Clinical Management of Unusual Configuration in a Lower Second Molar with Four Roots - 2 Years Follow Up

2021 ◽  
Vol 04 (03) ◽  
Author(s):  
Ghadah A Altaroti ◽  
Khalaf A Alwasi ◽  
Raif R Marqoshi ◽  
Tarek Ezzeldin
Keyword(s):  
Clinical Management ◽  
Second Molar

scholarly journals Retinoblastoma genetics screening and clinical management

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Himika Gupta ◽  
Sivasankar Malaichamy ◽  
Ashwin Mallipatna ◽  
Sakthivel Murugan ◽  
Nallathambi Jeyabalan ◽  
...  
Keyword(s):  
Clinical Management ◽  
Detection Rate ◽  
Mutation Detection ◽  
Gene Mutations ◽  
Disease Recurrence ◽  
Germline Mutations ◽  
Global Studies ◽  
Mutation Detection Rate ◽  
Gene Deletions

Abstract Background India accounts for 20% of the global retinoblastoma (RB) burden. However, the existing data on RB1 gene germline mutations and its influence on clinical decisions is minimally explored. Methods Fifty children with RB underwent complete clinical examination and appropriate multidisciplinary management. Screening of germline RB1 gene mutations was performed through next-generation sequencing and Multiplex Ligation-dependent Probe Amplification (MLPA) analysis. The mutation and non-mutation groups were compared for clinical parameters especially severity, progression and recurrence. Results Twenty-nine patients had bilateral RB (BLRB) and 21 had unilateral RB (ULRB). The genetic analysis revealed 20 RB1 variations in 29 probands, inclusive of 3 novel mutations, known 16 mutations and heterozygous whole gene deletions. The mutation detection rate (MDR) was 86.2% in BLRB and 19% in ULRB. Associations of disease recurrence (p = 0.021), progression (p = 0.000) and higher percentage of optic nerve invasion, subretinal seeds and high-risk pathological factors were observed in the mutation group. Clinical management was influenced by the presence of germline mutations, particularly while deciding on enucleation, frequency of periodic follow up and radiotherapy. Conclusions We identified novel RB1 mutations, and our mutation detection rate was on par with the previous global studies. In our study, genetic results influenced clinical management and we suggest that it should be an essential and integral component of RB-care in India and elsewhere.

Early diagnosis, clinical management, and follow-up of cardiovascular events with ponatinib

2020 ◽  
Vol 25 (3) ◽  
pp. 447-456 ◽  
Author(s):  
Grazia Casavecchia ◽  
Maurizio Galderisi ◽  
Giuseppina Novo ◽  
Matteo Gravina ◽  
Ciro Santoro ◽  
...  
Keyword(s):  
Early Diagnosis ◽  
Clinical Management ◽  
Cardiovascular Events

Paroxetine in panic disorder: clinical management and long-term follow-up

2004 ◽  
Vol 4 (2) ◽  
pp. 191-198 ◽  
Author(s):  
Pinhas N Dannon ◽  
Katherine Lowengrub ◽  
I Iancu ◽  
Moshe Kotler
Keyword(s):  
Panic Disorder ◽  
Clinical Management ◽  
Long Term Follow Up

scholarly journals Radicular Perforation Repair with Mineral Trioxide Aggregate: A Case Report with 10-Year Follow-up

2016 ◽  
Vol 10 (1) ◽  
pp. 733-738 ◽  
Author(s):  
Leopoldo Cosme-Silva ◽  
Breno Carnevalli ◽  
Vivien Thiemy Sakai ◽  
Naiana Viana Viola ◽  
Leon Franco de Carvalho ◽  
...  
Keyword(s):  
Case Report ◽  
Root Canal ◽  
Mineral Trioxide Aggregate ◽  
Radiographic Examination ◽  
Root Canal Filling ◽  
Second Molar ◽  
Iatrogenic Perforation ◽  
Iatrogenic Complications ◽  
Root Canal Retreatment

Background: Iatrogenic complications such as accidental perforation of the root or the floor of the pulp chamber may occur. Case Report: Patient was referred for root canal retreatment of the mandibular left second molar with periapical lesion evidenced through radiographic examination. During post removal, iatrogenic perforation occurred at the mesial face of the distal root. After clinical localization of the perforation and bleeding control, MTA was applied. In a second appointment, the root canal filling was removed and the chemical-surgical retreatment of the canals was performed, followed by the obturation with gutta-percha and sealer. Patient returned after three days reporting no pain. After 6 months, 3, 7 and 10 years of follow-up. Conclusion: Absence of pain, normal periodontal probing and lack of radiolucent area at the region of perforation and the periapices were detected, which evidenced the successful repair of the tooth.

Clinical Management Protocol for Dental Implants Inserted in Patients with Active Lichen Planus. Part II 4‐Year Follow‐Up

2018 ◽  
Vol 28 (5) ◽  
pp. 519-525 ◽  
Author(s):  
Aya Khamis Khamis ◽  
Moustafa Nabil Aboushelib ◽  
Mohamed Hamdy Helal
Keyword(s):  
Dental Implants ◽  
Lichen Planus ◽  
Clinical Management ◽  
Management Protocol

scholarly journals ISMAR-study presentation: in-hospital epidemiology and clinical management of respiratory and cardiac comorbidities in cardiac and respiratory disease units

2014 ◽  
Vol 9 ◽  
Author(s):  
Roberto Tramarin ◽  
Mario Polverino ◽  
Maurizio Volterrani ◽  
Bruna Girardi ◽  
Claudio Chimini ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Clinical Management ◽  
Real Life ◽  
Length Of Hospital Stay ◽  
Relevant Information ◽  
Hospital Epidemiology ◽  
Discharge Data ◽  
Definition Of ◽  
Current Guidelines

Background: Cardiovascular and respiratory diseases are leading causes of morbidity and their co-occurrence has important implications in mortality and other outcomes. Even the most recent guidelines do not reliably address clinical, prognostic, and therapeutic concerns due to the overlap of respiratory and cardiac diseases. Study objectives and design: In order to evaluate in the reality of clinical practice the epidemiology and the reciprocal impact of cardio-pulmonary comorbidity on the clinical management, diagnostic workup and treatment, 1,500 cardiac and 1,500 respiratory inpatients, admitted in acute and rehabilitation units, will be enrolled in a multicenter, nationwide, prospective observational study. For this purpose, each center will enroll at least 50 consecutive patients. At discharge, data analysis will be aimed at the definition of cardiac and pulmonary inpatient comorbidity prevalence, demographic characteristics, length of hospital stay, and risk factors, taking into account also procedures, pharmacological and non-pharmacological treatment, and follow up in patients with cardio-respiratory comorbidity. Conclusions: The purely observational design of the study aims to give new relevant information on the assessment and management of overlapping patients in real life clinical practice, and new insight for improvement and implementation of current guidelines on the management of individual diseases.

Efficacy of extended clinical management, group CBT, and group plus individual CBT for major depression: Results of a two-year follow-up study

2018 ◽  
Vol 238 ◽  
pp. 570-578 ◽  
Author(s):  
Annette Schaub ◽  
Ulrich Goldmann ◽  
T Kim Mueser ◽  
Stephan Goerigk ◽  
Martin Hautzinger ◽  
...  
Keyword(s):  
Major Depression ◽  
Clinical Management ◽  
Follow Up Study ◽  
Management Group ◽  
Group Cbt
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