scholarly journals Improvement of Lax Skin using a High-Pressure Pneumatic Dermal Delivery System

2016 ◽  
Vol 5 (2) ◽  
pp. 96-100 ◽  
Author(s):  
Ik Jun Moon ◽  
Ji Su Yu ◽  
Won Ah Choi ◽  
Tai Kyung Noh ◽  
Woo Jin Lee ◽  
...  
Keyword(s):  
High Pressure ◽  
Delivery System ◽  
Dermal Delivery

Preparation and characterization of a novel controlled‐release nano‐delivery system loaded with pyraclostrobin via high‐pressure homogenization

2020 ◽  
Vol 76 (8) ◽  
pp. 2829-2837
Author(s):  
Anqi Wang ◽  
Jianxia Cui ◽  
Yan Wang ◽  
Huaxin Zhu ◽  
Ningjun Li ◽  
...  
Keyword(s):  
High Pressure ◽  
Controlled Release ◽  
Delivery System ◽  
High Pressure Homogenization

A rutin nanocrystal gel as an effective dermal delivery system for enhanced anti-photoaging application

2021 ◽  
pp. 1-11
Author(s):  
Jing Li ◽  
Weilong Ni ◽  
Mayinuer Aisha ◽  
Juanjuan Zhang ◽  
Minjie Sun
Keyword(s):  
Delivery System ◽  
Dermal Delivery

High Pressure Turbine Low Radius Radial TOBI Discharge Coefficient Validation Process

2011 ◽  
Author(s):  
A. V. MirzaMoghadam ◽  
A. Riahi ◽  
M. Morris
Keyword(s):  
High Pressure ◽  
Reference Frame ◽  
Delivery System ◽  
Discharge Coefficient ◽  
Pressure Ratio ◽  
Flow Coefficient ◽  
Validation Process ◽  
High Pressure Turbine ◽  
Cold Flow ◽  
Turbine Cooling

A TOBI (tangential on board injection) or preswirl system is a critical component of a high pressure turbine cooling delivery system. Its efficient performance and characterization are critical because the blade and disk life depend on the accuracy of delivering the required flow at the correct temperature and pressure. This paper presents a TOBI flow discharge coefficient validation process applied to a low radius radial configuration starting from a 1D network flow analysis to a 3D frozen rotor CFD analysis of the rotor cooling air delivery system. The analysis domain commences in the combustor plenum stationary reference frame, includes the TOBI, transitions to the rotating reference frame as the flow travels through the rotating cover plate orifice, continues up the turbine disk into the slot bottom blade feed cavity, and terminates in the turbine blade. The present effort includes matching a 1D network model with 3D CFD results using simultaneous goal-matching of pressure predictions throughout the circuit, defining test rig pressure measurements at critical “non-disturbing” locations for quanification of pressure ratio across the TOBI, and finally comparing the TOBI flow coefficient resulting from stationary cold flow tests with what was obtained from the 3D CFD results. Analysis of the results indicates that the discharge coefficient varies with pressure ratio and that the traditional method of using a constant discharge coefficient extracted from a cold flow test run under choked conditions leads to over-predicting turbine cooling flows. TOBI flow coefficient prediction for the present study compares well with the stationary data published by author researchers for the configuration under investigation, and the process described in this paper is general for any TOBI configuration.

High Pressure Turbine Low Radius Radial TOBI Discharge Coefficient Validation Process

2013 ◽  
Vol 135 (7) ◽  
Author(s):  
Alexander V. Mirzamoghadam ◽  
Ardeshir Riahi ◽  
Mark C. Morris
Keyword(s):  
High Pressure ◽  
Reference Frame ◽  
Delivery System ◽  
Discharge Coefficient ◽  
Pressure Ratio ◽  
Flow Coefficient ◽  
Validation Process ◽  
High Pressure Turbine ◽  
Cold Flow ◽  
Turbine Cooling

A TOBI (tangential on board injection), or preswirl, system is a critical component of a high pressure turbine cooling delivery system. Its efficient performance and characterization are critical because the blade and disk life depend on the accuracy of delivering the required flow at the correct temperature and pressure. This paper presents a TOBI flow discharge coefficient validation process applied to a low radius radial configuration starting from a 1dimensional (1D) network flow analysis to a 3 dimensional (3D) frozen rotor computational fluid dynamics (CFD) analysis of the rotor cooling air delivery system. The analysis domain commences in the combustor plenum stationary reference frame, includes the TOBI, transitions to the rotating reference frame as the flow travels through the rotating cover plate orifice, continues up the turbine disk into the slot bottom blade feed cavity, and terminates in the turbine blade. The present effort includes matching a 1D network model with 3D CFD results using simultaneous goal-matching of the pressure predictions throughout the circuit, defining test rig pressure measurements at critical “nondisturbing” locations for quanification of pressure ratio across the TOBI, and finally comparing the TOBI flow coefficient resulting from stationary cold flow tests with what was obtained from the 3D CFD results. An analysis of the results indicates that the discharge coefficient varies with the pressure ratio and that the traditional method of using a constant discharge coefficient extracted from a cold flow test run under choked conditions leads to overpredicting turbine cooling flows. The TOBI flow coefficient prediction for the present study compares well with the stationary data published by otherresearchers for the configuration under investigation and the process described in this paper is general for any TOBI configuration.

scholarly journals Topical gel of Metformin solid lipid nanoparticles: A hopeful promise as a dermal delivery system

2019 ◽  
Vol 175 ◽  
pp. 150-157 ◽  
Author(s):  
Seyyed Sohrab Rostamkalaei ◽  
Jafar Akbari ◽  
Majid Saeedi ◽  
Katayoun Morteza-Semnani ◽  
Ali Nokhodchi
Keyword(s):  
Delivery System ◽  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
Topical Gel ◽  
Solid Lipid ◽  
Dermal Delivery

scholarly journals Topical Gel of Vitamin A Solid Lipid Nanoparticles: A Hopeful Promise as a Dermal Delivery System

2020 ◽  
Author(s):  
Mahshid Boskabadi ◽  
Majid Saeedi ◽  
Jafar Akbari ◽  
Katayoun Morteza-Semnani ◽  
Seyyed Mohammad Hassan Hashemi ◽  
...  
Keyword(s):  
Vitamin A ◽  
Delivery System ◽  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
Topical Gel ◽  
Solid Lipid ◽  
Dermal Delivery
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