sectional Study ◽  
C Reactive Protein ◽  
Cross Sectional ◽  
Reactive Protein

SUMMARY BACKGROUND Hepcidin is an important regulator of iron homeostasis. OBJECTIVES This cross-sectional study was conducted to evaluate the association between hepcidin and components of metabolic syndrome in patients with chronic kidney disease (CKD). DESIGN AND SETTING 103 CKD patients and 59 healthy volunteers were included in the study from the University Hospital. METHODS Serum hepcidin levels were measured by enyzme-linked immunosorbent assay (ELISA) test. As for the study parameters, age, sex, body mass index, renal diseases, serum biochemistry, complete blood count, iron and total iron-binding capacity, ferritin, high-sensitive C-reactive protein (hsCRP), C- reactive protein (CRP), and erythrocyte sedimentation rate (ESR) were evaluated. RESULTS The mean age of the patients was 58.63 ± 11.8 years. Hepcidin level was significantly associated with hypertension and higher uric acid levels (P < 0.05). There was a positive correlation between hepcidin and urea, uric acid, creatinine, ferritin, CRP, ESR, phosphorus, triglyceride, low-density lipoprotein (LDL), proteinuria and albuminuria in 24-hour urine collection. A negative correlation was found between hepcidin and estimated glomerular filtration rate (eGFR), hemoglobin, hematocrit, calcium, 25 OH vitamin D, pH, and bicarbonate levels. CONCLUSION Hepcidin, a well-known hormone regulator of iron metabolism, may play an important role in the pathogenesis of metabolic syndrome in patients with CKD, and further studies might delineate in-depth its potential as a promising early marker in these patients.

Hyperhomocysteinemia in association with male gender, advanced age, uric acid and metabolic syndrome: A retrospective cross-sectional study

2019 ◽  
Author(s):  
Po-Ju Chen ◽  
Yueh-Chien Lu ◽  
Pei-Ming Wang ◽  
Song-Seng Loke
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Logistic Regression ◽  
Uric Acid ◽  
Cross Sectional Study ◽  
Male Gender ◽  
Advanced Age ◽  
Stepwise Logistic Regression ◽  
Sectional Study ◽  
Cross Sectional

Abstract Background Elevated homocysteine level has been proposed as a risk factor for cardiovascular disease. The aim of this study is to evaluate the connection between hyperhomocysteinemia with other factors for early detection of possible cardiovascular disease. Methods The data in this retrospectively designed cross-sectional study was retrieved from the health examination database in a medical center located in southern Taiwan in 2016. The correlation of hyperhomocysteinemia with sex, age, body mass index, waist circumference, lipid profile, blood pressure, uric acid, high sensitivity C-reactive protein and lipoprotein were investigated. Both simple and multiple stepwise logistic regression models were used for the assessment of their connection. Results A total of 878 subjects with mean age of 55.4 ± 10.8 years were included in the current study and 73 (9.1%) participants had elevated homocysteine levels. Simple logistic regression analysis showed elevated Hcy was significantly associated with sex (OR 0.11, 95% CI 0.04-0.31, P < 0.001), age (OR 1.03, 95% CI 1.00-1.05, P < 0.035), waist circumference (OR 1.04, 95% CI 1.02-1.06, P = 0.001), HDL-C (OR 0.97, CI 0.95-0.99, P = 0.011), triglyceride (OR 1.00, CI 1.00-1.01, P = 0.002), SBP (OR 1.02, CI 1.01-1.03, P = 0.004), DBP (OR 1.04, CI 1.02-1.06, P = 0.001), sugar level (OR 1.01, CI 1.00-1.02, P = 0.021), uric acid (OR 1.39, CI 1.20-1.60, P < 0.001) and the presence of metabolic syndrome (OR 1.81, CI 1.12-2.93, P = 0.016). Multiple stepwise logistic regression analysis was applied and the result showed that male gender (OR 0.15, 95% CI 0.05-0.43, P < 0.001), advanced age (OR 1.03, 95% CI 1.00-1.05, P < 0.036), triglycerides (OR 1.002, 95% CI 1.001-1.004, P = 0.022), systolic blood pressure (OR 1.02, 95% CI 1.00-1.03, P = 0.023) and uric acid (OR 1.26, 95% CI 1.07-1.47, P = 0.005) were significantly associated with the elevation of plasma homocysteine. Conclusions Several factors are associated with hyperhomocysteinemia in asymptomatic subjects including sex, age, uric acid and metabolic syndrome components. Among these factors, male, advanced age, systolic blood pressure, plasma level of triglyceride and uric acid were independently associated with hyperhomocysteinemia.

scholarly journals Association of Adherence to The Mediterranean Diet with Urinary Factors Favoring Renal Lithiasis: Cross-Sectional Study of Overweight Individuals with Metabolic Syndrome

Nutrients ◽  
2019 ◽  
Vol 11 (8) ◽  
pp. 1708
Author(s):  
Prieto ◽  
Rodriguez ◽  
Sanchis ◽  
Morey ◽  
Fiol ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Uric Acid ◽  
Calcium Salt ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
High Adherence ◽  
Crystallization Risk ◽  
Urinary Parameters ◽  
Urinary Crystallization

