Prospective study to assess socio demographic and clinical profile of non-compliant patients on topical anti glaucoma medications in rural hospital in southern India

2021 ◽  
Vol 19 (3) ◽  
pp. 35-37
Author(s):  
Farheen Sana shakir ◽  
Keyword(s):  
Sample Size ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Pressure Control ◽  
Clinical Profile ◽  
Open Angle ◽  
Chi Square ◽  
Continuous Care ◽  
Chi Square Test ◽  
Topical Medications

Background: Aim: To assess the socio demographic and clinical profile of non-compliant primary open angle glaucoma patients on topical antiglaucoma medications. To assess the reasons for noncompliance in these patients. Methodology: This study was an Observational study which was conducted in Ophthalmology OPD at Kodagu Institute of Medical Sciences, Madikeri, from March 2020 to June 2021. Patients selected were those on topical medications for primary open angle glaucoma of age > 18 years. 95 patients were selected and where given questionnaire. The formula used here to calculate the sample size was sample size n= Za2 p(1-p)/ e2. The prevalence of POAG is 3.51 %(1 Hence n=83. We have included 95 patients in our study. The statistical analysis was done using percentage, frequency and Chi square test. Approval from the ethical committee of the institution was taken before starting the study. Informed consent of the patient was taken. Patients were given the questionnaire and were asked to answer. The questionnaire included- mentioning the details of the antiglaucoma drug being used, duration of usage,missing of doses, reasons for missing the dosage etc was provided to the patients. Results: Total number of 95 patients took part in this study. Among them males and females were 45.2% and 54.7% respectively. Missing of dosage in the previous two weeks was considered as non compliant with regimen. Results showed that 28 out of 95 patients, (29.4%) were non compliant to the drug regime. Conclusion: In glaucoma patients, adherence to topical antiglaucoma medications is a major challenge As antiglaucoma therapy has to be used for lifelong and requires continuous care, awareness has to be created regarding the consequences of missing their medication and the importance of adhering to prescribed regimens. Different aspects about the cost of the medication, drug usage frequency, and side effects has to be considered and not just intraocular pressure control. Complete understanding of these factors and good counseling of the patient and their attenders can definitely improve the compliance of such patients and therefore the success of the treatment.

scholarly journals Correlation between functional staging and DDLS in primary open angle glaucoma patients in Vietnam

2021 ◽  
Vol 18 (2) ◽  
Author(s):  
Anh Van Thi Bui ◽  
Thom Thi Vu ◽  
Tung Thanh Hoang
Keyword(s):  
Visual Field ◽  
Intervention Study ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Mean Deviation ◽  
Fisher Exact Test ◽  
Open Angle ◽  
Chi Square ◽  
Exact Test ◽  
Chi Square Test

Background: Clinically, there are many systems of visual field staging parallel exist. The agreement between glaucoma function and appearance is still uncertain. This study was to compare visual field staging classifications (as function staging) with disc damage likelihood scale (DDLS as appearance staging) in primary open angle glaucoma (POAG).Methods: Cross-section study on 55 patients (90 eyes) examined and treated in Vietnam National Institute of Ophthalmology from 9/2016 – 9/2017. The MD (mean deviation), PSD (pattern standard deviation), VFI (visual field index) indexes were recorded and were used to classify glaucoma staging according to categories of eGSS (enhance glaucoma severity staging), mGSS (modified glaucoma severity staging), HPA (Hoddaps – Palmela – Adersons), AGIS (advance glaucoma intervention study) and DDLS. Using SPSS 16.0 software, statistically significance was tested with proper tests as Chi – square test, Fisher exact test, Kappa (to assess the agreement - disagreement), Spearman Rank (to assess the level of correlation).Results: Mean visual field indexes were -11.49 dB (MD), 5.85 dB (PSD), 74.2% (VFI). Compared to the DDLS, all systems had slight agreement (K < 0.2). The disagreement percentage was highest in eGSS (70%) then followed by mGSS (50%) and HPA (48.9%). In terms of definitive diagnosis, HPA and mGSS showed a substantial agreement (K > 0.6) with AGIS which is higher than that between eGSS and AGIS (retrospectively 0.773 and 0.75 vs 0.399) with p < 0.001. In terms of staging detection, the agreement between HPA &mGSS and AGIS was substantial (K > 0.6) while that between eGSS and AGIS was fair (K < 0.4).Conclusion: mGSS and HPA tend to show the stronger agreement with standard classifications than eGSS. mGSS should be used in clinical practice and research.

scholarly journals Intraocular pressure control after trabeculectomy in the patients with primary open angle glaucoma and pseudoexfoliative glaucoma followed up for 3 to 5 years

2019 ◽  
Vol 76 (8) ◽  
pp. 822-829
Author(s):  
Vesna Maric ◽  
Vujica Markovic ◽  
Marija Bozic ◽  
Ivan Marjanovic ◽  
Paraskeva Hentova-Sencanic ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Survival Curve ◽  
Pressure Control ◽  
Safe Procedure ◽  
Open Angle ◽  
Success Rates ◽  
Pseudoexfoliative Glaucoma ◽  
Significant Difference

