scholarly journals Effect of GSR Biofeedback Relaxation Training on Blood Glucose and Anxiety Level of Type 2 Diabetic Patients

2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Mahendra Kumar ◽  
Dr. Deepak Pandey ◽  
Dr. Priyamvada Shrivastva

The objective of this study was to determine the effect of GSR (galvanic skin resistance) biofeedback relaxation technique on blood glucose and anxiety level of type 2 diabetes patients. The total sample size for this study was 12 diabetes patients include 6 male and 6 female participants. Incidental sampling method was adopted to select the sample. Intervention program for the study was 20 days for each patient. The blood glucose and anxiety level were measured before and after the training on day 1st and 20th. Result indicates that there is significant mean difference between the score of blood glucose in pre and post conditions of the interventions. The blood sugar level of type 2 diabetes patients is lowered in post condition indicating the influence of biofeedback intervention. A sample of adequate size may reveal a significant effect of biofeedback. There is significant mean difference between the score of state – trait anxiety among pre and post test score of type 2 diabetes patients.

Electronics ◽  
2021 ◽  
Vol 10 (15) ◽  
pp. 1820
Author(s):  
Je-Hoon Lee ◽  
Jai-Chang Park ◽  
Seong-Beom Kim

Exercise enables continuous glycemic control for diabetic patients, and it is effective in preventing diabetic complications and maintaining emotional stability. However, it is difficult for diabetic patients to know the appropriate intensity and duration of exercise. Excessive exercise causes sudden hypoglycemia, and patients avoid therapeutic exercise or perform it conservatively owing to the repeated hypoglycemia symptoms. In this paper, we propose a new therapeutic exercise platform that supports type 2 diabetes patients to exercise regularly according to the exercise prescription received from the hospital. The proposed platform includes the following three significant contributions. First, we develop a hardware platform that automatically tracks and records all aerobic exercise performed by a patient indoors or outdoors using a wearable band and aerobic exercise equipment. Second, we devise a patient-specific exercise stress test to know whether the patient is exercising according to his or her usual exercise regimen. Finally, we develop a mobile application that informs patients in real-time whether they are exercising appropriately for their exercise regimen each time they exercise. For platform evaluation and future improvement, we received satisfaction ratings and functional improvements through a questionnaire survey on 10 type 2 diabetes patients and 10 persons without a diabetes diagnosis who had used the proposed platform for more than 3 months. Most users were (1) satisfied with automatic exercise recording, and (2) exercise time increased. Diabetics reported that their fasting blood glucose was dropped, and they were more motivated to exercise. These results prove that exercise must be combined with medication for blood glucose management in chronic diabetic patients. The proposed platform can be helpful for patients to continue their daily exercise according to their exercise prescription.


2022 ◽  
Vol 28 (1) ◽  
pp. 59-61
Author(s):  
Bin Zhang

ABSTRACT Introduction: Type 2 diabetes mellitus (T2DM), also known as non-insulin-dependent diabetes mellitus (NIDDM), accounts for more than 90% of the total number of diabetes mellitus cases and often occurs in middle-aged and elderly people. Objective: To investigate the effect of exercise intervention on insulin resistance in obese type 2 diabetes patients. Methods: Eighty-six obese diabetic patients were screened as experimental subjects in physical examinations and randomly divided into observation and control groups. Visceral fat volume, fasting blood glucose, and fasting insulin of all subjects were measured before and after completion of the 6-month experimental implementation. The insulin resistance was calculated for both groups and the values for each indicator were compared statistically between groups. Results: Control of body weight, body mass index, blood glucose, blood lipids and insulin resistance index were better in the observation group than in the control group, and the difference was statistically significant (P < 0.05). Conclusions: Basal intervention with quantitative exercise can significantly improve insulin resistance in obese type 2 diabetes patients and the effect is better than treatment with diet and conventional exercise. Level of evidence II; Therapeutic studies - investigation of treatment results.


2018 ◽  
Vol 31 (1) ◽  
pp. 1-12
Author(s):  
Elainy Peixoto Mariano STUDART ◽  
Soraia Pinheiro Machado ARRUDA ◽  
Helena Alves de Carvalho SAMPAIO ◽  
Tatiana Uchôa PASSOS ◽  
Antonio Augusto Ferreira CARIOCA

