Study of drug susceptibility pattern of mycobacterium tuberculosis samples from known cases of extrapulmonary tuberculosis samples in Mumbai city

2021 ◽  
Vol 17 (2) ◽  
pp. 20-25
Author(s):  
Ashima Jamwal ◽  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Extrapulmonary Tuberculosis ◽  
Drug Susceptibility ◽  
Susceptibility Pattern ◽  
Drug Susceptibility Pattern ◽  
Mumbai City

scholarly journals A First Insight into the Genetic Diversity and Drug Susceptibility Pattern of Mycobacterium tuberculosis Complex in Zhejiang, China

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Zhengwei Liu ◽  
Yu Pang ◽  
Songhua Chen ◽  
Beibei Wu ◽  
Haibo He ◽  
...  
Keyword(s):  
Genetic Diversity ◽  
Drug Resistance ◽  
Mycobacterium Tuberculosis ◽  
Drug Susceptibility ◽  
Beijing Genotype ◽  
Susceptibility Pattern ◽  
Significant Difference ◽  
Drug Susceptibility Pattern ◽  
Susceptibility Profiles ◽  
First Time

In this study, our aim was to determine the predominant genotypes among the Mycobacterium tuberculosis (MTB) strains circulating in Zhejiang Province. In addition, we also sought to determine the potential associations between MTB genotypes and susceptibility to first-line drugs. Out of these isolates, 673 (71.6%) were classified into the Beijing genotype, while the other 267 (28.4%) were from non-Beijing families. The highest proportion of Beijing genotype was found in Huzhou (80.0%) and the lowest in Lishui (48.3%). Statistical analysis revealed that there was a significant difference in the prevalence of Beijing genotype among different regions (χ2 = 17.57, P = 0.04). In addition, the overall proportions of drug resistance to INH, RIF, SM, and EMB were 13.2% (124/940), 21.8% (75/940), 3.4% (32/940), and 5.9% (55/940) in Zhejiang, respectively. Further comparison revealed that there was no significant difference in drug susceptibility profiles between Beijing and non-Beijing strains (P > 0.05). In conclusion, we describe the genetic diversity and drug susceptibility pattern of MTB in Zhejiang for the first time. Our data demonstrate that Beijing genotype is the predominant lineage in Zhejiang, while the distribution of Beijing-genotype strains shows geographic diversity. In addition, no correlation is observed between Beijing genotype and anti-TB drug resistance.

scholarly journals Yeast Colonization and Drug Susceptibility Pattern in the Pediatric Patients With Neutropenia

1970 ◽  
Vol 7 (8) ◽  
Author(s):  
Pedram Haddadi ◽  
Soheila Zareifar ◽  
Parisa Badiee ◽  
Abdolvahab Alborzi ◽  
Maral Mokhtari ◽  
...  
Keyword(s):  
Pediatric Patients ◽  
Drug Susceptibility ◽  
Susceptibility Pattern ◽  
Drug Susceptibility Pattern
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