Association analysis with lipid traits of 2 candidate genes (LRP12 and TRIB1) mapping to a SSC4 QTL for serum triglyceride concentration in pigs1

2013 ◽  
Vol 91 (4) ◽  
pp. 1531-1537 ◽  
Author(s):  
C. Melo ◽  
R. Quintanilla ◽  
D. Gallardo ◽  
A. Zidi ◽  
J. Jordana ◽  
...  
1976 ◽  
Vol 35 (2) ◽  
pp. 223-227 ◽  
Author(s):  
W. Marktl ◽  
Barbara Rudas

1. The results obtained for 236 Viennese schoolchildren between 11 and 12 years of age indicated that 38% of children had an increased concentration of cholesterol in their serum and 3% had an increased serum triglyceride concentration..2. The results of the preliminary study suggested that, by extending the dimensions of the screening, further problems, for example the correlation between different ‘risk’ factors and the significance of nutritional habits, might be studied.


2008 ◽  
Vol 233 (8) ◽  
pp. 1270-1277 ◽  
Author(s):  
Elissa K. Kluger ◽  
Richard Malik ◽  
William J. Ilkin ◽  
David Snow ◽  
David R. Sullivan ◽  
...  

2006 ◽  
Vol 91 (11) ◽  
pp. 4664-4668 ◽  
Author(s):  
Matti K. Karvonen ◽  
Soile Ruottinen ◽  
Markku Koulu ◽  
Ullamari Pesonen ◽  
Harri Niinikoski ◽  
...  

Abstract Context: The important role of neuropeptide Y (NPY) in the regulation of food intake and energy balance has been firmly documented in rodents, but human data are sparse. The recently identified functional Leu7Pro polymorphism in the signal peptide region of the prepro-NPY is a useful tool for the investigation of the role of NPY in men. Pro7 substitution has been associated with the following: plasma NPY concentration, the risk factors of cardiovascular disease, birth weight of children, serum triglyceride concentration, and the function of vascular endothelium. Objective: The objective of this study was to analyze the connection between Leu7Pro polymorphism and relative weight, nutrient intakes, and serum lipids in early childhood. We closely followed 647 healthy Finnish children participating in the Special Turku Risk Factor Intervention Project through their first 9 yr of life. Results: Leu7Pro polymorphism showed no relation to intakes of energy, macronutrients, or the relative weight in either gender. However, Pro7 substitution was associated with serum triglyceride concentration in boys at the ages of 5, 7, and 9 yr. Conclusion: The functional Leu7Pro polymorphism is not likely to be involved in the regulation of adiposity or major nutrient preferences in childhood. In boys, the Pro7 variant may have impact on serum triglyceride concentration.


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