ABSTRACT Objective To identify the main dietary patterns in type 2 diabetes patients and study their association with glycemic indexes. Methods This is a cross-sectional study carried out in a diabetes treatment reference institution located in the city of Fortaleza (CE). Two R24h were applied, as well as 12h fast blood glucose tests and anthropometric assessments in 188 diabetic patients. The principal components factor analysis method was applied together with a Varimax orthogonal rotation method to identify dietary patterns. The Poisson Regression and the Spearman coefficient were used to test the association with glycemic indexes. Results A hundred eighty eight diabetic patients were evaluated, of which 51.1% patients had decompensated glucose values. Five main dietary patterns were identified: traditional Brazilian, energy-dense, infusion and wholegrain cereal, sandwich and dairy, and healthy diets, which explained 37.2% of the total variance in intake. A negative correlation with glucose was found for the traditional Brazilian diet (p=0.018; r=-0.173). Conclusion Out of the five identified dietary patterns consumed by the type 2 diabetes patients studied, a higher adherence to the traditional Brazilian dietary patterns resulted in lower blood glucose levels.


2016 ◽  
Vol 7 (6) ◽  
pp. 6-10
Author(s):  
Pinaki Saha ◽  
Sayantan Dasgupta ◽  
Sukla Nath ◽  
Pradipta Ghosh ◽  
Santanu Sen ◽  
...  

Background: Diabetes mellitus is a major health problem not only in India but worldwide. Our country presently is undergoing an epidemic stage of this non-communicable disease.Though several etiological background of type 2 diabetes has been well explained, yet a number of recent literatures suggested a potential role H2S producing enzymes in the etiology and management of this metabolic disorder.Aims and Objectives: Our aim was to elucidate the relationship of H2S synthesizing activity in plasma and fasting blood glucose in type 2 diabetic patients. Materials and Methods: Sixty-two newly diagnosed type 2 diabetes patients and equal number of non-diabetic controls were included in the study. Enzymatic activity of synthesizing H2S in plasma was estimated following methods described earlier with further modification and standardization in our laboratory. All other parameters were estimated by using standardized kits.Results:  FBG, PPBG, HbA1C, Fasting Insulin,  H2S synthesizing activity in plasma in patients are significantly higher (p< 0.05) than the corresponding values in healthy controls H2S synthesizing activity in plasma is positively correlated with fasting plasma glucose and the correlations is significant(p=0.05).Conclusion: Our study though a pilot study with a small sample size, has elucidated that the values of H2S synthesizing activity in plasma are significantly elevated in type 2 diabetic patients and this may help researchers to develop H2S modifying agents and enzyme inhibitors which may open up new horizon in the treatment modalities of type 2 diabetes mellitus.Asian Journal of Medical Sciences Vol.7(6) 2016 6-10


2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. A470-A470
Author(s):  
Tzvetelina Totomirova ◽  
Mila Arnaudova

Abstract Glycated haemoglobin (HbA1c) is used for defining of glucose control in diabetic patients nevertheless its insufficiency to present overall control in some specific cases. Continuous Glucose Monitoring (CGM) is usually used for adjustment of insulin doses but the derived data are helpful for exact glucose control. We assess the potency of HbAc for defining of real glucose control in subgroup of type 2 diabetes patients treated with different insulin regimens. We studied 54 diabetic patients (33 men, 21 women; age 60.23±5.99 years, disease duration 12.64±5.02 years) - 33 with type 2 diabetes on pre-mixed insulin, 21 with type 2 on multiple insulin injection (MII). Patients performed multiple daily blood glucose measurements of fasting and prandial blood glucose for three months period. HbA1c was measured and CGM by using iProTM for seven days was performed at the end of this period. In pre-mixed insulin treated group and in intensified regimen group, moderate positive correlation was found between HbA1c and mean blood glucose derived from CGM (7.64±1.40% and 7.69±1.23%, respectively 7.64±1.48mmol/l and 7.60±1.30mmol/l), with r1=0.642 (p&lt;0.01) and r2=0.570 (p&lt;0.05). Even lower was correlation between HbA1c and time-in-range (r1=0.431 and r2 =0.401). There were no correlations between HbA1c and percentage of time spent below the target and number of hypoglycemic episodes in each group. Same trend of correlations was found comparing HbA1c and mean BG level in eight-point profile. Based on HbA1c assessment 36.36% of patients on premixed insulin, 19.05% of type 2 patients on MII were with good control. After estimation of results from SMBG these percentage were respectively 28.14% and 12.11%. CGM defined 27.27% of patients on premixed insulin, 13.80% of type 2 patients on MII as well controlled. We conclude that in insulin treated type 2 patients HbA1c gives relative information about overall control with no precise presenting of glucose fluctuations and out-of-range values of blood glucose with no information about hypoglycemic episodes. Nevertheless, short observed period CGM data could give much information that is comparable to three months blood glucose measurement and could replace the use of HbA1c for assessment of overall control. Reference: (1) Chehregosha H, et al. Diabetes Ther. 2019; 10, 853–863 (2) Beyond A1c Writing Group. Diab Care. 2018; 41: e92-e94 (3) Hirsch I et al. Diabetes Tech Ther 2017, 19 (3): S38-S48


