Extraction of inulin using super critical fluid extractor

2021 ◽  
Vol 16 (8) ◽  
pp. 33-37
Author(s):  
Raju Renuka ◽  
Pusparaju Subhapriya ◽  
Kulathooran Ramalakshmi ◽  
Adhiaman Siddhu
Keyword(s):  
Extraction Yield ◽  
Response Surfaces ◽  
Soluble Solids ◽  
Solvent Ratio ◽  
Optimal Conditions ◽  
Fluid Extraction ◽  
Contour Plots ◽  
Conventional Extraction ◽  
Pressure Bar ◽  
The Mathematical Model

Super critical fluid extraction was employed for the extraction of inulin from chicory roots and Response Surface Methodology was used to optimize the effects of processing of extraction yield of inulin considering parameters such as solvent ratio, pressure (bar) and temperature (oC). Tri-dimensional response surfaces and optimal conditions were determined. Contour plots were determined from the mathematical model. In accordance with super critical fluid extraction, maximum inulin yield was obtained as 0.8% at the temperature of 40oC and 100 bar pressure. Conventional extraction technique yields a maximum inulin content of 6.22 % with a solvent ratio of 1:30 at a temperature of 70oC and time 30 mins while the yield of extract (Total soluble solids) was estimated to be 59.09%. Super critical fluid extraction may be used for the extraction of inulin from the roots of chicory for its use as a nutraceutical in functional applications.

Supercritical Fluid Extraction of Genistein from Extruded Soybean

2012 ◽  
Vol 178-181 ◽  
pp. 838-842
Author(s):  
Gui Hua Sheng ◽  
Quan Cheng Zhou
Keyword(s):  
Mathematical Model ◽  
Optimal Condition ◽  
Supercritical Fluid Extraction ◽  
Supercritical Fluid ◽  
Orthogonal Rotation ◽  
Optimal Conditions ◽  
Fluid Extraction ◽  
Model Set ◽  
Experimental Values ◽  
The Mathematical Model

An optimal condition of supercritical fluid extraction (SFE) for genistein in extruded soybean was developed. Optimal conditions through quadratic orthogonal rotation design were verified. The results from SC – CO2 showed that all five experiment factors tested have significant effects on the yield of genistein. The mathematical model set had close agreements with experimental values. It was found that there were 32 optimal extract conditions under which genistein yield higher than 0.092% were gotten through simulate compute. The optimal extracting conditions were stable and recurrable. SC–CO2 had a potential in the extraction of genistein from extruded soybean products.

scholarly journals Optimization of Microwave-Assisted Extraction of Polyphenols from Lemon Myrtle: Comparison of Modern and Conventional Extraction Techniques Based on Bioactivity and Total Polyphenols in Dry Extracts

Processes ◽  
2021 ◽  
Vol 9 (12) ◽  
pp. 2212
Author(s):  
Md Saifullah ◽  
Rebecca McCullum ◽  
Quan Van Vuong
Keyword(s):  
Phenolic Compounds ◽  
Antioxidant Properties ◽  
Extraction Yield ◽  
Solvent Ratio ◽  
Microwave Assisted Extraction ◽  
Extraction Techniques ◽  
Microwave Assisted ◽  
Assisted Extraction ◽  
Conventional Extraction ◽  
Radiation Time

The aromatic herb lemon myrtle is a good source of polyphenols, with high antioxidant and antimicrobial capacity. In this study, the green extraction technique microwave-assisted extraction (MAE) was applied and the extraction parameters were optimized using response surface methodology (RSM) to maximize the extraction yield of phenolic compound and antioxidant properties. Then, it was compared with other popular novel and conventional extraction techniques including ultrasound-assisted extraction (UAE) and shaking water bath (SWB) to identify the most effective technique for extraction of phenolic compounds from lemon myrtle. The results showed that the MAE parameters including radiation time, power, and sample to solvent ratio had a significant influence on the extraction yield of phenolic compounds and antioxidant capacity. The optimal MAE conditions were radiation time of 6 min, microwave power of 630 W, and sample to solvent ratio of 6 g/100 mL. Under optimal conditions, MAE dry extract had similar levels of total phenolic compounds (406.67 ± 8.57 mg GAE/g DW), flavonoids (384.57 ± 2.74 mg CE/g DW), proanthocyanidins (336.54 ± 7.09 mg CE/g DW), antioxidant properties, and antibacterial properties against (Staphylococcus lugdunensis and Bacillus cereus) with the other two methods. However, MAE is eight-times quicker and requires six-times less solvent volume as compared to UAE and SWB. Therefore, MAE is recommended for the extraction of polyphenols from lemon myrtle leaf.

