scholarly journals Association of nitrotyrosine with oxidised LDL, C- reactive protein and malondialdehyde in prehypertensive and hypertensive patients

2019 ◽  
Vol 12 (2) ◽  
pp. 56-61
Author(s):  
Balu Mahendran K ◽  
◽  
Santhi T ◽  
2012 ◽  
Vol 12 (1) ◽  
Author(s):  
Manuel A Gomez-Marcos ◽  
Jose I Recio-Rodríguez ◽  
Maria C Patino-Alonso ◽  
Cristina Agudo-Conde ◽  
Leticia Gomez-Sanchez ◽  
...  

2019 ◽  
Vol 20 (3) ◽  
pp. 147032031986889 ◽  
Author(s):  
Piotr Ruszkowski ◽  
Anna Masajtis-Zagajewska ◽  
Michał Nowicki

Background: The aim of this study was to compare the influence of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors on endothelial function and blood pressure in patients with essential hypertension on long-term angiotensin-converting enzyme inhibitor therapy. Method: The study was designed as a prospective, double-blind, randomised, placebo controlled, crossover clinical trial. Twenty patients with essential hypertension were treated with an angiotensin-converting enzyme inhibitor; the control group included 10 healthy subjects. Hypertensive patients received in random order 80 mg of fluvastatin daily or placebo for 6 weeks. The following parameters were assessed at baseline and after each treatment period: serum lipids, flow-mediated vasodilation, activity of von Willebrand factor, concentration of vascular endothelial growth factor, C-reactive protein and 24-hour blood pressure profile. Results: Hypertensive patients did not differ from healthy subjects with respect to age, body mass and biochemical parameters, with the exception of C-reactive protein, which was higher in hypertensive patients ( P=0.02). After statin therapy, low-density lipoprotein cholesterol ( P<0.0001), C-reactive protein ( P=0.03), von Willebrand factor ( P=0.03) and vascular endothelial growth factor ( P<0.01) decreased and flow-mediated vasodilation improved ( P<0.001). Statins had no significant effect on blood pressure. Conclusions: Statins added to angiotensin-converting enzyme inhibitors may improve endothelial function and ameliorate inflammation independently of blood pressure.


2020 ◽  
Author(s):  
Raffaele Maio ◽  
Maria Perticone ◽  
Edoardo Suraci ◽  
Angela Sciacqua ◽  
Giorgio Sesti ◽  
...  

2005 ◽  
Vol 19 (7) ◽  
pp. 521-526 ◽  
Author(s):  
M J Hommels ◽  
A J A M van der Ven ◽  
A A Kroon ◽  
A G H Kessels ◽  
M P van Dieijen-Visser ◽  
...  

2004 ◽  
Vol 22 (Suppl. 2) ◽  
pp. S217
Author(s):  
C. Tsioufis ◽  
K. Dimitriadis ◽  
M. Toutouza ◽  
D. Chatzis ◽  
C. Vasiliadou ◽  
...  

2004 ◽  
Vol 22 (Suppl. 2) ◽  
pp. S327-S328
Author(s):  
K. Dimitriadis ◽  
C. Tsioufis ◽  
M. Toutouza ◽  
D. Chatzis ◽  
E. Taxiarchou ◽  
...  

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