Our purpose was to study the relationship of adherence to the Mediterranean diet (MedDiet) with urinary factors that favor the formation of renal calcium and uric acid stones in overweight and obese participants who had metabolic syndrome. This cross-sectional study examined 267 participants. A well-known MedDiet score (range 0–9) was calculated for each patient, and patients were then categorized has having low (≤3), medium (4–5), or high (≥6) adherence to the MedDiet. Baseline characteristics and urinary parameters were also analyzed. High calcium salt urinary crystallization risk (CaUCR) and high uric acid urinary crystallization risk (UrUCR) were calculated from urinary parameters using pre-defined criteria. More than half of patients with MedDiet scores ≤3 had high UrUCR (55.4%) and high CaUCR (53.8%). In contrast, fewer patients with high adherence (≥6) to the MedDiet had high UrUCR (41.2%) and high CaUCR (29.4%). Relative to those with low adherence, individuals with high adherence had a prevalence ratio (PR) of 0.77 for a high UrUCR (95% CI: 0.46–1.12; p for trend: 0.069) and a PR of 0.51 for a high CaUCR (95% CI: 0.26–0.87; p for trend: 0.012) after adjusting for age, sex, body mass index, type 2 diabetes, and total energy intake. Our findings indicate that greater adherence to the MedDiet was associated with a reduced CaUCR and a reduced UrUCR. This suggests that adequate dietary management using the MedDiet patterns may prevent or reduce the incidence and recurrence of calcium salt and uric acid renal stones.

scholarly journals Association between Dietary Patterns and Kidney Function Parameters in Adults with Metabolic Syndrome: A Cross-Sectional Study

Nutrients ◽  
2020 ◽  
Vol 13 (1) ◽  
pp. 40
Author(s):  
Ahmad Syauqy ◽  
Chien-Yeh Hsu ◽  
Hsiu-An Lee ◽  
Hsiao-Hsien Rau ◽  
Jane C.-J. Chao
Keyword(s):  
Metabolic Syndrome ◽  
Uric Acid ◽  
Kidney Function ◽  
Dietary Patterns ◽  
Dietary Pattern ◽  
Principal Component ◽  
Cross Sectional Study ◽  
Processed Food ◽  
Sectional Study ◽  
Cross Sectional

This study explored the association between dietary patterns and kidney function parameters in adults with metabolic syndrome in Taiwan. This cross-sectional study was undertaken in 56,476 adults from the health screening centers in Taiwan from 2001 to 2010. Dietary intake and dietary patterns were assessed using a food frequency questionnaire and principal component analysis, respectively. Blood urea nitrogen (BUN), creatinine, estimated glomerular filtration rate (eGFR), and uric acid were measured as clinical parameters of kidney function. Multivariate linear regression was conducted to explore the relationship between dietary patterns and kidney function parameters. After adjusting for confounders, the highest tertiles of the processed food–sweets dietary pattern and the meat–seafood–eggs dietary pattern were associated with increased BUN, creatinine, and uric acid but decreased eGFR (all adjusted p < 0.05). Meanwhile, the highest tertiles of the veggie–fruit–grains dietary pattern and the milk–dairy dietary pattern were associated with decreased BUN, creatinine, and uric acid but increased eGFR (all adjusted p < 0.05). A processed food–sweets dietary pattern or a meat–seafood–eggs dietary pattern is associated with worse kidney function parameters in adults with metabolic syndrome. In contrast, a veggie–fruit–grains dietary pattern or a milk–dairy dietary pattern is associated with better kidney function parameters.

scholarly journals Association between serum uric acid and metabolic syndrome: a cross-sectional study in Bangladeshi adults

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Nurshad Ali ◽  
Rakib Miah ◽  
Mahmudul Hasan ◽  
Zitu Barman ◽  
Ananya Dutta Mou ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Nutritional Profile and Serum Uric Acid are Associated with Metabolic Syndrome in Community-dwelling Older Adults: A Cross-sectional Study

2021 ◽  
Vol 3 (1) ◽  
pp. 4-11
Author(s):  
Ivna Vidal Freire ◽  
Denise Pereira dos Santos ◽  
Ícaro JS Ribeiro ◽  
Caroline Silva dos Santos ◽  
Raildo da Silva Coqueiro ◽  
...  
Keyword(s):  
Older Adults ◽  
Metabolic Syndrome ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Cross Sectional Study ◽  
Community Dwelling ◽  
Sectional Study ◽  
Cross Sectional ◽  
Nutritional Profile ◽  
Community Dwelling Older Adults

Association between metabolic syndrome and thyroid stimulating hormone - A cross sectional study

2019 ◽  
Vol 9 (2) ◽  
pp. 87-90
Author(s):  
Karanam Madhuri ◽  
◽  
Rishi Kumar Venkatachalam ◽  
A Nasreen Begum ◽  
Shamsheer Khan P ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Cross Sectional Study ◽  
Thyroid Stimulating Hormone ◽  
Sectional Study ◽  
Cross Sectional ◽  
Stimulating Hormone
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