scholarly journals A prospective study of clinical profile of patients with acute kidney injury following acute gastroenteritis

2020 ◽  
Vol 16 (1) ◽  
pp. 53-56
Author(s):  
Dnyaneshwar Malharrao Ghuge ◽  
Keyword(s):  
Acute Kidney Injury ◽  
Acute Gastroenteritis ◽  
Early Recognition ◽  
Kidney Injury ◽  
Clinical Profile ◽  
Common Symptom ◽  
Age Group ◽  
Female Ratio ◽  
Number Of Patients ◽  
Co Morbidity

Background: Increasing number of patients of AGE are now diagnosed with AKI.. Over the recent years there has been increasing recognition that relatively small rises in serum creatinine in a variety of clinical settings are associated with worse outcomes. In present study, we aimed to study clinical profile of patients with acute kidney injury following acute gastroenteritis at our tertiary hospital. Material and Methods: Present study was conducted in patients who were diagnosed to have AKI following acute gastroenteritis. Statistical analysis was done using descriptive statistics. Results were expressed as mean and standard deviation for continuous data and frequency as number and percentage. Results: After applying inclusion and exclusion criteria, total 72 patients of AGE with AKI were considered for this study. Most common age group in this study was age group of 61–70 years (28%), followed by age group of 51–60 years (25%). Mean age of study patients was 53.8 ± 11.7 years. Male patients (64%) were more than female patients (36%). Male to female ratio was 1.8:1. According to clinical presentation most common symptom was loose stools (100 %), followed by fever (76 %) and vomiting (68 %). Other complaints were shortness of breath (18 %) and altered sensorium (8 %). Diabetes was the most common co-morbidity noted (39 %) followed by hypertension (34%). AKI was staged for severity according to the KDIGO criteria. At the time of diagnosis most patients were in stage 1 (57%), while 32% and 11% were in stage 2 and 3 respectively.In this study hypotension, hyperkalemia were common complications of Acute Kidney Injury. Other complications were metabolic acidosis, encephalopathy, pulmonary edema, anemia, multi organ dysfunction syndrome (MODS), hypokalemia and hyponatremia. In present study, 11% patients underwent hemodialysis and 3 % mortality was noted. Conclusion: Acute kidney injury in patients with acute gastroenteritis had good prognosis if detected earlier. Early recognition of AKI is essential to ensure prompt and appropriate management, and to avoid progression to deadlier stages of the disease.

scholarly journals Hymenoptera stings: a study of clinical profile, complication and outcome from a teaching hospital of central Nepal

2014 ◽  
Vol 9 (3) ◽  
pp. 17-24 ◽  
Author(s):  
M Ghimire ◽  
B Pahari ◽  
N Paudel ◽  
G Das ◽  
SK Sharma ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Serum Albumin ◽  
Teaching Hospital ◽  
Kidney Injury ◽  
Clinical Profile ◽  
Common Complication ◽  
Medical Sciences ◽  
Female Ratio ◽  
Hymenoptera Sting ◽  
The Mean