scholarly journals Optimized extraction of polyphenols from leaves of Rosemary (Rosmarinus officinalis L.) grown in Lam Dong province, Vietnam, and evaluation of their antioxidant capacity

2021 ◽  
Vol 19 (1) ◽  
pp. 1043-1051
Author(s):  
Minh-Tam Nguyen-Kim ◽  
Quoc-Cuong Truong ◽  
Minh-Thuy Nguyen ◽  
Bich-Hang Cao-Thi ◽  
Thanh-Danh Tong ◽  
...  
Keyword(s):  
Antioxidant Capacity ◽  
Ethanol Concentration ◽  
Extraction Yield ◽  
Food Preservation ◽  
Solvent Ratio ◽  
Extraction Temperature ◽  
Optimal Conditions ◽  
Polyphenol Content ◽  
Feed Material ◽  
Dried Extract

Abstract In the present study, the optimized solvent extraction conditions with regards to the total polyphenol content (TPC) and antioxidant capacity of rosemary leaf extract (RLE) were determined. The one-factor-at-a-time method was used to independently investigate the effect of several extraction parameters, including ethanol concentration (0–100% v/v), extraction temperature (50–80°C), extraction period (15–60 min), material–solvent ratio (1:5–1:10 g/mL), and extraction cycles (1, 2, and 3 times) on polyphenol content. Response surface methodology (RSM), in combination with a central composite design, was used to perform optimization. The following optimal conditions that gave maximal TPC were determined and experimentally verified: ethanol concentration of 65% (v/v), extraction temperature of 65°C, material–solvent ratio of 1:7.5 g/mL, extraction time of 15 min, and 2 cycles of extraction. These parameters corresponded with the TPC yield of 87.42 ± 0.25 mg gallic acid equivalent/g dried feed material (mg GAE/g DW). The optimal conditions gave a high extraction yield (337 ± 6 mg dried extract/g dried feed material) with 197.28 ± 3.11 mg GAE/g dried extract. The estimated models were strongly significant (p < 0.05) for TPC values with significant regression coefficients (R 2) of 0.9979. The obtained RLE was supposed to be the top grade of natural antioxidant with the IC50 (DPPH assays) value of 9.4 ± 0.1 μg/mL, which is higher than that of the vitamin C by just three times (IC50 = 3.2 ± 0.1 μg/mL). Current results justify RLE as a potential agent in food preservation applications.

Microwave Pretreatment of Vegetable Materials to Increase the Extraction Yield of Natural Products

2018 ◽  
Vol 69 (8) ◽  
pp. 1976-1979
Author(s):  
Ioana Asofiei ◽  
Ioan Calinescu ◽  
Adina Ionuta Gavrila ◽  
Daniel Ighigeanu ◽  
Diana Martin
Keyword(s):  
Natural Products ◽  
Chemical Composition ◽  
Phenolic Compounds ◽  
Total Phenolic Content ◽  
Phenolic Content ◽  
Extraction Yield ◽  
Total Phenolic ◽  
Microwave Pretreatment ◽  
Pretreatment Time ◽  
Conventional Extraction

It was designed and built a laboratory experimental installation (LEI) for the microwave pretreatment of vegetable materials. To study the influence of microwave pretreatment on the total phenolic content (TPC), a conventional extraction of polyphenols from treated and untreated fresh sea buckthorn leaves was performed. For short extraction times, the amount of phenolic compounds was higher for the extracts obtained from treated leaves, but a long pretreatment time (28 s) led to a decrease in TPC. The qualitative analysis showed that the chemical composition is not affected by the microwave pretreatment.

scholarly journals Sub- and Supercritical Extraction of Slovenian Hops (Humulus lupulus L.) Aurora Variety Using Different Solvents

Plants ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 1137
Author(s):  
Katja Bizaj ◽  
Mojca Škerget ◽  
Iztok Jože Košir ◽  
Željko Knez
Keyword(s):  
Sulfur Hexafluoride ◽  
Total Yield ◽  
Extraction Yield ◽  
Operating Conditions ◽  
Influence Of Process Parameters ◽  
Humulus Lupulus L ◽  
Bitter Acids ◽  
Temperature And Pressure ◽  
Carbon Dioxide Co2 ◽  
The Mathematical Model

