A Simple Method of Matric Structural Analysis: Part III - Analysis of Flexible Frames and Stiffened Cylindrical Shells

1958 ◽  
Vol 25 (6) ◽  
pp. 385-394 ◽  
Author(s):  
BERTRAM KLEIN
Keyword(s):  
Structural Analysis ◽  
Cylindrical Shells ◽  
Simple Method ◽  
Stiffened Cylindrical Shells

Comparative Study Concerning the Methods of Calculation of the Critical Axial Buckling Load for Stiffened Cylindrical Shells

2018 ◽  
Vol 69 (8) ◽  
pp. 2000-2004 ◽  
Author(s):  
Maria Zaharia ◽  
Alexandru Pupazescu ◽  
Cristian Mihai Petre
Keyword(s):  
Numerical Analysis ◽  
Structural Analysis ◽  
Axial Compression ◽  
Cylindrical Shells ◽  
Buckling Load ◽  
Critical Buckling Load ◽  
The Real ◽  
Axial Buckling ◽  
Real Geometry ◽  
Stiffened Cylindrical Shells

As demonstrated in numerous theoretical and experimental studies [1], the buckling behaviour of stiffened cylindrical shells (SCS) is strongly influenced by the presence of geometric imperfections caused by the manufacturing process and/or exploitation. Therefore, the design norms recommend the use of reduction coefficients with very low values, resulting in a significant reduction of the maximum load applied. In order to calculate the critical buckling load as accurately as possible it is necessary to know the real geometry of SCS. In case of SCS, the structural analysis based on the use of the finite element method (FEM), using models that reflect the real geometry of the shell determined from measurements, lead to a better evaluation of the critical buckling load. The structural analysis with FEM is accepted more and more by standards, EN 1993-1-6:2007 [2] specifying the types of numerical analysis accepted for cylindrical shells. The aim of this study is to compare the results concerning the critical buckling load for SCS under axial compression, obtained with both the analytical and FEM methods for real geometries obtained from measurements. For this purpose, scale models of SCS were used, for which were determined, by measuring, the values of the deviations from the median radius at several points on the shells surface. These deviations were then incorporated in the numerical analysis with FEM and it was determined, for each cylindrical shell, the value of the critical axial buckling load, by using geometrically nonlinear analysis. In order to validate the results of the numerical analysis, the analysed SCS were subjected to axial compression within an experimental program and the experimental data were compared with the results established on the basis of analytical and numerical calculation.

scholarly journals Structural analysis of human dual-specificity phosphatase 22 complexed with a phosphotyrosine-like substrate

2015 ◽  
Vol 71 (2) ◽  
pp. 199-205 ◽  
Author(s):  
George T. Lountos ◽  
Scott Cherry ◽  
Joseph E. Tropea ◽  
David S. Waugh
Keyword(s):  
Crystal Structure ◽  
Structural Analysis ◽  
Phosphatase Activity ◽  
Small Molecule ◽  
Molecular Basis ◽  
Protein Tyrosine Phosphatases ◽  
Simple Method ◽  
Dual Specificity Phosphatase ◽  
Dual Specificity ◽  
Nitrophenyl Phosphate

4-Nitrophenyl phosphate (p-nitrophenyl phosphate, pNPP) is widely used as a small molecule phosphotyrosine-like substrate in activity assays for protein tyrosine phosphatases. It is a colorless substrate that upon hydrolysis is converted to a yellow 4-nitrophenolate ion that can be monitored by absorbance at 405 nm. Therefore, the pNPP assay has been widely adopted as a quick and simple method to assess phosphatase activity and is also commonly used in assays to screen for inhibitors. Here, the first crystal structure is presented of a dual-specificity phosphatase, human dual-specificity phosphatase 22 (DUSP22), in complex with pNPP. The structure illuminates the molecular basis for substrate binding and may also facilitate the structure-assisted development of DUSP22 inhibitors.

Imperfection-sensitivity of eccentrically stiffened cylindrical shells.

AIAA Journal ◽  
1967 ◽  
Vol 5 (3) ◽  
pp. 392-401 ◽  
Author(s):  
JOHN W. HUTCHINSON ◽  
JOHN C. AMAZIGO
Keyword(s):  
Cylindrical Shells ◽  
Imperfection Sensitivity ◽  
Stiffened Cylindrical Shells

Optimization of ring stiffened cylindrical shells

AIAA Journal ◽  
1975 ◽  
Vol 13 (10) ◽  
pp. 1319-1325 ◽  
Author(s):  
Allen J. Bronowicki ◽  
Richard B. Nelson ◽  
Lewis P. Felton ◽  
Lucien A. Schmit
Keyword(s):  
Cylindrical Shells ◽  
Stiffened Cylindrical Shells
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