Background Hymenoptera sting is a common health hazard in the tropics. Wasp and Bee stings can produce symptoms ranging from local allergic reactions to serious complications including anaphylaxis and multiple organ dysfunction syndromes.Objective To evaluate the clinical profile, management and early outcome of patients with gallbladder cancer.Methods We prospectively analyzed all the consecutive patients with Hymenopterid sting (Wasp and Bee stings), who were admitted in Nephrology Unit in college of Medical Sciences Teaching hospital over a period of two year; from June 2010 to May 2012. Data including demographic profile, clinical profile, complications and outcomes associated with the Hymenopterid stings were entered in a designated profroma and were analyzed.Results A total of 15 cases with Hymenopterid stings (Wasp and Bee stings) were analyzed. Majority of the cases were females (n=8). The male to female ratio was 0.88. The mean age of the case was 37.1± 17.38years. Most of the cases (n=11) were younger subjects d"45 years and majority of them felt in the age group of 21-30 years; (n=4). Mean number of stings (Wasp or Bee stings), were 46 ± 18.4 (12-74) and the mean time to reach the hospital from the bite time was 78.23±82.24 hours (30 minutes-13 days). Black Wasps were the commonest species to inflict the stings in (n=10) cases and Bees in (n=5) cases. The Hymenoptera stings were observed more frequently in the month of July to September in (n=8). The commonest site of bite was head and face seen in (n=11) cases. Among the clinical presentations the commonest clinical presentation was local burning pain and pruritus which was present in all the cases (n=15) followed by nausea (n=10). The commonest clinical sign was bipedal edema which was seen in (n=7) cases. Low Hb (defined as Hb <10gm/dl) was seen in (n=5) cases of Hymenopterid stings. Low platelet (defined as Platelet < 100X109/L) was documented in (n=10) cases. Serum creatinine >1.5mg /dl was seen in (n=7) cases. Low serum albumin (defined as Serum Albumin (<3.5gm/dl) was seen in (n=6) cases. Among the complications, the most common complication was Hepatitis which was seen in (n=9) cases, followed by Acute Kidney Injury. There was no mortality associated with Hymenopterid stings in our study. However 1 patient left against medical advice.Conclusion Black Wasps were the commonest species to inflict the stings in (n=10) cases. The most common complication of Hymenoptera sting was Hepatitis, which was seen in (n=9) of cases, followed by Acute Kidney Injury. Majority of complications were seen in Wasp stings which caused significant morbidity. No mortality was observed in our study except one case; that left hospital against medical advice. Journal of College of Medical Sciences-Nepal, 2013, Vol-9, No-3, 17-24   

scholarly journals A study on outcome of malaria and acute gastroenteritis induced acute kidney injury requiring hemodialysis

2018 ◽  
Vol 5 (3) ◽  
pp. 681
Author(s):  
Swarna Gupta ◽  
Punit Gupta ◽  
Vishal Jain
Keyword(s):  
Acute Kidney Injury ◽  
Peritoneal Dialysis ◽  
Kidney Function ◽  
Acute Gastroenteritis ◽  
Univariate Analysis ◽  
Disease Onset ◽  
Kidney Injury ◽  
Co2 Removal ◽  
Waste Products ◽  
Number Of Patients

Background: Acute kidney injury previously known as acute renal failure, is characterized by the sudden impairment of kidney function resulting in the retention of nitrogenous and other waste products normally cleared by the kidneys.   Acute Kidney Injury is usually manifested as multiorgan failure syndrome and extracorporeal support may also target fluid overload and heart failure, extracorporeal CO2 removal for combined kidney and lung support, albumin dialysis for liver support. Haemodialysis is more effective than peritoneal dialysis for management of Acute Kidney injury as Peritoneal dialysis is associated with clearance limitation and difficulties with fluid removal and is thus rarely used in adults in developed countries.Methods: The study was conducted in the Department of Medicine, Pt. J.N.M. Medical College and Dr. B.R.A.M. Hospital, Raipur (CG), India, from 2010 to 2012. All patients of both the sexes who were diagnosed as a case of Acute Kidney Injury due to Acute Gastroenteritis and Malaria and who were advised for Hemodialysis were included in the study. In our study, 32 patients of Acute Kidney Injury were included. The criteria used for AKI in the study was RIFLE criteria. Hemodialysis was done in all the cases. Quantitative variables are reported as means±SD and qualitative variables as percentage. Factor(s) determining outcome of AKI were tested by univariate analysis using “fisher’s exact test”. All variables with a P value <0.05 in the univariate analysis were defined statistically significant.Results: Out of 32 patients of Acute Kidney Injury in our study, 50% (n=16) were of Malaria associated AKI cases and other 50% (n=16) patients were of Acute Gastroenteritis associated AKI in which 87.5% males,12.5% Females were of Malaria and 75% male,25% Female were in AGE associated AKI. Maximum number of patients presented with features of AKI within first 3days of disease onset i.e. 56.25% (n=9) of malaria patients and 68.75% (n=11) of AGE patients. Mortality due to MOD was more common in Malaria patients as compared to AGE patients. AGE associated AKI patients had different level of deranged SOFA score.Conclusions: Acute kidney injury due to acute gastroenteritis differs from other causes of AKI by frequent occurrence of hypokalemia. Early diagnosis and prompt management can restore the kidney function.

