Direct and correlated responses to selection in two lines of rabbits selected for feed efficiency under ad libitum and restricted feeding: I. Production traits and gut microbiota characteristics1

2016 ◽  
Vol 94 (1) ◽  
pp. 38-48 ◽  
Author(s):  
L. Drouilhet ◽  
C. S. Achard ◽  
O. Zemb ◽  
C. Molette ◽  
T. Gidenne ◽  
...  
2017 ◽  
Vol 26 (2) ◽  
Author(s):  
Katariina Manni ◽  
Marketta Rinne ◽  
Erkki Joki-Tokola ◽  
Arto Huuskonen

The objective of this study was to determine the effects of restricted feeding strategies on performance of growing and finishing dairy bulls. The feeding experiment comprised in total 32 Finnish Ayrshire bulls with an initial mean live weight (LW) of 122 kg and age of 114 days. Feeding treatments were silage ad libitum and daily barley allowance of 93 g kg-1 LW0.60 (A); restricted feeding (R) at 0.80 × A; increasing feeding (I) similar to R until LW of 430 kg and thereafter similar to A; and decreasing feeding (D) similar to A until LW of 430 kg and thereafter similar to R. Restricted feeding strategies decreased daily dry matter intake and LW gain and increased the time to reach the target carcass weight (300 kg). Bulls on I exhibited compensatory growth. There were no significant differences in feed efficiency between the treatments. The present experiment indicates that silage intake ad libitum and supplemented with concentrate resulted in most effective beef production.


2020 ◽  
Author(s):  
Yuqian Ye ◽  
Haopeng Xu ◽  
Zhibo Xie ◽  
Lun Wang ◽  
Yuning Sun ◽  
...  

Abstract Background: Time-restricted feeding, also known as intermittent fasting, can confer various beneficial effects, especially protecting against obesity and related metabolic disorders, but little is known about the underlying mechanisms. Therefore, the present study aims to investigate the effects of time-restricted feeding on the circadian rhythm of gut microbiota and hepatic metabolism. Methods: Eight-week-old male Kunming mice received either a normal diet ad libitum, a high-fat diet ad libitum, or a high-fat diet restricted to an 8-h temporal window per day for an experimental period of 8 weeks. Weight gain and calorie intake were measured weekly. Serum metabolites, hepatic sections and lipid metabolites, gut microbiota and the hepatic expression of Per1, Cry1, Bmal1, SIRT1, SREBP and PPARα were measured at the end of the experimental period. The composition of gut microbiota and the expression of hepatic genes were compared between four timepoints. Results: Mice that received a time-restricted high-fat diet had less weight gain, milder liver steatosis, and lower hepatic levels of triglycerides than mice that received a high-fat diet ad libitum (p<0.05). The numbers of Bacteroidetes and Firmicutes differed between mice that received a time-restricted high-fat diet and mice that received a high-fat diet ad libitum (p<0.05). Mice fed a time-restricted high-fat diet showed distinct circadian rhythms of hepatic expression of SIRT1, SREBP and PPARα compared with mice fed a normal diet ad libitum, as well as the circadian rhythm of the abundance of Bacteroidetes and Firmicutes. Conclusions: Time-restricted feeding is associated with better metabolic conditions, perhaps owing to alterations in gut microbiota and the circadian pattern of molecules related to hepatic lipid metabolism, which were first to report.


Author(s):  
N.D. Cameron ◽  
M.K. Curran

Genetic improvement in commercially important traits of pigs produced under commercial conditions is generally achieved through selection of parents which are performance tested under special conditions. If pigs are performance tested in one environment and progeny tested in another environment, then the same animals may not be selected on the basis of the two tests, which would result in a genotype-environment interaction. The testing station and commercial unit often have feeding regime (ad-libitum, restricted or both) confounded with environment. This study estimated the genetic correlation between ad-libitum and restricted feeding in one environment for production traits to traits to determine the contribution 6T the genotype-feeding regime interaction to the genotype-environment interaction.


Author(s):  
M.K. Curran ◽  
N.D. Cameron ◽  
J.C. Kerr

Divergent selection lines for lean growth on a restricted feeding regime, in Large White and Landrace pigs, were established to complement the lean growth selection lines on ad-libitum feeding. This study estimated the direct and correlated responses after four generations of selection and the corresponding genetic and phenotypic parameters.The selection objective for lean growth on restricted or scale (LGS) feeding was to obtain equal correlated responses in growth rate and carcass lean content, measured in phenotypic s.d. The selection criterion included measurements of growth rate and ultrasonic backfat depth.Large White (LW) and Landrace (LR) boars and gilts were purchased from eight British nucleus herds and boars from national artificial insemination centres in 1982. Homozygous or heterozygous halothane positive pigs were not included in the experiment. The base populations consisted of 31 LW and 19 LR sires and 57 LW and 67 LR dams. Within each population, there were high and low selection lines with a control line, each consisting of 10 boars and 20 gilts, with a generation interval of 13.5 and 12 months for LW and LR pigs. Animals were performance tested in individual pens from 30±3 kg for a period of 84 days and fed a high energy (13.8 MJ DE/kg DM) and high protein (210 g/kg DM crude protein) pelleted ration. Daily food intake was equal to 0.75 g/g of the daily food intake for ad-libitum fed pigs and the total food intake was 134 kg for LW pigs and 150 kg for LR pigs. On average, 3 boars and 3 gilts were tested per litter. The total number of pigs tested per line and average inbreeding coefficients at generation four, by population are given below.


2020 ◽  
Vol 7 ◽  
Author(s):  
Yuqian Ye ◽  
Haopeng Xu ◽  
Zhibo Xie ◽  
Lun Wang ◽  
Yuning Sun ◽  
...  

Background: Time-restricted feeding, also known as intermittent fasting, can confer various beneficial effects, especially protecting against obesity, and related metabolic disorders, but little is known about the underlying mechanisms. Therefore, the present study aims to investigate the effects of time-restricted feeding on the circadian rhythm of gut microbiota and hepatic metabolism.Methods: Eight-week-old male Kunming mice received either a normal diet ad libitum, a high-fat diet ad libitum, or a high-fat diet restricted to an 8-h temporal window per day for an experimental period of 8 weeks. Weight gain and calorie intake were measured weekly. Serum metabolites, hepatic sections and lipid metabolites, gut microbiota, and the hepatic expression of Per1, Cry1, Bmal1, SIRT1, SREBP, and PPARα were measured at the end of the experimental period. The composition of gut microbiota and the expression of hepatic genes were compared between four timepoints.Results: Mice that received a time-restricted high-fat diet had less weight gain, milder liver steatosis, and lower hepatic levels of triglycerides than mice that received a high-fat diet ad libitum (p &lt; 0.05). The numbers of Bacteroidetes and Firmicutes differed between mice that received a time-restricted high-fat diet and mice that received a high-fat diet ad libitum (p &lt; 0.05). Mice fed a time-restricted high-fat diet showed distinct circadian rhythms of hepatic expression of SIRT1, SREBP, and PPARα compared with mice fed a normal diet ad libitum, as well as the circadian rhythm of the abundance of Bacteroidetes and Firmicutes.Conclusions: Time-restricted feeding is associated with better metabolic conditions, perhaps owing to alterations in gut microbiota and the circadian pattern of molecules related to hepatic lipid metabolism, which were first to report.


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