scholarly journals Prevalence of depression in patients with Diabetes Mellitus Type 2 (DM) and Chronic Obstructive Pulmonary Disease (COPD)

2013 ◽  
Author(s):  
Vineet Jalota ◽  
Sathyanarayana MT ◽  
Dhanashree Akshatha ◽  
Swarna Buddha Nayok
Keyword(s):  
Diabetes Mellitus ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Diabetes Mellitus Type 2 ◽  
Diabetes Mellitus Type ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Type 2 Dm ◽  
Prevalence Of Depression

Introduction: Depression has been bi-directionally associated with chronic medical disorders such as Diabetes Mellitus type 2(DM) and Chronic Obstructive Pulmonary Disease(COPD). Presence of depression complicates the treatment outcomes due to poor adherence to treatment regimens and is also associated with significant functional impairment ranging from impaired productivity to absenteeism. Aims: To estimate the prevalence of depression in patients with DM and COPD, and correlate them with socio-demographic variables. Settings and Design: A cross sectional hospital-based study was conducted on 30 patients having DM and 30 patients having COPD from January 2018 to June 2018. Methods and Material: Socio-demographic data was collected using semi-structured proforma and depression was assessed using Hamilton Depression Rating Scale (HAM-D). Statistical analysis used: Quantitative data is expressed in numbers and percentages. Pearson’s Chi-square was applied to compare the sociodemographic correlates amongst themselves with diagnosis of DM and COPD. Results: Prevalence of depression in patients with DM was 63.33% and in those with COPD was 66.67%. Socio-demographically, only living status was significant with DM (p= 0.069). Overall, most (56.41%) had mild levels of severity. Conclusions: In about two-thirds of patients having DM or COPD, psychiatric co-morbidity in the form of depression is present. Hospital admission due to acute exacerbation may lead to increase in depressive features. This may contribute to poor compliance to treatment of these medical illnesses subsequently. Thus, special measures for early detection and treatment of depression in patients with these medical co-morbidities should be implemented to enhance treatment outcome.

scholarly journals Diabetes mellitus type 2 in hospitalized patients with chronic obstructive pulmonary disease

2015 ◽  
Author(s):  
Evgeni Mekov ◽  
Yanina Slavova ◽  
Marianka Genova ◽  
Adelina Tsakova ◽  
Dimitar Kostadinov ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Chronic Obstructive Pulmonary Disease ◽  
Hospital Stay ◽  
Pulmonary Disease ◽  
Smoking Status ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Bulgarian Population

Diabetes mellitus (DM) affects 2-37% of patients with chronic obstructive pulmonary disease (COPD), with results being highly variable between studies. DM may also correlate with disease characteristics.The aim of this study was to examine the prevalence of DM and its correlation with comorbidities and COPD characteristics in patients with COPD admitted for exacerbation. 152 patients were studied for presence of DM. All of them were also assessed for vitamin D status and metabolic syndrome (MS). Data were gathered for smoking status and exacerbations during the last year. All patients completed CAT (COPD assessment test) and mMRC (Modified Medical Research Council Dyspnea scale) questionnaires and underwent spirometry. Duration of current hospital stay was recorded. 13.2% (20/152) of patients are taking medications for DM. Additional 21.7% (33/152) have newly discovered DM and 30.9% (47/152) have prediabetes. Only 34.2% of the studied patients do not have DM or prediabetes. 37% (40/108) of males have DM vs. 29,5% (13/44) of females (p=0.379). The prevalence of DM in this study is significantly higher when compared to an unselected Bulgarian population (12,8% in subjects over 45 years). 91% of patients with newly discovered diabetes had glycated hemoglobin (HbA1c)≥6,5% suggesting prolonged hyperglycemia. There is a correlation between the presence of DM and MS (p=0.008). The presence of DM is associated with more severe exacerbations (hospitalizations) during the previous year (p=0.003) and a longer hospital stay (p=0.006). DM is not associated with reduced quality of life and worse pulmonary function. The patients with COPD admitted for exacerbation are at great risk for impaired glucose metabolism which is associated with worse COPD characteristics. The majority of the patients in this study are unaware of having DM.

Surfactant protein D in chronic obstructive pulmonary disease and type 2 diabetes mellitus

2017 ◽  
Vol 30 (1) ◽  
pp. 297
Author(s):  
MaiA.H. Abou Elenin ◽  
NaglaaM Ghanayem ◽  
ElsayedS Abou Elnour ◽  
RababA El Wahsh ◽  
RaniaM.A. El-Shazlya
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Chronic Obstructive Pulmonary Disease ◽  
Type 2 Diabetes Mellitus ◽  
Pulmonary Disease ◽  
Surfactant Protein ◽  
Surfactant Protein D ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease

scholarly journals Cytokine status of patients with chronic obstructive pulmonary disease and type 2 diabetes mellitus

2017 ◽  
Vol 98 (2) ◽  
pp. 222-226
Author(s):  
S A Nedomolkina ◽  
O V Velikaya ◽  
V I Zoloedov
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Chronic Obstructive Pulmonary Disease ◽  
Type 2 Diabetes Mellitus ◽  
Pulmonary Disease ◽  
Inflammatory Cytokines ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Pro Inflammatory Cytokines

The review article is devoted to an actual problem of modern medicine - combined pathology of chronic obstructive pulmonary disease and type 2 diabetes mellitus. These 2 diseases take the first place in the structure of people’s mortality. The rate of chronic obstructive pulmonary disease and type 2 diabetes mellitus increases annually along with life length and according to different data reaches 35.8%. In the article scientists’ modern perception and known facts from scientific literature are presented. Special attention is given to cytokine status in chronic obstructive pulmonary disease and type 2 diabetes mellitus. Cytokines classification based on mechanism of action and their role in pathogenesis is presented. Systemic inflammation characteristic for both diseases presents as the increase of pro-inflammatory cytokines level in the blood and decrease of anti-inflammatory cytokines. Determining cytokines in patients with chronic obstructive pulmonary disease and type 2 diabetes mellitus has prognostic value. Mutual negative influence of these two diseases is directly associated with the increase of pro-inflammatory cytokines which are considered the reason for insulin resistance and type 2 diabetes mellitus. Despite the attempts to study cytokine status in patients with chronic obstructive pulmonary disease and type 2 diabetes mellitus the issues of treatment of combined pathology, diagnostic concentration of pro-inflammatory and anti-inflammatory cytokines, their role in pathogenesis and clinical presentation are still an open question. Certainly it is necessary to continue studying the cytokine status in patients with chronic obstructive pulmonary disease and type 2 diabetes mellitus to answer those questions.

Disorders of carbohydrate metabolism in chronic obstructive pulmonary disease

2016 ◽  
Vol 94 (6) ◽  
pp. 405-410
Author(s):  
Vyacheslav I. Kobylyansky
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Chronic Obstructive Pulmonary Disease ◽  
Type 2 Diabetes Mellitus ◽  
Pulmonary Disease ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
The Relationship

The literature data and our own experience suggest that chronic obstructive pulmonary disease can be an important risk factor of type 2 diabetes mellitus. The relationship between these two condition is virtually unexplored and pathogenteic mechanisms behind it remain unclear. There are reasons to attribute an important role to insulin resistance as one of the leading mechanisms. It is in the focus of the present work.

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