Background/Aim. Trabeculectomy is a safe procedure which effectively reduces the intraocular pressure (IOP). IOP is the most frequent indicator of success after glaucoma surgery. The aim of this work was to evaluate the long-term pressure control in primary open-angle glaucoma (POAG) and in pseudoexfoliative glaucoma (XFG) after primary trabeculectomy without the use of mitomycin-C (MMC), 3 to 5 years after trabeculectomy. Methods. This study involved a retrospective evaluation of 332 consecutive patients (352 eyes), 174 patients (188 eyes) with POAG (mean age of 64.0 ? 8.6 years) and 158 patients (164 eyes) with XFG (mean age of 70.7 ? 8.9 years) who underwent primary trabeculectomy between January 2007 and December 2009 at the Clinic for Eye Diseases, Clinical Center of Serbia in Belgrade. A successful control of IOP was defined as achieving IOP ? 21 mmHg without medication (complete success), or with a single topical medication (qualified success). Results. According to the type of glaucoma POAG/XFG preoperative IOP was 28.4 ? 6.3/30.4 ? 8.4 mmHg, respectively (p = 0.311) and last postoperative IOP was 16.9 ? 5.2/18.7 ? 5.9 mmHg, respectively (p = 0.681). According to the Kaplan-Meier survival curve, the complete success in the group with POAG in 1, 3 and 5 years were 85%, 75% and 58% and in the group with XFG were 82%, 70% and 56%, respectively. There was no statistically significant difference in the complete success rates between the patients with POAG and XFG. Conclusion. The primary goal of surgery was to achieve a sufficiently low IOP without additional medication, thus preventing progression of glaucomatous damage. In our study, the complete success in the group with POAG was achieved in 75% and 58% of the patients in the period of 3 and 5 years after surgery, respectively and in the group with XFG complete success was achieved in 70% and 56% of the patients respectively.

XEN implant in primary and secondary open-angle glaucoma: A 12-month retrospective study

2019 ◽  
Vol 30 (5) ◽  
pp. 1034-1041 ◽  
Author(s):  
Ana Ibáñez-Muñoz ◽  
Víctor Santiago Soto-Biforcos ◽  
Leticia Rodríguez-Vicente ◽  
Irune Ortega-Renedo ◽  
María Chacón-González ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Pressure Control ◽  
Pressure Reduction ◽  
Open Angle ◽  
Xen Gel Stent ◽  
Intraocular Pressure Reduction ◽  
Study Population ◽  
Xen Implant

Purpose: The aim of this study was to compare the efficacy and safety of the XEN45 gel stent implant in patients with primary open-angle glaucoma or secondary open-angle glaucoma. Patients and methods: This is a retrospective, single-center, and comparative study conducted in consecutive primary open-angle glaucoma or secondary open-angle glaucoma patients, who underwent a XEN45 implant, alone or in combination with phacoemulsification. The primary end point was the intraocular pressure at the end of the follow-up period. Complete success was defined as an intraocular pressure reduction of ⩾20% from baseline to month 12 without antiglaucoma treatment. Results: Of the 69 patients (74 eyes) who were screened, 68 patients (73 eyes) were included in this study. In the overall study population, XEN gel stent significantly reduced intraocular pressure from 22.3 (21.0–23.5) mmHg at baseline to 15.3 (14.3–16.3) mmHg, p < 0.0001. As compared to baseline, mean intraocular pressure reduction was –7.3 (−9.7 to −5.0) and –6.6 (−8.4 to −4.8) mmHg in the primary open-angle glaucoma and secondary open-angle glaucoma groups, respectively, p = 0.6357. At month 12, 53 (72.6%) eyes were classified as success. The mean number of antiglaucoma medications was significantly reduced in both groups ( p < 0.0001, each). Complications included anterior chamber flattening (one eye), XEN implant extrusion (four eyes), one of whom had an endophthalmitis that required vitrectomy, and one eye underwent a trabeculectomy due to inadequate intraocular pressure control. Conclusion: XEN gel stent, either alone or in combination with phacoemulsification, provided a significant reduction in both intraocular pressure and medical antiglaucoma treatment, but with some safety concerns, in a cohort of patients with open-angle glaucoma (primary or secondary).

24-Hour Intraocular Pressure Control Obtained with Evening- versus Morning-Dosed Travoprost in Primary Open-Angle Glaucoma

Ophthalmology ◽  
2006 ◽  
Vol 113 (3) ◽  
pp. 446-450 ◽  
Author(s):  
Anastasios G.P. Konstas ◽  
Dimitrios Mikropoulos ◽  
Kostantinos Kaltsos ◽  
Jessica N. Jenkins ◽  
William C. Stewart
Keyword(s):  
Intraocular Pressure ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Pressure Control ◽  
Open Angle
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