Field Case Histories Demonstrating Critical Role of PLT Flow Model Selection for Improved Water Shut-off Results in Offshore Thailand

Project selection for first-year design courses can be complicated by the limited skill level of students in their first semester of an engineering program and the scalability required for multiple sections and large classes. Additionally, the project must address the course's learning objectives and provide a sense of authenticity to help students understand the role of engineers in society. Afirst-year design course can be seen by students as the ‘introduction to engineering,’ enabling them to decide whether to pursue engineering as a profession or not. In addition to the already taxing demands imposed on a project for a first-year design course, students at the University of Prince Edward Island completed a design project encompassing two engineering courses andcontributed to a scientific research study on bat conservation. Partnering with researchers in the Atlantic Veterinary College, students designed, built, and installed bat houses equipped with sensors to remotely collect temperature, humidity, and the presence of individual bats within the colony. Constructing 21 bat houses promoted conservation efforts of bats across the province and taught students the critical role of engineers in a sustainable society. This paper presents a discussion on project selection for first-year design courses, how the learning objectiveswere met for two first-year design courses during a pandemic, and describe the community partner's role\ throughout the design project.

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Flow Model Selection For Production Logging Interpretation

10.2118/145579-ms ◽

2011 ◽

Author(s):

Kittiphong Jongkittinarukorn ◽

Robert Peter Kerr

Keyword(s):

Model Selection ◽

Flow Model ◽

Selection For

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Role of Biomarkers in the Development of PARP Inhibitors

Biomarkers in Cancer ◽

10.4137/bic.s36679 ◽

2016 ◽

Vol 8s1 ◽

pp. BIC.S36679 ◽

Cited By ~ 9

Author(s):

Bratati Ganguly ◽

Sonia C. Dolfi ◽

Lorna Rodriguez-Rodriguez ◽

Shridar Ganesan ◽

Kim M. Hirshfield

Keyword(s):

Dna Repair ◽

Critical Role ◽

Parp Inhibitors ◽

Resistance Mechanisms ◽

Parp Inhibition ◽

Technological Advances ◽

Damage Repair ◽

Selection For ◽

Defective Dna Repair

Defects in DNA repair lead to genomic instability and play a critical role in cancer development. Understanding the process by which DNA damage repair is altered or bypassed in cancer may identify novel therapeutic targets and lead to improved patient outcomes. Poly(adenosine diphosphateribose) polymerase 1 (PARP1) has an important role in DNA repair, and novel therapeutics targeting PARP1 have been developed to treat cancers with defective DNA repair pathways. Despite treatment successes with PARP inhibitors (PARPi), intrinsic and acquired resistances have been observed. Preclinical studies and clinical trials in cancer suggest that combination therapy using PARPi and platinating agents is more effective than monotherapy in circumventing drug resistance mechanisms. Additionally, identification of biomarkers in response to PARPi will lead to improved patient selection for targeted cancer treatment. Recent technological advances have provided the necessary tools to examine many potential avenues to develop such biomarkers. This review examines the mechanistic rationale of PARP inhibition and potential biomarkers in their development for personalized therapy.

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The Role of the SLP in Autism Spectrum Disorder Screening and Assessment

Perspectives on Language Learning and Education ◽

10.1044/lle15.2.50 ◽

2008 ◽

Vol 15 (2) ◽

pp. 50-59 ◽

Cited By ~ 1

Author(s):

Amy Philofsky

Keyword(s):

Language Development ◽

Critical Role ◽

Children With Autism ◽

Autism Spectrum ◽

Children With Asd ◽

Prevalence Estimates ◽

Notable Increase ◽

Screening Assessment ◽

Critical Components

AbstractRecent prevalence estimates for autism have been alarming as a function of the notable increase. Speech-language pathologists play a critical role in screening, assessment and intervention for children with autism. This article reviews signs that may be indicative of autism at different stages of language development, and discusses the importance of several psychometric properties—sensitivity and specificity—in utilizing screening measures for children with autism. Critical components of assessment for children with autism are reviewed. This article concludes with examples of intervention targets for children with ASD at various levels of language development.

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