scholarly journals Impact of Antibody Cocktail Therapy Combined with Casirivimab and Imdevimab on Clinical Outcome for Covid-19 patients in A Real-Life Setting: A Single Institute Analysis

2021 ◽  
Vol 04 (04) ◽  
Author(s):  
Yasutaka Kakinoki, ◽  
Kazuki Yamada, ◽  
Yoko Tanino, ◽  
Keiko Suzuki, ◽  
Takaya Ichikawa, ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Real Life ◽  
Real Life Setting ◽  
Antibody Cocktail

102 Clinical outcome in patients treated with Nobori, a new generation drug eluting stents in a real life setting: Abstract 102 Table 1

Heart ◽  
2010 ◽  
Vol 96 (Suppl 1) ◽  
pp. A60-A60
Author(s):  
F Fath-Ordoubadi ◽  
N West ◽  
S Talwar ◽  
F Witherow ◽  
D Hildick-Smith ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Real Life ◽  
Drug Eluting Stents ◽  
Real Life Setting ◽  
Drug Eluting ◽  
New Generation

scholarly journals Treatment with 5-Azacytidine improves clinical outcome in high-risk MDS patients in the ‘real life’ setting: A single center observational study

Hematology ◽  
2015 ◽  
Vol 21 (1) ◽  
pp. 34-41 ◽  
Author(s):  
Sotirios G. Papageorgiou ◽  
Diamantina Vasilatou ◽  
Christos K. Kontos ◽  
Periklis Foukas ◽  
Maria Kefala ◽  
...  
Keyword(s):  
High Risk ◽  
Clinical Outcome ◽  
Observational Study ◽  
Real Life ◽  
Single Center ◽  
The Real ◽  
Real Life Setting ◽  
Single Center Observational Study

scholarly journals Impact of Antibody Cocktail Therapy Combined with Casirivimab and Imdevimab on Clinical Outcome for Covid-19 patients in A Real-Life Setting: A Single Institute Analysis

2021 ◽  
Author(s):  
Yasutaka Kakinoki ◽  
Kazuki Yamada ◽  
Yoko Tanino ◽  
Keiko Suzuki ◽  
Takaya Ichikawa ◽  
...  
Keyword(s):  
Risk Factors ◽  
High Risk ◽  
Severe Disease ◽  
Real Life ◽  
Public Health Care ◽  
Medical Interventions ◽  
High Risk Factors ◽  
Real Life Setting ◽  
Medical Facilities ◽  
Antibody Cocktail

ABSTRACT Background. Recent data from clinical trial suggest that antibody cocktail therapy, a combination of the monoclonal antibodies casirivimab and imdevimab, has been shown to rapidly reduce the viral load and markedly decrease the risk of hospitalization or death among high-risk patients with coronavirus disease 2019 (Covid-19). However, it remains unclear how effective in a real-life clinical setting the therapy is. Methods. We retrospectively analyzed mild to moderate Covid-19 patients with one or more high-risk factors for severe disease who consecutively underwent the antibody cocktail therapy of the disease in our institute in June 2021 through early September 2021, compared to those with high-risk factors who were isolated in non-medical facilities consecutively during the same period, thereby being not given the antibody cocktail therapy there. The key outcome was the percentage of patients with Covid-19-related deterioration which needed additional medical interventions, such as oxygen support or other antiviral therapies. Results. Data from 55 patients with initially receiving antibody cocktail therapy and 53 patients with isolation into non-medical facilities are analyzed. 22 (41.5 %) of 53 patients with isolation facilities were finally hospitalized to receive medical interventions. On the other hand, 13 (23.6 %) of 55 patients with antibody cocktail therapy in our hospital subsequently underwent further medical interventions because of the progression. In multivariate analysis with variables of age, BMI, and high-risk factors, the antibody cocktail therapy significantly reduced 70 % in the need for further medical interventions compared to the initial isolation in the non-medical facilities (odds ratio=0.30, 95%CI [0.10-0.87], p=0.027). Furthermore, patients with 96% or above of SPO2 were significantly more favorable for the therapy than those with 95% or below of SPO2. Conclusion. The treatment of antibody cocktail was closely linked to reduction in the need for further medical interventions. The result indicates that the antibody cocktail therapy is associated with reducing the strain on hospitals, which is related to the improvement of medical management for public health care in Covid-19 pandemic era.

MANAGEMENT OF RESECTION OF LARGE COLONIC LESIONS IN A REAL-LIFE SETTING: THE SCALP STUDY

2018 ◽  
Author(s):  
A Amato ◽  
F Radaelli ◽  
V Cennamo ◽  
E Di Giulio ◽  
L Fuccio ◽  
...  
Keyword(s):  
Real Life ◽  
Real Life Setting

130-LB: Retrospective Evaluation of Treatment Patterns in a Real-Life Setting Environment with Dapagliflozin or DPP-4 Inhibitors as Add-On Therapy in Uncontrolled DM2 Patients Who Previously Failed on Other Regimens

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 130-LB
Author(s):  
DIEGO ESPINOZA-PERALTA ◽  
ARNULFO GONZÁLEZ-CANTÚ ◽  
ALEJANDRA I. SILVA ◽  
JUAN G. COLLADO ◽  
JORGE DAVID ROGEL-MANZANARES ◽  
...  
Keyword(s):  
Real Life ◽  
Treatment Patterns ◽  
Retrospective Evaluation ◽  
Real Life Setting
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