Effects of porcine circovirus type 2 vaccine and increasing standardized ileal digestible lysine:metabolizable energy ratio on growth performance and carcass composition of growing and finishing pigs1

2012 ◽  
Vol 90 (1) ◽  
pp. 361-372 ◽  
Author(s):  
N. W. Shelton ◽  
M. D. Tokach ◽  
S. S. Dritz ◽  
R. D. Goodband ◽  
J. L. Nelssen ◽  
...  
Keyword(s):  
Growth Performance ◽  
Porcine Circovirus Type ◽  
Porcine Circovirus Type 2 ◽  
Carcass Composition ◽  
Energy Ratio ◽  
Porcine Circovirus

The effects of sire genotype and the porcine circovirus type 2 vaccine on the growth performance of pigs from weaning to slaughter

2009 ◽  
Vol 2009 ◽  
pp. 33-33
Author(s):  
A Taylor ◽  
S Jagger ◽  
P Toplis ◽  
I Wellock ◽  
H M Miller
Keyword(s):  
Growth Rate ◽  
Body Composition ◽  
Growth Performance ◽  
Meat Quality ◽  
Porcine Circovirus Type ◽  
Porcine Circovirus Type 2 ◽  
Porcine Circovirus ◽  
Lean Growth ◽  
Low Levels

Crossbreeding is common practice in commercial pig production as one way to increase lean growth and improve meat quality (Visscher et al., 2000). Reducing disease is another way to help improve growth rate in pigs. Porcine circovirus type 2 (PCV2) has devastated the pig industry in recent years. PCV2 infection increases mortality and reduces growth rate as it acts as an immunosuppressant thereby making pigs more susceptible to co-infections (Kixmöller et al 2008). Keeping disease at low levels has been achieved by improving husbandry standards, biosecurity, minimising presence of other pathogens and use of antibiotics. However vaccines against PVC2 are now available. The aim of this study was to investigate the effects of sire genotype and PCV2 vaccine on growth performance and body composition of pigs.

A field evaluation of mortality rate and growth performance in pigs vaccinated against porcine circovirus type 2

2008 ◽  
Vol 232 (6) ◽  
pp. 906-912 ◽  
Author(s):  
Kyle P. Horlen ◽  
Steve S. Dritz ◽  
Jerome C. Nietfeld ◽  
Steven C. Henry ◽  
Richard A. Hesse ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Growth Performance ◽  
Field Evaluation ◽  
Porcine Circovirus Type ◽  
Porcine Circovirus Type 2 ◽  
Porcine Circovirus

Immunoenhancement of Recombinant Neisseria meningitides PorB Protein on Porcine Circovirus Type 2 and Mycoplasma hyopneumoniae Genetically Engineered Vaccines

2019 ◽  
Vol 26 (10) ◽  
pp. 776-784
Author(s):  
Rui Yang ◽  
Yu Tao ◽  
Gaojian Li ◽  
Jian Chen ◽  
Jianhong Shu ◽  
...  
Keyword(s):  
Recombinant Protein ◽  
Mycoplasma Hyopneumoniae ◽  
Porcine Circovirus Type ◽  
Porcine Circovirus Type 2 ◽  
Genetically Engineered ◽  
Porcine Circovirus ◽  
Practical Applications ◽  
Neisseria Meningitides ◽  
Short Period

Background:Porcine circovirus and Mycoplasma hyopneumoniae can cause respiratory diseases in pigs, which cause serious economic loss in the worldwide pig industry. Currently, these infections are mainly prevented and controlled by vaccination. The new vaccines on the market are mainly composed of subunits and inactivated vaccines but usually have lower antigenicity than traditional live vaccines. Thus, there is an increasing need to develop new adjuvants that can cause rapid and long-lasting immunity to enhance the antigenic efficacy for vaccines. Studies have shown that meningococcal porin PorB can act as a ligand to combine with Toll-like receptors to activate the production of immunological projections and act as a vaccine immunological adjuvant.Objective:In this article, we expressed and purified the recombinant PorB protein and verified its immunogenicity against porcine circovirus type 2 and Mycoplasma hyopneumoniae genetically engineered vaccine.Methods:In this article, we used prokaryotic expression to express and purify recombinant PorB protein, four different concentrations of PorB protein, Freund's adjuvant with two genetically engineered vaccines were combined with subcutaneous immunization of mice.Results:Our study shows that the appropriate dose of the recombinant protein PorB can enhance the levels of humoral and cellular responses induced by two genetically engineered vaccines in a short period of time in mice. The PorB adjuvant group may cause statistically higher antibody titers for both genetically engineered vaccines compared to Freund's commercial adjuvant (P<0.001).Conclusion:The recombinant protein PorB may be a good candidate adjuvant for improving the protective effect of vaccines against porcine circovirus type 2 and Mycoplasma hyopneumoniae, and the protein can be used for future practical applications.

scholarly journals A Comparison of Virulence of Three Porcine Circovirus Type 2 (PCV2) Genotypes (a, b, and d) in Pigs Singularly Inoculated with PCV2 and Dually Inoculated with PCV2 and Porcine Reproductive and Respiratory Syndrome Virus

Pathogens ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 891
Author(s):  
Jeongmin Suh ◽  
Taehwan Oh ◽  
Keehwan Park ◽  
Siyeon Yang ◽  
Hyejean Cho ◽  
...  
Keyword(s):  
Porcine Circovirus Type ◽  
Porcine Circovirus Type 2 ◽  
Daily Weight Gain ◽  
Porcine Circovirus ◽  
Respiratory Syndrome Virus ◽  
Average Daily Weight Gain ◽  
Significant Difference ◽  
Lesion Severity ◽  
Severe Lung

The aim of this study was to compare the virulence of porcine circovirus type 2 (PCV2) genotypes in dually inoculated pigs with both three genotypes (a, b, and d) of PCV2 and porcine reproductive and respiratory syndrome virus-2 (PRRSV-2) versus pigs singularly inoculated with the same three PCV2 genotypes (a, b, and d). Differences in this comparison were found in PCV2 viremia levels, lung and lymphoid lesion severity, and the amount of PCV2 antigen within the lymphoid lesions. Regardless of PCV2 genotypes, pigs that were dually inoculated with PCV2/PRRSV had significantly higher clinical scores, less average daily weight gain, higher levels of PCV2 viremia, and more severe lug and lymphoid lesions compared to pigs singularly inoculated with PCV2. Among the dually infected pig groups, pigs infected with PCV2d/PRRSV-2 had significantly higher levels of PCV2 viremia, more severe lung and lymphoid lesions, and more PCV2-positive cells within lymphoid lesions compared to pigs dually inoculated with PCV2a/PRRSV-2 and PCV2b/PRRSV-2. The results of this study demonstrated significant differences in the virulence among dual inoculation of PCV2a/PRRSV-2, PCV2b/PRRSV-2, and PCV2d/PRRSV-2. A significant difference in the virulence among PCV2a, PCV2b, and PCV2d single-inoculated pig groups was not found with respect to the levels of PCV2 viremia and production of PCV2-associated lymphoid lesions.

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