Study of role of iron deficiency anaemia in childhood febrile seizures in a tertiary care centre

2019 ◽  
Vol 12 (3) ◽  
pp. 75-78
Author(s):  
Sunil Kumar ◽  
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anaemia ◽  
Tertiary Care ◽  
Febrile Seizures ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Deficiency Anaemia

scholarly journals Study of Role of Iron Deficiency Anaemia in Febrile Seizures in Children in a Tertiary Care Centre

2016 ◽  
Vol 35 (2) ◽  
pp. 148-151
Author(s):  
Bheema Naik Sreenivasa ◽  
Gowripura Visweswaraiah Kumar ◽  
Bheema Naik Manjunatha
Keyword(s):  
Risk Factor ◽  
Iron Deficiency ◽  
Iron Deficiency Anaemia ◽  
Febrile Seizures ◽  
Deficiency Anemia ◽  
Age Group ◽  
Febrile Convulsions ◽  
Deficiency Anaemia ◽  
The Mean

Introduction: The world health organization estimates that anaemia largely caused by iron deficiency, affecting between 500 million and two billion people worldwide. Considering the age prevalence of iron deficiency anaemia and febrile convulsion which are the same, the role of iron in the metabolism of neurotransmitter and some enzymes, the function of hemoglobin in conveying oxygen to the brain and since fever can exacerbate symptoms that result from anaemia, a relationship between iron deficiency anaemia and febrile convulsions is probable. Some studies have suggested iron deficiency as a predisposing factor for febrile seizures. We designed this case control study to evaluate the relationship between iron deficiency anaemia and febrile convulsions. The objective of this study was to study the role of iron deficiency as a risk factor for febrile seizures.Materials and Methods: Hundred cases and 100 controls were included in the study. Cases were children of age group six months to six years presenting with febrile seizures. Controls were children of same age group presenting with febrile illness but without any seizures. After informed consent, detailed history was taken and clinical examination done in both cases and controls and blood investigations were done to diagnose iron deficiency anemia. Two groups were matched for age and sex. In all children hemoglobin (Hb) level, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), red cell distribution width (RDW) and plasma ferritin (PF) were determined and the data collected were analyzed statistically.Results: The mean PF was significantly lower in cases compared to controls (p=0.000) and RDW was significantly higher in cases compared to controls (p=0.00). The mean Hb%, MCV, MCH are lower in cases compared to controls but it was statistically not significant.Concluson: Iron deficiency is a significant risk factor for febrile seizures in children of age group six months to six years. Early detection and timely correction of iron deficiency may be helpful for prevention of febrile seizures in children.J Nepal Paediatr Soc 2015;35(2):148-151

scholarly journals Safety and Efficacy of Intravenous Ferric Carboxymaltose for Treatment of Iron Deficiency Anaemia in Pregnancy - An Intervention Study Done in a Tertiary Care Hospital of Pune

2021 ◽  
Vol 8 (22) ◽  
pp. 1803-1807
Author(s):  
Anish Kumar Vishal ◽  
Dinesh Bhasin ◽  
Vidhu Dhar Dangwal ◽  
Anurakshat Bhasin
Keyword(s):  
Iron Deficiency ◽  
Blood Transfusion ◽  
Serum Ferritin ◽  
Iron Deficiency Anaemia ◽  
Tertiary Care ◽  
Ferric Carboxymaltose ◽  
Third Trimester ◽  
Deficiency Anaemia ◽  
Anaemia In Pregnancy ◽  
In Pregnancy

BACKGROUND Anaemia is one of the major public health problems in developing nations. Iron deficiency anaemia (IDA) is the commonest type of anaemia in pregnancy. Parenteral iron therapy is a recommended modality of treatment of IDA. Inj. Ferric Carboxymaltose (FCM) is a dextran free preparation which is safe, easy to deliver and better tolerated. A maximum of 1000 mg can be infused at a time. The present study was intended to assess the efficacy and safety of Inj. FCM in the treatment of iron deficiency anaemia in the second and third trimester. METHODS This prospective study was conducted at a tertiary care centre at Pune. Pregnant women with iron deficiency anaemia of moderate and severe grade were infused 1000 mg of Inj. FCM by longer infusion protocol. A total of 165 pregnant women were included in the study. The efficacy of Inj. FCM was monitored by the rise in the haemoglobin level at 03-, 06- and 08-weeks post infusion of FCM injection and serum Ferritin levels. The safety was assessed by analysing the adverse reactions. RESULTS No serious adverse reaction was recorded in any of the patients. The rise in haemoglobin (Hb) in second and third trimester of moderate and severe grade of anaemia was significant (P < 0.001). The target level of 10 g / dl was achieved in every patient. Only 03 patients received blood transfusion and that was for obstetric indications. No blood transfusion was because of anaemia per se. The rise in serum ferritin level was also statistically significant (P < 0.001). CONCLUSIONS Inj. FCM is an excellent modality to treat iron deficiency anaemia in pregnancy. It is safe and the rise of haemoglobin with correction of anaemia is satisfactory in a short span of time. In our country where only a handful of patients had regular antenatal check-up and non-compliancy and refractory anaemia is rampant, Inj. FCM is a big boon. KEYWORDS Iron Deficiency Anaemia, Inj. Ferric Carboxymaltose, Serum Ferritin, Blood Transfusion

scholarly journals Role of Colposcopy in Evaluation of Abnormal Cytology a Tertiary Care Centre Experience

2020 ◽  
Vol 10 (3) ◽  
pp. 130-134
Author(s):  
Sachan Rekha ◽  
Shukla Ayushi ◽  
Sachan Pushpalata ◽  
Patel ML ◽  
Shankhwar Pushpalata
Keyword(s):  
Tertiary Care ◽  
Care Centre ◽  
Abnormal Cytology ◽  
Tertiary Care Centre

scholarly journals Role of faecal occult bloods in the diagnosis of iron deficiency anaemia

2014 ◽  
Vol 5 (4) ◽  
pp. 231-236 ◽  
Author(s):  
A T M Dilshad Chowdhury ◽  
Gaius Longcroft-Wheaton ◽  
Andrew Davis ◽  
David Massey ◽  
Patrick Goggin
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anaemia ◽  
Deficiency Anaemia ◽  
Faecal Occult
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