A study on the clinical profile and risk factors of ischemic heart disease in women

2021 ◽  
Vol 19 (3) ◽  
pp. 130-132
Author(s):  
Sarath Kumar Reddy B ◽  

Background: Ischemic heart disease (IHD) is one of the principle causes of morbidity and of mortality in women1. Ischemic heart disease may manifest clinically as either chronic stable angina or acute coronary syndrome2 (ACS). Traditional risk factors (hypertension, diabetes, etc.) contribute to the development of IHD in both women and men. Some risk factors are unique to women (e.g., pregnancy-related complications, menopause), which cause increased mortality in women Aim: To study the risk factors and clinical profile of ischemic heart disease in women. Materials And Methods: Hospital-based prospective, cross-sectional study done in 50 patients with ischemic heart disease. Patients with a history of Chest pain suggestive of ischemic heart diseases and Electrocardiogram and cardiac biomarkers suggestive of ischemic heart disease were included in the study. Results: Maximum incidence of ischemic heart diseases is seen in the 6th decade. Mean age is 58.92 + 2.8years. 64%of the patients presented with chest pain, and 36% patients presented without any chest pain. After chest pain, the most common symptom was palpitations, seen in 56% patients, followed by sweating (44%). 30% presented to the medical facility within 3hours. 88% were diagnosed with acute coronary syndrome, and 12% were diagnosed with chronic stable angina. Women specific risk factors include the pregnancy-related complications seen in 10% patients, menopause attained in 86% patients, PCOS seen in 08% patients, use of oral contraceptive pills noticed in 08% patients, Other risk factors identified were hypothyroidism in 16% patients, connective tissue disorders like rheumatoid arthritis seen in 12% of the patients. Conclusion: Awareness regarding atypical symptoms as well as other symptoms of IHD should be created among women to avoid delayed complications. Simple lifestyle modifications like physical activity, diet modifications, etc., will reduce the number of women at risk for IHD.

2018 ◽  
Vol 3 (Issue 1) ◽  
pp. 16
Author(s):  
Leilim Actaiyeva ◽  
Kuat Abzaliyev ◽  
Simbat Abzaliyeva ◽  
Gulum Aldangarova

We present review of current evidence on ischemic heart disease in women. The risk factors, clinical manifestations, diagnosis and treatment  and prevention of ischemic heart diseases in women are discussed.


2018 ◽  
Vol 4 (6) ◽  
pp. 846-851
Author(s):  
Ashish Akshay Bedi ◽  
Ankit Gaur ◽  
Sourabh Kosey ◽  
Deepanshu Kumar Chitra ◽  
Kuldeep Singh ◽  
...  

Author(s):  
Priyanka S. Gandhi ◽  
Bhavna N. Gamit

Background: In developing countries, Ischemic heart diseases (IHD) is one of the leading causes of morbidity and mortality. The underlying pathology of CAD is atherosclerosis. When this atherosclerotic plaque ruptures, platelets play a crucial role in the prothrombotic events and forms a thrombus on this plaque and as a result coronary artery gets occluded causing ischemia and infarction. Platelet contains many chemokines, cytokines and growth factors. Release of these factors along with interaction with endothelial cells and leukocytes promotes inflammation and progression of atherosclerosis. We aimed to investigate the association between platelet volume indices in patients with diagnosis of Ischemic heart disease in comparison with control group.Methods: By using automated cell counter platelet count and platelet volume indices - were compared with Normal healthy or non-cardiac chest pain patients with the use of unpaired t test.Results: In the present study, we demonstrated that platelet count is significantly low and MPV and PDW are significantly high in Ischemic heart disease as compared to patients with noncardiac chest pain or healthy subjects. The correlation of MPV with PC revealed an inverse correlation between the patients of IHD and healthy or non-cardiac chest pain patients which is statistically significant.Conclusions: The platelet volume indices are an important, simple, effortless and a cost-effective tool useful in predicting the development of an acute coronary event sometimes in the near future and therapeutic modification for improved patient’s cardiovascular care.


Author(s):  
Hsin-I Shih ◽  
Tzu-Yuan Chao ◽  
Yi-Ting Huang ◽  
Yi-Fang Tu ◽  
Tzu-Ching Sung ◽  
...  

