scholarly journals Evidence for Cows' Minds and Hearts: Why Cows Are Far More than Biological Machines

2017 ◽  
Vol 4 (4) ◽  
pp. 512-514
Author(s):  
Barbara King
Keyword(s):  
Biological Machines

Molecular Biological Machines

2003 ◽  
pp. 277-318
Author(s):  
Jack A. Tuszynski ◽  
Michal Kurzynski
Keyword(s):  
Biological Machines

scholarly journals Computationally assisted design and selection of maneuverable biological walking machines

2020 ◽  
Author(s):  
Jiaojiao Wang ◽  
Junehu Park ◽  
Xiaotian Zhang ◽  
Insu Park ◽  
Evin Kilicarslan ◽  
...  
Keyword(s):  
Robot Design ◽  
Systematic Design ◽  
Forward Motion ◽  
Modeling Simulation ◽  
Walking Machines ◽  
Biological Machines ◽  
Muscle Actuators ◽  
Computational Predictions ◽  
Selection Of ◽  
Dual Ring

ABSTRACTThe intriguing opportunities enabled by the use of living components in biological machines have spurred the development of a variety of muscle-powered bio-hybrid robots in recent years. Among them, several generations of bio-hybrid walkers have been established as reliable platforms to study untethered locomotion. However, despite these advances, such technology is not mature yet, and major challenges remain. This study takes steps to address two of them: the lack of systematic design approaches, common to bio-hybrid robotics in general, and in the case of bio-hybrid walkers specifically, the lack of maneuverability. We then present here a dual-ring biobot, computationally designed and selected to exhibit robust forward motion and rotational steering. This dual-ring biobot consists of two independent muscle actuators and a 4-legged scaffold asymmetric in the fore/aft direction. The integration of multiple muscles within its body architecture, combined with differential electrical stimulation, allows the robot to maneuver. The dual-ring robot design is then fabricated and experimentally tested, confirming computational predictions and turning abilities. Overall, our design approach based on modeling, simulation, and fabrication exemplified in this robot represents a route to efficiently engineer biological machines with adaptive functionalities.

scholarly journals Molecular machines with bio-inspired mechanisms

2018 ◽  
Vol 115 (38) ◽  
pp. 9397-9404 ◽  
Author(s):  
Liang Zhang ◽  
Vanesa Marcos ◽  
David A. Leigh
Keyword(s):  
Molecular Level ◽  
Molecular Machines ◽  
Natural Processes ◽  
Present Generation ◽  
Biological Machines

The widespread use of molecular-level motion in key natural processes suggests that great rewards could come from bridging the gap between the present generation of synthetic molecular machines—which by and large function as switches—and the machines of the macroscopic world, which utilize the synchronized behavior of integrated components to perform more sophisticated tasks than is possible with any individual switch. Should we try to make molecular machines of greater complexity by trying to mimic machines from the macroscopic world or instead apply unfamiliar (and no doubt have to discover or invent currently unknown) mechanisms utilized by biological machines? Here we try to answer that question by exploring some of the advances made to date using bio-inspired machine mechanisms.

scholarly journals Theoretical perspectives on biological machines

2020 ◽  
Vol 92 (2) ◽  
Author(s):  
Mauro L. Mugnai ◽  
Changbong Hyeon ◽  
Michael Hinczewski ◽  
D. Thirumalai
Keyword(s):  
Theoretical Perspectives ◽  
Biological Machines

scholarly journals ARE CHILDREN BETTER ???BIOLOGICAL MACHINES??? THAN ADULTS?

2001 ◽  
Vol 33 (5) ◽  
pp. S1
Author(s):  
Marco E. Cabrera ◽  
Oded Bar-Or ◽  
M E. Cabrera ◽  
O Bar-Or ◽  
Alberto E. Minetti ◽  
...  
Keyword(s):  
Biological Machines

scholarly journals Investigating the Life Expectancy and Proteolytic Degradation of Engineered Skeletal Muscle Biological Machines

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Caroline Cvetkovic ◽  
Meghan C. Ferrall-Fairbanks ◽  
Eunkyung Ko ◽  
Lauren Grant ◽  
Hyunjoon Kong ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Life Expectancy ◽  
Proteolytic Degradation ◽  
Biological Machines

Unscrambling the puzzle of biological machines: The importance of the details

Cell ◽  
1992 ◽  
Vol 68 (3) ◽  
pp. 415-420 ◽  
Author(s):  
Bruce Alberts ◽  
Ryn Miake-Lye
Keyword(s):  
Biological Machines

scholarly journals Cells into Systems

2010 ◽  
Vol 132 (11) ◽  
pp. 30-34 ◽  
Author(s):  
Roger D. Kamm ◽  
Robert M. Nerem ◽  
K. Jimmy Hsia
Keyword(s):  
Real World ◽  
Scientific Discipline ◽  
Cellular Systems ◽  
Health Security ◽  
Emergent Systems ◽  
Different Types ◽  
Biological Machines ◽  
Engineered Systems ◽  
Emergent Behaviors ◽  
Real World Problems

This article focuses on different research efforts of Emergent Behaviors of Integrated Cellular Systems (EBICS) for creating biological machines. EBICS’s mission is to create a new scientific discipline for building living, multicellular machines that solve real-world problems in health, security, and the environment. The goal of building biological machines may be achieved through either of two distinct pathways— engineered systems and emergent systems—and the distinctions between them are important and fundamental. While a great deal of progress has been made developing the components for biological machines, one key challenge is the limited understanding of how cells interact with each other and with their environment. In order to create a biological machine, engineers will need to understand the language that cells of different types use to communicate with each other. Biological machines of the future will encompass the complexities of nature, the intricacies of which we are just beginning to comprehend.

scholarly journals Living Machines

2017 ◽  
Vol 139 (06) ◽  
pp. 44-47
Author(s):  
Monique Brouillette
Keyword(s):  
Cell Types ◽  
Genetically Engineered ◽  
Cellular Systems ◽  
World Health ◽  
Reverse Engineer ◽  
Biological Machines ◽  
3D Printed ◽  
Human Joints ◽  
Different Cell Types ◽  
Emergent Behaviors

This article provides an insight into National Science Foundation (NSF) funded research and development of biological machines. The goal of these research projects is to build living, multicellular machines that sense, move, and solve real-world health problems. One of the Emergent Behaviors of Integrated Cellular Systems (EBICS) group has developed a biobot that walks. Inspired by the structure of human joints, this walker has two short, stubby legs connected by a bridge. The skeleton is constructed from a soft Jell-O-like 3D-printed skeleton called hydrogel, and surrounded by a band of skeletal muscle. The group genetically engineered the cells to produce a protein called channel rhodopsin, a sensory photorecepter that enables the muscle to contract in response to blue light. This provides an easy on–off switch to activate the muscle spurring the bot to move its legs and walk. As biologists understand better how tissues develop, bioengineers will be able to reverse-engineer development to better program cells to self-assemble to create biological machines. Plans for future bots include different cell types and many more functionalities.

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