This work investigates the efficiency of supercritical fluid extraction of hops with a variety of solvents including carbon dioxide (CO2), propane, sulfur hexafluoride (SF6), and dimethyl ether (DME) at various densities (low-density and high-density). Operating parameters were 50 bar, 100 bar and 150 bar and 20 °C, 40 °C, 60 °C and 80 °C for all solvents, respectively. The influence of process parameters on the total yield of extraction and content of bitter acids in the extracts has been investigated. The mathematical model based on Fick’s second law well described the experimental extraction results. Furthermore, HPLC analysis has been used to determine α- and β-acids in extracts. The yield of bitter compounds in hop extracts was largely influenced by the type of solvent, the temperature and pressure applied during extraction. The results show that CO2 and propane were roughly equivalent to DME in solvating power, while SF6 was a poor solvent at the same conditions. The highest yield as well as the highest concentration of bitter acids in extracts were obtained by using DME, where the optimal operating conditions were 40 °C and 100 bar for the extraction of α-acids (max. concentration 9.6%), 60 °C and 50 bar for the extraction of β-acids (4.5%) and 60 °C and 150 bar for the maximum extraction yield (25.6%).

Homogenate Extraction of Dihydroartemisinin from Artemisia Hedinii and Its Antifungal Activity

2021 ◽  
Author(s):  
Cong You ◽  
Jun Yu ◽  
Guangjiong Qin ◽  
JinPeng Yang ◽  
Chunlei Yang ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Crude Extract ◽  
Spore Germination ◽  
Alternaria Alternata ◽  
Low Cost ◽  
Pathogenic Fungi ◽  
Extraction Yield ◽  
Optimal Conditions ◽  
Extraction Technology ◽  
Homogenate Extraction

Abstract Background Artemisia hedinii is a well-known traditional Chinese medicine. It can be used to extract dihydroartemisinin (DHA). Objective The purpose of this study was to explore the optimal conditions for the homogenate extraction of DHA from A. hedinii and the antifungal activity of DHA. Methods In this study, single factor experiments and response surface method were used to determine the optimal extraction conditions of crude extract and DHA, the method of spore germination was used to study the antifungal activity of DHA to Alternaria alternata. Result The optimal conditions were found as fellow: ratio of liquid to material 22 mL/g; Extraction time 60 s; soaking time 34 min. Under these conditions, extraction yield of DHA was (1.76 ± 0.04%). When the concentration of crude extract were 0.5 and 8 mg/mL, the spore germination inhibition rates of Alternaria alternata were (17.00 ± 2.05%) and (92.56 ± 2.01%), which were 3.34 and 1.15 times that of DHA standard, respectively. Conclusion Homogenate extraction technology is a fast and efficient method to extract DHA from A. hedinii. The crude extract has significant antifungal activity against A. alternata with low cost, which provides a possibility for the use of DHA in the prevention and treatment of plant pathogenic fungi. Highlights The optimum conditions of the extraction of DHA from A. hedinii by homogenate extraction were obtained. DHA has antifungal activity against A. alternata. Compared with pure DHA, the crude extract has stronger antifungal activity against A. alternata.

Microwave-Assisted Extraction of Chlorophyll from Filter Mud of Sugercane Mill and Component Analysis

2012 ◽  
Vol 518-523 ◽  
pp. 430-435 ◽  
Author(s):  
Hai Rong Guo ◽  
Shao Ying Ma ◽  
Xiao Fei Wang ◽  
Er Fang Ren ◽  
Yuan Yuan Li
Keyword(s):  
Irradiation Time ◽  
Extraction Time ◽  
Extraction Temperature ◽  
Microwave Assisted Extraction ◽  
Optimal Conditions ◽  
Microwave Assisted ◽  
Assisted Extraction ◽  
Conventional Extraction ◽  
Filter Mud ◽  
Strong Absorption Peak

Microwave-assisted extraction (MAE) was used to extract chlorophylls from filter mud. Ethanol was used as the solvent. The optimal conditions for the MAE of chlorophylls were concluded from the study as the irradiation time, 50 s, the ratio of liquid to solid, 8:1 (mL/g), the extraction temperature, 40 °C, and the extraction time, 60 min. Compared with conventional extraction, the MAE of chlorophylls from the filter mud was more effective. The extraction time for MAE was 60 min with 0.277 mg/g chlorophyll yield, while conventional extraction needed 240 min with only about 0.259 mg/g chlorophyll yield. The Ultraviolet Absorption Spectra of the extracted chlorophylls showed that there was a strong absorption peak at about 663 nm. C=N, Mg-N and C-N was not seen existed from the infrared spectroscopy probably because that the mixed extracts were not purified and the chlorophyll content was less.