Natural disasters have negative health impacts on chronic diseases in affected populations. Severely affected areas are usually rural areas with limited basic infrastructure and a population have that has limited access to optimal healthcare after a disaster. Patients with cardiovascular diseases are required to maintain quality care, especially after disasters. A population-based case-control study enrolled adults from the National Health Insurance Registry who had ischemic heart disease and cerebrovascular disease histories and lived in the area affected by Typhoon Morakot in 2009. Monthly medical visits for acute cerebrovascular and ischemic heart diseases markedly increased at approximately 1–2 months after the typhoon. Survival analysis during the two years following the typhoon indicated a significant increase in mortality in adults with an acute ischemic heart disease history who lived in the severely affected area. Mortality hazard analysis showed that among affected adults with previous cerebrovascular diseases and acute ischemic heart diseases, patients with diabetes (adjusted hazard ratio [HR]: 1.3–1.7), Chronic Kidney Disease (CKD) (adjusted HR: 2.0–2.7), chronic obstructive pulmonary diseases (COPD) and asthma (adjusted HR: 1.7–2.1), liver cirrhosis (adjusted HR: 2.3–3.3) and neoplasms (adjusted HR: 1.1–2.1) had significantly increased mortality rates. Consequently, high-quality and accessible primary healthcare plans should be made available to maintain and support affected populations after disasters.


2018 ◽  
Vol 15 (2) ◽  
pp. 25-32
Author(s):  
Sangita Shrestha ◽  
Shova Laxmi Bajracharya

Background and Aims: Ischemic Heart Disease (IHD) is the number one cause of morbidity and mortality among the in-patient of different cardiac hospital of developing countries like Nepal. The prevalence of IHD is high with significant associated risk factors that include tobacco use, history of hypertension, family history and age. Though IHD can cause life-threatening conditions like myocardial infarction, yet it is preventable disease. The objective of the study was to study the risk factors associated with ischemic heart diseases among population attending selected cardiac hospitals of Kathmandu.Methods: Hospital- based pair matched case-control was conducted among the patients with IHD at Manmohan Cardiothoracic Vascular and Transplant Centre (MCTVC) and Shahid Gangalal National Heart Center (SGNHC). Non- random purposive sampling technique was applied and sample size was calculated as 105 (35 cases and 70 controls). Case and control were matched with age (Å} 2 years) and sex from the same hospitals. Ethical approval was taken from Institutional review board, Institute of medicine. Informed consent was obtained prior to information collection, after explaining about the purpose of the study to the entire participants. Only interested participants were included in the study. Confidentiality of the subject was ensured by collecting data in separate private room. Univariate associations between the risk factors and IHD under study was assessed by applying Chi-Square test and Fisher’s exact test and expressed as odds ratios with 95% confidence intervals. To assess the strength of association, the odds ratio was calculated.Results: 88.6% cases and 90% controls participants were of age 41 years and above and IHD was more common in male (60%) than female (40%). The participants who were not doing work-related moderate-intense activity are twice more likely to have IHD compared to controls (OR=2.276, p=0.049), similarly, hypertensive are two times (OR=2.276, p=0.049), obese are more than two times (OR=2.44, p=0.045), and participants with high waist to hip ratio are almost three times more likely to suffer from IHD (OR=2.88, p=0.013).Conclusions: The current smoking, physical inactivity, hypertension and waist to hip ratio tend to be the significant risk factors of IHD. Minimizing exposure to the identified risk factors can prevent burden of complex and expensive IHD treatment.


2020 ◽  
Vol 6 (4) ◽  
pp. 138-144
Author(s):  
Tati Suryati ◽  
Suyitno Suyitno

Background: The Cardiovascular disease (CVDs) is leading in the world as a number one cause of death.  Ischemic Heart Disease (IHD) part of CVDs which is often also called coronary artery disease.Objective: The purpose this study is to know the risk factors for ischemic heart disease in Indonesia, 2013.Methods: The risk assessment analyzes was used to exam the risk factor IHD around 721,427 people from data of Basic Health Research (RISKESDAS) 2013 in Indonesia.Results: The finding of this study was former smoker (Adj. OR= 4.09, 95% C.I=3.78-4.43), hypertension (Adj. OR= 3.80, 95% C.I=3.60-4.10), obesity (Adj. OR= 1.96, 95% C.I=1.84-2.08), low consumption of fruits and vegetables (Adj. OR= 0.70, 95% C.I=0.57-0.87), and low physical activity (Adj. OR= 1.14, 95% C.I=1.06-1.23) are risk factor of IHD in Indonesia, 2013.Conclusion: The central, regional, and even village level special attention have a need for reducing IHD. Cross-program and sector collaboration are also needed collaboration with NGOs and the private sector to control risk factors outside the health sector and improve the environment.


World Science ◽  
2019 ◽  
Vol 2 (11(51)) ◽  
pp. 4-11
Author(s):  
Mostovyi S. ◽  
Dynnyk O. ◽  
Marunchyn N.