2019 ◽  
Vol 6 (3) ◽  
pp. 786
Author(s):  
Eda Dayakar ◽  
C. Sathya Sree ◽  
E. Sanjay

Background: Diabetes mellitus is a common health problem globally. Dyslipidaemia is a major risk factor to develop cardiovascular disease in diabetics. They present study was undertaken to find out the prevalence of dyslipidaemia in type 2 diabetic patients.Methods: The present study was a cross sectional study consisting of 46 (23 male and 23 female) known type 2 diabetes mellitus patients. Age, gender, duration of diabetes, body mass index (BMI) was recorder in all the diabetic patients.  Fasting blood glucose levels, total cholesterol, triglycerides, HDL, LDL, VLDL levels were measured using standard methods and recorded.Results: The average total cholesterol, triglycerides, LDL, HDL and VLDL were 200±42mg/dl, 169.62±89.79mg/dl, 132.45±36.38mg/dl,39.1±16.6mg/dl and 35.85±17.09mg/dl respectively. The incidence of occurrence of hypercholesterolemia was 58.6% and hypertriglyceridemia 36.9%. Increased levels of LDL were observed in 30 (65.2%) patients and reduced HDL was observed in 43 (93.4%) patients. The incidence rate of dyslipidaemia was higher in female diabetic patients when compared to male diabetic patients.Conclusions: Awareness on the dyslipidaemia and its risk factors should be provided to the type 2 diabetic patients as they are more prone to get cardiovascular disease and lipid profile also should be monitored regularly along with blood glucose levels.


2021 ◽  
Author(s):  
Zhiyang Wang ◽  
Carine Ronsmans ◽  
Benjamin Woolf

Background: Although previous studies suggested the protective effect of zinc for type-2 diabetes, the unitary causal effect remains inconclusive. Objective: We investigated the causal effect of zinc as a single intervention on glycemic control in type-2 diabetes patients, using a systematic review of RCTs and two-sample Mendelian randomization (MR). Methods: Four outcomes were identified: fasting blood glucose/fasting glucose, hemoglobin A1c (HbA1c), homeostasis model assessment of insulin resistance (HOMA-IR), and serum insulin/fasting insulin level. In the systematic review, four databases were searched up to June 2021. Results were synthesized through the random-effects meta-analysis. Single nucleotide polymorphisms (SNPs) that are independent and are strongly related to zinc supplements were selected from MR-base to perform the two-sample MR with inverse-variance weighted (IVW) coefficient. Results: In the systematic review, 14 trials were included. The zinc supplement led to a significant reduction in the post-trial mean of fasting blood glucose (mean difference (MD): -26.52, 95%CI: -35.13, -17.91), HbA1C (MD: -0.52, 95%CI: -0.90, -0.13), and HOMA-IR (MD: -1.65, 95%CI: -2.62, -0.68), compared to the control group. In the two-sample MR, zinc supplement with 2 SNPs associated with lower fasting glucose (IVW coefficient: -2.04, 95%CI: -3.26, -0.83), but not specified type-2 diabetes. Conclusion: Although the study was limited by the few trials (review) and SNPs (two-sample MR), we demonstrated that the single zinc supplementary improved glycemic control among type-2 diabetes patients with causal evidence to a certain extent.


2021 ◽  
pp. 13
Author(s):  
Subandrate ◽  
Raafqi Ranasasmita

Background: Increasing blood sugar level may increase free radical compounds in type 2 diabetes. Free radical compounds can cause oxidative stress, thereby decreasing endogenous antioxidants such as reduced glutathione (GSH). Objective: This study aimed to determine whether random blood glucose levels affect GSH in type 2 diabetes patients within the Malay race. Methods: This study was observational with case-control, involving 25 patients with uncomplicated type 2 diabetes (receiving metformin and/or glimipiride) and 25 healthy controls. Random blood glucose levels were determined using ACCU-CHECK® Kit. Blood GSH levels were determined by Sigma GSH Assay Kit. Results: Results show that type 2 diabetes patients have a significantly lower random blood glucose level compared with those of age-matched normal subjects (p<0.0001). Type 2 diabetic patients had significantly lower levels of GSH (p=0.00) than those of age-matched normal subjects. We found a moderate negative correlation (r=-0.437 and p=0.02) between the level of random blood glucose and the level of GSH. Conclusion: The depletion of GSH during hyperglycemia may neutralize the free radicals indirectly generated by the abundant of glucose.  


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