Optimization of the Ultrasonic Extraction of Gypenoside III from Gynostemma pentaphyllum by Response Surface Methodology

2012 ◽  
Vol 550-553 ◽  
pp. 1866-1870
Author(s):  
Xiao Dan Tang ◽  
Hai Yang Hang ◽  
Shao Yan Wang ◽  
Jing Xiang Cong
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Extraction Yield ◽  
Raw Material ◽  
Extraction Temperature ◽  
Optimal Conditions ◽  
Gynostemma Pentaphyllum ◽  
Bioactive Component ◽  
Yield Value ◽  
Ultrasonic Time

Gypenosides III is a major bioactive component which is rich in Gynostemma pentaphyllum. For better utilization of the native resource, response surface methodology was used to optimize the extraction conditions of gypenosides III from G. pentaphyllum. The effects of three independent variables on the extraction yield of gypenosides III were investigated and the optimal conditions were evaluated by means of Box-Behnken design. The optimal conditions are as follows: ratio of ethanol to raw material 25, extraction temperature 58°C and ultrasonic time 25min. Under these conditions, the yield of gypenoside III is 1.216±0.05%, which is agreed closely with the predicted yield value.

Modeling of supercritical fluid extraction of flavonoids from Calycopteris floribunda leaves

2014 ◽  
Vol 68 (3) ◽  
Author(s):  
Xiong Liu ◽  
Dong-Liang Yang ◽  
Jia-Jia Liu ◽  
Kuan Xu ◽  
Guo-Hui Wu
Keyword(s):  
Supercritical Fluid Extraction ◽  
Supercritical Fluid ◽  
Extraction Process ◽  
Optimal Conditions ◽  
Fluid Extraction ◽  
Pressure Method ◽  
Organic Solvent Extraction ◽  
Drug Lead ◽  
Temperature And Pressure ◽  
Central Composite

AbstractThe aim of this study was to obtain flavonoids extracts from Calycopteris floribunda leaves using supercritical fluid extraction (SFE) with CO2 and a co-solvent. Pachypodol, a potential anticancer drug lead compound separated from the extracts, was examined. Classical organic solvent extraction (CE) with ethanol was performed to evaluate the high pressure method. HPLC analysis was introduced to interpret the differences between SFE and CE extracts in terms of antioxidant activity and the concentration of pachypodol. SFE kinetics and mathematical modeling of the overall extraction curves (OEC) were investigated. Evaluation of the models against experimental data showed that the Sovová model performs the best. The supercritical fluid extraction process was optimized using a central composite design (CCD), where temperature and pressure were adjusted. The optimal conditions of SFE were: pressure of 30 MPa and temperature of 35°C.

EXPERIMENTAL RESEARCH OF PARTIAL REGULAR MICRORELIEFS FORMED ON ROTARY BODY FACE SURFACES

Aviation ◽  
2021 ◽  
Vol 25 (4) ◽  
pp. 268-277
Author(s):  
Volodymyr Dzyura ◽  
Pavlo Maruschak ◽  
Stoyan Slavov ◽  
Diyan Dimitrov ◽  
Dimka Vasileva
Keyword(s):  
Stochastic Models ◽  
Feed Rate ◽  
Processing Parameters ◽  
Response Surfaces ◽  
Cnc Milling ◽  
Natural Form ◽  
Face Surface ◽  
Contour Plots ◽  
Full Factorial Experimental Design ◽  
Full Factorial

The basic regularities in the influence of processing parameters on the geometrical characteristics of the partially regular microreliefs, formed on the rotary body face surface, are established. Combinations of partially regular microreliefs are formed by using a contemporary CNC milling machine, and an advanced programing method, based on previously developed mathematical models. Full factorial experimental design is carried out, which consist of three factors, varied on three levels. Regression stochastic models in coded and natural form, which give the relations between the width of the grooves and the deforming force, feed rate and the pitch of the axial grooves, are derived as a result. Response surfaces and contour plots are built in order to facilitate the results analysis. Based on the dependencies of the derived regression stochastic models, it is found that the greatest impact on the width of the grooves has the magnitude of the deforming force,followed by the feed rate. Also, it is found that the axial pitch between adjacent toolpaths has the least impact on the width of the grooves. As a result of the full-factorial experiment, the average geometric parameters of the microrelief grooves were obtained on their basis. When used, these values will provide for the required value of the relative burnishing area of the surface with regular microreliefs, and, accordingly, the specified operational properties.

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