scholarly journals Neutrophil-lymphocyte ratio and mean platelet volume as predictive factors for liver fibrosis and steatosis in patients with chronic hepatitis B

2018 ◽  
Vol 25 (4) ◽  
pp. 690-692 ◽  
Author(s):  
Agnieszka Pokora Rodak ◽  
Sławomir Kiciak ◽  
Krzysztof Tomasiewicz
Keyword(s):  
Chronic Hepatitis ◽  
Liver Fibrosis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Predictive Factors ◽  
Mean Platelet Volume ◽  
Platelet Volume ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio

Can mean platelet volume determine the severity of liver fibrosis or inflammation in patients with chronic hepatitis B?

2013 ◽  
Vol 25 (5) ◽  
pp. 606-612 ◽  
Author(s):  
Bahadir Ceylan ◽  
Muzaffer Fincanci ◽  
Cem Yardimci ◽  
Gülhan Eren ◽  
Ümit Tözalgan ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Liver Fibrosis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Mean Platelet Volume ◽  
Platelet Volume

scholarly journals Predictive Performances of Blood Parameter Ratios for Liver Inflammation and Advanced Liver Fibrosis in Chronic Hepatitis B Infection

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Rongrong Ding ◽  
Xinlan Zhou ◽  
Dan Huang ◽  
Yanbing Wang ◽  
Xiufen Li ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Liver Fibrosis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Predictive Accuracy ◽  
Liver Histology ◽  
Blood Parameter ◽  
Liver Inflammation ◽  
Operating Characteristics ◽  
Lymphocyte Ratio

Objective. Blood parameter ratios, including neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), and monocyte to lymphocyte ratio (MLR), have been reported that they are correlated to the progression of liver disease. This study is aimed at evaluating the predictive value of PLR, NLR, and MLR for liver inflammation and fibrosis in patients with chronic hepatitis B (CHB). Methods. We recruited 457 patients with CHB who underwent a liver biopsy and routine laboratory tests. Liver histology was assessed according to the Scheuer scoring system. The predictive accuracy for liver inflammation and fibrosis was assessed by receiver operating characteristics (ROC) analysis. Results. PLR and NLR presented significantly reverse correlation to liver inflammation and fibrosis. However, these correlations were not observed for MLR and liver histology. The AUROCs of PLR for assessing G2-3 and G3 were 0.676 and 0.705 with cutoffs 74.27 and 68.75, respectively. The AUROCs of NLR in predicting inflammatory scores G2-3 and G3 were 0.616 and 0.569 with cutoffs 1.36 and 1.85, respectively. The AUROCs of PLR for evaluating fibrosis stages S3-4 and S4 were 0.723 and 0.757 with cutoffs 79.67 and 74.27, respectively. The AUROCs of NLR for evaluating fibrosis stages S3-4 and S4 were 0.590 with cutoff 1.14. Conclusion. Although PLR has similar predictive power of progressive liver fibrosis compared with APRI, FIB-4, and GPR in CHB patients, it has the advantage of less cost and easy application with the potential to be widely used in clinical practice.

scholarly journals Mean platelet volume as a fibrosis marker in patients with chronic hepatitis B

2011 ◽  
Vol 25 (3) ◽  
pp. 162-165 ◽  
Author(s):  
Fuat Ekiz ◽  
Osman Yüksel ◽  
Erdem Koçak ◽  
Barış Yılmaz ◽  
Akif Altınbaş ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Mean Platelet Volume ◽  
Platelet Volume ◽  
Fibrosis Marker
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