scholarly journals Fine-needle aspiration cytology – A novel diagnostic technique in pemphigus

2021 ◽  
Vol 0 ◽  
pp. 1-3
Author(s):  
Beena Narayanan ◽  
O. T. Dhanya ◽  
N. Asokan

The term pemphigus is collectively used to describe a group of immunobullous disorders characterized by intraepidermal cleft and circulating antibodies against intercellular adhesion molecules. Pemphigus vegetans was first described as a variant of pemphigus vulgaris by Neumann in 1876. We report a case of 36-year-old female who presented with swelling of scalp, which was diagnosed as pemphigus by fine-needle aspiration cytology.

1989 ◽  
Vol 75 (3) ◽  
pp. 280-283 ◽  
Author(s):  
Stefano Ciatto ◽  
Silvia Cecchini ◽  
Anna Iossa ◽  
Grazia Grazzini ◽  
Dusca Bartoli

The authors report on 315 histologically confirmed consecutive breast cancer (BC) cases undergoing fine needle aspiration cytology (FNAC). Inadequate smears were infrequent (7%), particularly when reaspiration of inadequate cases was employed (1–2%). FNAC suspected BC in 81% of the total or 88% of adequate smears. Univariate and multivariate (Cox's model) analyses showed no correlation between inadequacy or suspect/positive FNAC rate and patient age, T category or histologic type. Differences in the inadequacy and suspect/positive rate were recorded among 30 operators (surgeons, oncologists, radiologists) performing the sampling, but the average results were consistent with literature reports. FNAC was found to be a useful diagnostic tool for BC diagnosis, and proper training of the highest number of operators is recommended to allow the widest diffusion of this diagnostic technique.


Med Phoenix ◽  
2018 ◽  
Vol 3 (1) ◽  
pp. 36-40
Author(s):  
Sushama Bhatta ◽  
Samir Singh ◽  
Sangita Regmi Chalise

Background: Cervical lymphadenopathy is one of the most frequent clinical manifestations of patients attending outpatient department. The etiology of cervical lymphadenopathy varies from inflammatory condition to malignant lesion. Fine needle aspiration cytology (FNAC) is a safe, easy and quick diagnostic technique. It has become the first line of investigation in the evaluation of lymphadenopathy. The objective of this study was to evaluate the spectrum of lesions in cervical lymphadenopathy and role of FNAC in the diagnosis of cervical lymphadenopathy.Methods: This study was conducted over a period of two years (May 2015 to May 2017). 206 patients with cervical lymphadenopathy were included in the study.Results: Most of the cases were non-neoplastic (91.74 %) whereas (8.26 %) cases were neoplastic. The most common cause of non-neoplastic lymphadenopathy was reactive lymphadenitis. Histocytological correlation was done in 32 cases. The diagnostic accuracy of FNAC for metastatic carcinoma and reactive lymphadenitis was 100% and 93.75% respectively.Conclusions: FNAC is a safe, cost effective and reliable procedure to diagnose the causes of cervical lymphadenopathy.Med Phoenix. Vol. 3, Issue. 1, 2018, Page: 36-40


1992 ◽  
Vol 106 (8) ◽  
pp. 755-757 ◽  
Author(s):  
N. W. Derias ◽  
W. H. Chong ◽  
A. F. Fitzgerald O'Connor

AbstractA 12-year-old boy presented with a three-month history of a painful parotid swelling. Fine needle aspiration cytology indicated a pleomorphic adenoma—an uncommon lesion in a child. This diagnostic technique plays a useful role in the investigation of head and neck swellings.


2014 ◽  
Vol 19 (2) ◽  
pp. 110-118
Author(s):  
Mohammad Amzad Hossain ◽  
Md Zahedul Alam ◽  
Md Rojibul Haque ◽  
Md Nazmul Haque ◽  
KM Nurul Alam ◽  
...  

Objective: To evaluate the role of Fine Needle Aspiration Cytology in the preoperative diagnosis of malignancy in parotid and submandibular gland neoplasm. Methods: This cross sectional study on 50 cases was conducted in the Department of Otolaryngology and Head-Neck Surgery of Sir Salimullah Medical College Mitford Hospital and Dhaka Medical College Hospital from January’2009 to June 2010. Results: Fine needle aspiration cytology findings of our all 50 cases were compared with postoperative histopathological reports. Out of the 50 cases, in 36(72%) cases of benign neoplasm and 7(14%) cases of malignant neoplasm, pre-operative FNAC findings and post operative histopathological findings were same. In 7 cases, FNAC and post operative histopathological findings did not matched. These were 2 (4%) false positive and 5 (10%) false negative result.In our study sensitivity of FNAC for reporting malignancy was 58.33%, specificity to rule out malignancy was 94.73% and overall accuracy in detecting malignant tumour was 86%. Positive predictive value and negative value were 77.77% and 87.80% respectively. It can be concluded that fine needle aspiration cytology is a safe, cheap and useful preoperative diagnostic tool in the diagnosis of malignancy in parotid and submandibular gland, but as fine needle aspiration cytology partly depends on operator skill, it may give false negative and false positive result. Conclusion: FNAC is a useful preoperative diagnostic tool for malignant parotid and submandibular glands with high specificity and sensitivity. DOI: http://dx.doi.org/10.3329/bjo.v19i2.17634 Bangladesh J Otorhinolaryngol 2013; 19(2): 110-118


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