scholarly journals Clinical profile and outcome of organ dysfunction in sepsis

2018 ◽  
Vol 6 (6) ◽  
pp. 1927
Author(s):  
Laxmikanta Dash ◽  
Lagendra Kumar Singh ◽  
Malati Murmu ◽  
Susruth Krishnadas P. ◽  
Amita Kerketta ◽  
...  
Keyword(s):  
Organ Dysfunction ◽  
Clinical Profile ◽  
Apache Ii Score ◽  
Common Symptom ◽  
Age Group ◽  
Elderly Age ◽  
Female Ratio ◽  
Common System ◽  
Source Of Infection ◽  
Life Threatening

Background: Sepsis is defined as life threatening organ dysfunction due to a dysregulated host response to infection. It is the tenth leading cause of death among older adults in United States. Mortality rate of the sepsis ranges from 30-40%. In severe cases sepsis can drastically reduce blood flow to the major organs, leading eventually to septic shock, widespread organ failure and death. So, the present study was done to evaluate the clinical profile, symptoms, source of infection, co-morbid conditions and outcome with respect to the organ dysfunction in sepsis cases.Methods: This prospective observational study was undertaken among 100 cases of sepsis diagnosed by the “International Sepsis Definitions Conference” criteria admitted during October 2015 to September 2017. All patients were evaluated clinically and subjected for laboratory investigations.Results: In present study, a total of 100 cases were enrolled. Mean age of cases were 38.15 years. Male and female ratio was 1.63:1. Most common symptom was fever (100%). Pneumonia was the most common (36%) source of infection. Mortality was highest in pneumonia (55.55%). 77 % of cases had organ dysfunction. Cardiovascular system was the most common system involved. Maximum mortality was within the age group of 56-65 years. Diabetes was the most common co-morbid condition. Mean APACHE II score was high among the death cases.Conclusions: Sepsis was more common in younger group of patients but mortality was more in elderly age group. Overall mortality was 38%. 

scholarly journals A study of clinical profile of patients with chronic pulmonary obstructive disease at a tertiary care centre in North Karnataka, India

2019 ◽  
Vol 6 (2) ◽  
pp. 455
Author(s):  
Ashok Kumar Gudagunti ◽  
Ishwar Hasabi ◽  
Arathy S.
Keyword(s):  
Tertiary Care ◽  
Cross Sectional Study ◽  
Clinical Profile ◽  
Common Symptom ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Female Ratio ◽  
Chronic Pulmonary Obstructive Disease ◽  
Obstructive Disease ◽  
Co Morbidity

Background: Chronic pulmonary obstructive disease (COPD) has been responsible for the decreased quality of life as well as increased morbidity and mortality. Globally it has been estimated that nearly three million die yearly due to COPD and more likely to occupy the third place of mortality by 2030. The objective of the present endeavour was to study clinical profile of patients with chronic pulmonary obstructive disease at a tertiary care centre.Methods: A hospital based cross sectional study was carried out among 200 cases of COPD. Their detailed history, thorough clinical examination and parameters like hemoglobin, serum creatinine, protein etc were investigated. The presence of co-morbidities was noted.Results: As the age increased the prevalence of the COPD increased and highest was found out to be in the age group of above 60 years of age. Males were more affected with COPD as compared with females. The male to female ratio was found out to be 2.4:1. The smokers were more compared to the non smokers. The prevalence of smoking among COPD was noted to be 66% compared to 34% as non smokers. Least proportion of patients of the COPD had fever i.e. in 22% of the cases. Cough was found in 83% of the cases. Breathlessness was found out to be in 98% of the cases. 15% of the cases of the COPD had diabetes only as the co-morbidity along with COPD and no other co-morbidity.Conclusions: Breathlessness was the most common symptom at presentation and diabetes and hypertension were the most common co-morbidities found.

Clinical profile of acute kidney injury in a tertiary hospital

2019 ◽  
Vol 10 (2) ◽  
pp. 59-61
Author(s):  
M Rama Subba Reddy ◽  
◽  
S Senthil Kumar ◽  
A Nasreen Begum ◽  
A Shanmuga Priya ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Tertiary Hospital ◽  
Clinical Profile

Study of clinical profile of patients with acute kidney injury

2019 ◽  
Vol 12 (1) ◽  
pp. 06-09
Author(s):  
Anil Rathi ◽  
◽  
Gajanan Gondhali ◽  
Sushil Bhattad ◽  
◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Clinical Profile
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