Study of clinico-etiological profile of neonatal seizures in term neonates at a tertiary care hospital

2021 ◽  
Vol 19 (2) ◽  
pp. 38-41
Author(s):  
Santosh K Kulkarni ◽  
2020 ◽  
Vol 8 (9) ◽  
pp. 2194-2197
Author(s):  
Mohammad Moniruzzaman Bhuiyan ◽  
Nadira Dilruba Hoque ◽  
Mahfuza Nasrin ◽  
Ibrahim Khalil ◽  
Nasrin Akhter

2017 ◽  
Vol 4 (6) ◽  
pp. 2165
Author(s):  
Abdul Naseer Abdul Bari ◽  
Habib G. Pathan ◽  
Prashant R. Kokiwar

Background: Seizures are associated with poor neuro developmental outcome if not diagnosed early and treated properly. During newborn period, seizures indicate underlying neurological disease. Neonatal seizures lead to increased morbidity and mortality usually found in neonatal intensive care unit. The objective of this study was to evaluate incidence and outcome of neonatal seizures.Methods: Present study was hospital based prospective study conducted among 117 neonates of 0-28 days of age at a tertiary care hospital for a period of one year. The data like history, clinical examination and investigation findings was recorded in the pre-designed, pre-tested, semi structured questionnaire.Results: The incidence of neonatal seizures was higher in male neonates. Subtle types of seizures were the commonest type of seizures. In term neonates, the birth asphyxia was the most common cause of neonatal seizures. The incidence of intra-ventricular hemorrhage (IVH) was significantly higher in preterm than term neonates. Out of biochemical abnormalities, the hypocalcemia was the most common cause of the neonatal seizures. Common causes of neonatal deaths in our center were severe birth asphyxia, intra-ventricular hemorrhage (IVH), septicemia and meningitis. Conclusions: Most of the causes of neonatal seizures are preventable by good perinatal care and early interventions while metabolic seizures need a sharp vigilance and early suspicion. 


Author(s):  
E. S. Sushmitha ◽  
D. Manoj ◽  
K. Ravindra ◽  
G. Guruprasad

<p class="abstract"><strong>Background:</strong> Neonatal dermatology, by definition, encompasses the spectrum of cutaneous disorders that arise during the first four weeks of life ranging from from physiological and transient to grossly pathological lesions in the skin of a neonate. The aim and objectives of the study were to determine the quantum of iatrogenic problems which can be minimized and prevented.</p><p class="abstract"><strong>Methods:</strong> A total of 1000 neonates admitted in the tertiary care NICU of JJM Medical College were examined and spectrums of pathological cutaneous lesions noted.<strong></strong></p><p class="abstract"><strong>Results:</strong> Among 1000 neonates examined, 101 had iatrogenic cutaneous conditions which were commonly seen in day one of life in 48 neonates and least in newborns between 15-21 days. Skin lesions were commonly seen in full term neonates (59), followed by preterm (39) and post term (3) neonates.Among the iatrogenic injuries needle prick injury (83), thermal burns (12) and bronze baby syndrome (11) were most commonly were noted in LBW and the normal for weight neonates. A variety of other conditions which could not be categorized into any of the above categories accounted for 5 cases. These included albinism, Waardenburg syndrome, TORCH complex and Down’s syndrome and Goltz syndrome.</p><p class="abstract"><strong>Conclusions:</strong> Iatrogenic cutaneous abnormalities among neonates are under reported, with no detailed studies on these variants. Genetic, neonatal, maternal, social and geographic factors seen to influence the patterns of neonatal dermatoses. Hence, it is important for a dermatologist and paediatrician to have a thorough knowledge and to distinguish various iatrogenic manifestations and to minimize the outcomes during their stay in NICU.</p>


Author(s):  
Iqbal Mushtaq ◽  
Haamid Ismail ◽  
Zul Eidain Hassan ◽  
Fozia Hussain Shah ◽  
Kaiser Ahmad ◽  
...  

Author(s):  
Mohanram V. ◽  
Arulraj Russelian ◽  
Palpandi V.

Background: Several factors contribute to seizures among neonates. To avoid complications from under recognition of clinical seizures and the adverse effects of medications administered, the diagnosis and management of neonatal seizures necessitate an interprofessional approach. Present study was done to study the clinical and biochemical profile of neonates with seizures admitted to a tertiary care hospital, Chennai.Methods: A cross sectional study was conducted where all the neonates from birth to 28 days of life who got admitted in the neonatal intensive care unit (NICU) of a tertiary care hospital-Shri Sathya Sai medical college and research institute were included in the study. Baseline characteristics of all the babies were noted on the prescribed proforma. Thorough physical examination was done and seizures were diagnosed by clinical observation. Clinical details of each seizure episode were recorded like age at onset of seizures, duration of seizure, number and type of seizure.Results: In the present study, 50 neonates satisfying the inclusion and exclusion criteria were included in the study. The main mode of delivery was normal vaginal delivery (50%) followed by LSCS (40%) and assisted delivery (10%). 54% were male and 46% were female and majority of babies were delivered at term i.e., 72% and 28% were pre term babies. The mean day of onset of seizures in the present study was 3.18±2.09. Based on day of onset of seizures, with in 24 hrs (28%), 24 hrs to 72 hrs (46%), 4th day to 1 week (22%), more than 1 week (4%). Based on type of seizure 64% had subtle type, 26% had tonic type and 10% had clonic type of seizures. In this study, 24% had hypoglycemia, and 10 (20%) had hypocalcemia, 14% in the present study had hyponatremia, and 2 (4%) had hypomagnesemia, 2 (4%) had hypernatremia, 6% had combination of hypocalcemia and hypoglycemia.Conclusions: Hypocalcemia, hypoglycemia, hyponatremia were the common biochemical abnormalities observed in our study. Subtle seizures were the common type of seizures observed among both pre term and term infants.


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