Subsurface Cuttings Injection: Technical Challenges and Opportunities

2014 ◽  
Author(s):  
A. Maliardi ◽  
F. Cecconi ◽  
D. Simeone ◽  
S. Gumarov ◽  
T. Shokanov ◽  
...  
Keyword(s):  
Challenges And Opportunities ◽  
Technical Challenges

Subsurface Cuttings Injection: Technical Challenges and Opportunities

2014 ◽  
Author(s):  
A. Maliardi and F. Cecconi ◽  
D. Simeone ◽  
S. Gumarov ◽  
T. Shokanov ◽  
V. Anokhin ◽  
...  
Keyword(s):  
Challenges And Opportunities ◽  
Technical Challenges

scholarly journals Challenges and Opportunities for Small Molecule Aptamer Development

2012 ◽  
Vol 2012 ◽  
pp. 1-20 ◽  
Author(s):  
Maureen McKeague ◽  
Maria C. DeRosa
Keyword(s):  
Molecular Recognition ◽  
Small Molecules ◽  
Small Molecule ◽  
Chemical Biology ◽  
Biological Functions ◽  
High Affinity ◽  
Challenges And Opportunities ◽  
Recognition Elements ◽  
Technical Challenges ◽  
Viable Approach

Aptamers are single-stranded oligonucleotides that bind to targets with high affinity and selectivity. Their use as molecular recognition elements has emerged as a viable approach for biosensing, diagnostics, and therapeutics. Despite this potential, relatively few aptamers exist that bind to small molecules. Small molecules are important targets for investigation due to their diverse biological functions as well as their clinical and commercial uses. Novel, effective molecular recognition probes for these compounds are therefore of great interest. This paper will highlight the technical challenges of aptamer development for small molecule targets, as well as the opportunities that exist for their application in biosensing and chemical biology.

Sign in / Sign up

Export Citation Format

Share Document