scholarly journals Morphological Changes in the Lingual Papillae and Their Connective Tissue Cores on the 7,12-dimethylbenz[.ALPHA.]anthracene (DMBA) stimulated Rat Experimental Model

2009 ◽  
Vol 85 (4) ◽  
pp. 129-137 ◽  
Author(s):  
Jinhua ZHENG ◽  
Liping XIE ◽  
He TENG ◽  
Shilong LIU ◽  
Ken YOSHIMURA ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Experimental Model ◽  
Morphological Changes ◽  
Lingual Papillae

scholarly journals Porcine liver: experimental model for the intra-hepatic glissonian approach

2008 ◽  
Vol 23 (2) ◽  
pp. 204-207 ◽  
Author(s):  
Antonio Cavalcanti de Albuquerque Martins ◽  
Marcel Autran Cesar Machado ◽  
Álvaro Antonio Bandeira Ferraz
Keyword(s):  
Connective Tissue ◽  
Experimental Model ◽  
Histological Examination ◽  
Microscopic Examination ◽  
Training Model ◽  
Anatomical Landmarks ◽  
Porcine Liver ◽  
Histological Preparation ◽  
Glissonian Approach ◽  
And Training

PURPOSE: The aim of the study is to evaluate the porcine liver as a teaching and training model for the glissonian approach. METHODS: Ten livers were removed from domestic adult white pigs weighting 35 to 45kg. Based on anatomical landmarks, the glissonian pedicles of each liver segments were dissected and biopsies were taken for histological examination, to analyze the presence of the glissonian sheath. RESULTS: During microscopic examination, a sheath of conjunctive tissue was observed wrapping each segmental pedicle in porcine liver. This could be clearly seen when histological preparation for connective tissue was obtained (Masson technique). CONCLUSION: The morphological arrangement of glissonian pedicles in porcine liver makes this model a useful tool for training the intra-hepatic glissonian approach.

scholarly journals Hormones of thyroid gland in sera of rats treated with different dose of concentrated potassium iodine solutions

2010 ◽  
Vol 138 (5-6) ◽  
pp. 323-327 ◽  
Author(s):  
Ljiljana Markovic ◽  
Violeta Mihailovic-Vucinic ◽  
Jelena Aritonovic
Keyword(s):  
Thyroid Gland ◽  
Genetic Susceptibility ◽  
Experimental Model ◽  
Wistar Rats ◽  
Morphological Changes ◽  
Cell Necrosis ◽  
High Iodine ◽  
Hormone Status ◽  
Potassium Iodine ◽  
Iodine Dose

Introduction Potassium iodine (KI) is used as a drug therapy for treating numerous diseases such as small-vessel vasculitis, erythema nodosum, vasculitis nodularis, Sweet's syndrome, tuberculosis and granulomatosis, and for iodized salt. At the same time, KI can be harmful. Iodine intake may increase the frequency of thyroiditis in humans, and may induce the occurrence of experimental thyroiditis (ET) in animals. Investigations on an experimental model for the examination of thyroiditis in Wistar rats have clearly showed morphological changes in the rat thyroid evoked by KI administration. Objective The purpose of this study was to compare the effects of low and high doses of KI on the thyroid gland of Wistar rats and determine the effect on hormone status (T4, T3 and TSH) in this rat strain. Methods Two groups of rats from the Wistar strain were treated with a low iodine dose (225 ?g/g BW) and with a high iodine dose (675 ?g/g BW) of KI solutions. Untreated nonimmunized animals served as controls. The solution was administrated daily intraperitoneally during the period of 26 consecutive days. Results Monitoring hormone status (TSH, T3 and T4) and morphological changes it was found that therapeutic doses of KI applied in treatment induced the occurrence of experimental thyroiditis (chronic destructive Hashimoto's thyroiditis in humans) and cell necrosis in animals not carrying a genetic susceptibility. Significant inflammatory changes were observed in rats treated with a high iodine dose. Conclusion The early iodine induced cell necrosis and inflammation in the nonimmunized animals without genetic susceptibility is a new experimental model of thyroiditis. .

scholarly journals Histomorphological changes in the rat pancreas after methionine administration

2020 ◽  
Keyword(s):  
Connective Tissue ◽  
Functional Activity ◽  
Morphological Changes ◽  
Pancreatic Tissue ◽  
European Convention ◽  
Standard Diet ◽  
Cell Nuclei ◽  
Ether Anesthesia ◽  
Rat Pancreas ◽  
Histomorphological Changes

The effectiveness of using various methionine preparations for activating pancreatic function is ambiguous; the reasons may include differences in dosage and duration of methionine administration. The question remains, in what extent the methionine application is efficacious for increasing functional activity of a healthy pancreas. The aim of our study was to investigate morphological changes in pancreas after prolonged administration of methionine. The experiments were carried out on 24 males of Wistar rats at the age of 15 months. During 21 days, the experimental animals received methionine at a daily dose of 250 mg/kg of body weight in addition to the standard diet. Histological preparations were made from pancreatic tissue according to standard method. Morphometry was performed using the computer program «Image J». The rats were taken out of the experiment under ether anesthesia. The studies were carried out in accordance with the provisions of the "European Convention for the Protection of Vertebrate Animals used for Experimental and Other Scientific Purposes" (Strasbourg, 1986). Upon completion of the experiment, histomorphological sings of an increase in functional activity were registered in both exocrine (enlarged acini’s areas and their epithelium height, higher nuclear-cytoplasmic ratio of exocrinocytes, and higher number of nucleoli in cell nuclei) and endocrine (enlarged sizes of the Langerhans islets and increased number of endocrinocytes in the islets) parts of the rat pancreas. In the experimental rats, the relative area of ​​the connective tissue and the stromal-parenchyma index of the pancreas, as well as the width of the interlobular and interacinus layers of connective tissue decreased. A decrease in the mass of connective tissue in the pancreas can be considered as one of the signs of its function activation, an improvement in metabolism between acini, and an increase in regenerative capabilities. Thus, additional administration of prophylactic doses of methionine to healthy animals results in distinct morphological signs of increased pancreatic activity.

Structural-morphological changes of the connective tissue of the vaginal mucosa and perineal skin in women with stress urinary incontinence

Urologiia ◽  
2017 ◽  
Vol 5_2017 ◽  
pp. 15-20 ◽  
Author(s):  
V.N. Pavlov Pavlov ◽  
A.G. Yashchuk Yashchuk ◽  
A.A. Kazikhinurov Kazikhinurov ◽  
I.I. Musin Musin ◽  
R.M. Zauinullina Zauinullina ◽  
...  
Keyword(s):  
Urinary Incontinence ◽  
Stress Urinary Incontinence ◽  
Connective Tissue ◽  
Morphological Changes ◽  
Vaginal Mucosa ◽  
Perineal Skin
Sign in / Sign up

Export Citation Format

Share Document