scholarly journals Effects of Group-Based Exercise on Range of Motion, Muscle Strength, Functional Ability, and Pain During the Acute Phase After Total Knee Arthroplasty: A Controlled Clinical Trial

2016 ◽  
Vol 46 (9) ◽  
pp. 742-748 ◽  
Author(s):  
Yoshinori Hiyama ◽  
Tsukasa Kamitani ◽  
Osamu Wada ◽  
Kiyonori Mizuno ◽  
Minoru Yamada
Keyword(s):  
Clinical Trial ◽  
Total Knee Arthroplasty ◽  
Muscle Strength ◽  
Range Of Motion ◽  
Acute Phase ◽  
Knee Arthroplasty ◽  
Functional Ability ◽  
Controlled Clinical Trial ◽  
Total Knee

scholarly journals Preemptive Analgesia in Total Knee Arthroplasty: Comparing the Effects of Single Dose Combining Celecoxib with Pregabalin and Repetition Dose Combining Celecoxib with Pregabalin: Double-Blind Controlled Clinical Trial

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Andri M. T. Lubis ◽  
Rangga B. V. Rawung ◽  
Aida R. Tantri
Keyword(s):  
Clinical Trial ◽  
Total Knee Arthroplasty ◽  
Knee Arthroplasty ◽  
Preemptive Analgesia ◽  
Controlled Clinical Trial ◽  
Double Blind ◽  
Significant Difference ◽  
Total Knee ◽  
Group 2 ◽  
Group 1

Acute pain is the most common early complication after total knee arthroplasty causing delayed mobilization and increased demands of morphine, leading to higher operative cost. Several studies have assessed the effectiveness, side-effects, and ease of use of various analgesics. Preemptive analgesia with combined celecoxib and pregabalin has been reported to yield positive outcomes. In this randomized, double-blind controlled clinical trial, 30 subjects underwent surgery for total knee arthroplasty using 15-20mg bupivacaine 5% epidural anesthesia. All subjects were divided into three groups. Group 1 was given celecoxib 400mg and pregabalin 150mg 1 hour before the operation, Group 2 was given celecoxib 200mg and pregabalin 75mg twice daily starting from 3 days before the operation, and Group 3 was given a placebo. The outcome was measured with Visual Analog Scale, knee range of motion, and postoperative mobilization. There was a significant difference in postoperative morphine usage between the groups that were administered with preemptive analgesia and the placebo group, but no significant difference was found between Group 1 and Group 2 that were given preemptive analgesia at different doses. ROM and postoperative mobilization were not significantly different among the three groups. Two patients in the first group, one patient in the second group, and one patient in the third group developed nausea. Preemptive analgesia is proven to reduce postoperative usage of morphine independent of the dosage. We recommend the use of combined celecoxib and pregabalin as preemptive analgesia after the total knee arthroplasty procedure. This trial is registered with NCT03523832 (ClinicalTrials.gov).

scholarly journals Importance of knee flexion range of motion during the acute phase after total knee arthroplasty

2020 ◽  
Vol 23 (2) ◽  
pp. 143-148
Author(s):  
Tomohiro OKA ◽  
Osamu WADA ◽  
Tsuyoshi ASAI ◽  
Hideto MARUNO ◽  
Kiyonori MIZUNO
Keyword(s):  
Total Knee Arthroplasty ◽  
Range Of Motion ◽  
Acute Phase ◽  
Knee Arthroplasty ◽  
Knee Flexion ◽  
Total Knee

Intraoperative Music Reduces Perceived Pain After Total Knee Arthroplasty –A Blinded, Prospective, Randomized, Placebo-Controlled Clinical Trial

2008 ◽  
Vol 21 (04) ◽  
pp. 275-278 ◽  
Author(s):  
Xavier Simcock ◽  
Richard Yoon ◽  
Peter Chalmers ◽  
Jeffrey Geller ◽  
Howard Kiernan ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Total Knee Arthroplasty ◽  
Knee Arthroplasty ◽  
Controlled Clinical Trial ◽  
Perceived Pain ◽  
Total Knee
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