0458 Effect of energy substrate and days on feed on plasma insulin response in finishing beef heifers

2016 ◽  
Vol 94 (suppl_5) ◽  
pp. 218-219
Author(s):  
F. Joy ◽  
K. M. Wood ◽  
G. B. Penner
Diabetes ◽  
1987 ◽  
Vol 36 (2) ◽  
pp. 179-186 ◽  
Author(s):  
R. A. Sicree ◽  
P. Z. Zimmet ◽  
H. O. King ◽  
J. S. Coventry

PEDIATRICS ◽  
1970 ◽  
Vol 45 (2) ◽  
pp. 236-245
Author(s):  
Robert M. Ehrlich ◽  
Sang Whay Kooh

Oral chlorpropamide was administered to 17 children with diabetes insipidus (D.I.). The cause of the D.I. was idiopathic, six; histiocytosis, five; craniopharyngioma, three; pinealoma, two, and post-traumatic, one. Twenty-four-hour urine volume and measurements of serum and urine osmolality at the beginning and end of a 7-hour water deprivation test were used to evaluatechlorpropamide therapy. Administration of 150 to 400 mg of chlorpropamide per day by mouth caused a reduction in urine volume in all patients (range 8 to 67%). No change in aldosterone, 17-hydroxycorticoids, or electrolyte excretion was noted. Serum electrolytes and glomerular filtration rate were not affected by therapy. Glucose tolerance and plasma insulin response remained normal in those patients tested. Mild leucine sensitivity without significant change in plasma insulin was induced in four children. During water deprivation, seven patients with secondary D.I. but only one with idiopathic D.I. produced hypertonic urine. Hypoglycemia developed in seven children and is the major hazard of treatment. Long-term management of D.I. has been possible in nine children. Oral chlorpropamide is a useful drug in children with vasopressin-sensitive diabetes insipidus.


2013 ◽  
Vol 9 (3-4) ◽  
pp. 209-217 ◽  
Author(s):  
S. Ringmark ◽  
A. Jansson

This study assessed the insulin response to forage intake with varying crude protein (CP) content in horses at rest and after exercise. Six geldings were fed three grass haylage-only diets for 7 days according to a 3×3 Latin square design. On day 7, blood samples were collected before and for 120 min after feeding 15% of the daily allowance before exercise (feeding A) and after standardised exercise (feeding B). Feed samples were collected before each feeding. Dry matter (DM) and nutrient content varied (DM: 37-58%, water-soluble carbohydrates minus fructans (WSC-f): 3-12% of DM, CP: 10-15% of DM) which resulted in a variation in nutrient intake within haylage batches. Based on individual CP and WSC-f intakes, intake groups were therefore formed (low and high CP intake; ≤ and ≯180 g CP/100 kg body weight, respectively and low and high WSC-f intake; ≤ and ≯100 g/100 kg body weight, respectively). Amino acids were analysed and intakes were generally higher in the high CP group than in the low CP group. An ANOVA model including horse, CP group and WSC-f intake explained 95% of the variation in plasma insulin response compared to 87% using a model including horse and WSC-f group alone. The plasma insulin area under curve (AUC) following feeding A tended to be higher in the high CP group than in the low CP group (P=0.08), but there was no difference after feeding B. Plasma glucose AUC was not affected by CP group (P≯0.05). The study indicates that the post-prandial plasma insulin response in horses fed a forage-only diet is increased by high WSC-f intake but may also be increased by high CP intake, at least at rest. However, due to the low number of observations further studies are needed.


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