Introduction. It is known that patients with ischemic heart diseases have endothelial dysfunction, but there is lack of research about microcirculation in these patients with diffuse liver diseases, especially diagnosed with digital capillaroscopy. Aim. To investigate hemodynamic disorders and microcirculation in patients with chronic ischemic heart disease depending on the presence of diffuse liver diseases and its severity with the digital capillaroscopy. Materials and methods. Our prospective study included 187 patients according to the criteria of inclusion. The data of echocardiography and digital capillaroscopy were analysed. Results. In our research in patients with ejection fraction less than 40% there was revealed thickening of the wall of the left ventricle, low blood supply in arterial and venous parts of capillaries. Patients with ejection fraction less than 40% and progressive diffuse liver diseases had advanced thickening of the wall of the left ventricle. Patients with liver cirrhosis had more adverse changes in hemodynamics. Patients with ischemic heart disease and diffuse liver disease had the worst capillary blood supply. Patients with ejection fraction less than 40% and diffuse liver diseases had structural changes of capillaries such as bi-, trifurcation and bushy forms. Conclusions. So, diffuse liver diseases, especially severe, cause endothelial dysfunction in patients with ischemic heart diseases. Digital capillaroscopy is a noninvasive method for microcirculation diagnosis and patients’ monitoring.


2000 ◽  
Vol 39 (03) ◽  
pp. 223-228 ◽  
Author(s):  
H. Ohno ◽  
M. Tamura ◽  
K. Kawakubo ◽  
A. Gunji ◽  
H. Kashihara

AbstractObjectives: In Japan controversy exists as to whether or not the risk factors for ischemic heart disease (IHD) are the same as in western countries. We conducted a case-control study on IHD to clarify the risk factors in males in an urban area of Japan using our automated multiphasic health testing and services (AMHTS) system. Method: Cases were the clients who took the health check-up between January 1987 and July 1994 and had onset of IHD after the check-up. For each case five clients were selected as controls by conditional matching. The check-up data were compared between cases and controls 11 years, 6 years and just before the onset of the heart diseases. Results: The statistically significant items were as follows: (1) Eleven years before the onset: Total cholesterol (T-Chol) for myocardial infarction (MI), and fasting blood sugar (FBS) for angina pectoris (AP). (2) Six years before the onset: T-Chol, electrocardiographic (ECG) findings and the complaint of palpitation or breathlessness for MI, and FBS and palpitation or breathlessness for AP. (3) Just before the onset: T-Chol, the complaint of chest pain, FBS, smoking index and hypertensive status for MI and palpitation or breathlessness, ECG findings, chest pain, systolic blood pressure and erythrocyte sedimentation rate at 60 minutes for AP. In conclusion, the risk factors for MI in males in an urban area of Japan are the same as in western countries. The most significant risk factor for AP in males in an urban area of Japan is fasting blood sugar.


2019 ◽  
Vol 34 (2) ◽  
pp. 122-126 ◽  
Author(s):  
Anisur Rahman Khan ◽  
AKM Azad Hossain ◽  
Md Akteruzzaman ◽  
Sabina Jesmin ◽  
Md Salahuddin Ulubbi ◽  
...  

Background: Ischemic Heart Disease (IHD) is preventable and reversible if early screening and elimination of the risk factors like life style modification and dietary intervention can be done. Exercise Tolerant Test (ETT) has become an important diagnostic tool to evaluate patient with suspected or known case of ischemic heart disease. Objective: To determine the frequency of IHD among subjects who presented with chest pain and to identify the common indications for ETT. Methodology: It was a cross-sectional study; the data was collected from ETT Unit of Mugda Medical College Hospital, Dhaka, Bangladesh using standard Bruce protocol. Result: Out of 200 patients, there were 124(61%) male and 78(39%) female who presented in the cardiology department for ETT. Common indications for ETT were evaluation of chest pain 180(90%), followed by general check-up 14(7%), post-PCI evaluations 4(2%) and post- CABG evaluation 2(1%).Presenting complaints were typical angina 12(6%), shortness of breath 56(28%), nonspecific chest pain 82(41%), chest compression 46(23%) and others 4(2%). Exercise ECG showed no ST changes in 138(69%) patients. The most common risk factors were hypertension, diabetes, smoking and obesity. Majority of the subjects 136(68%) were test negative whereas 42 (21%) were test positive and 22(11%) were test equivocal. Conclusions: It is concluded that most of the subjects presenting with the suspected symptoms of myocardial ischemia were negative for IHD, and so why we advocate the use of ETT as a screening tool in patients who presents with features simulating angina. This will prevent unnecessary hospital admission. Bangladesh Heart Journal 2019; 34(2) : 122-126


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