New technologies for cryogenic propellant management for next generation launchers

Author(s):  
Benjamin LEGRAND ◽  
Jerome LACAPERE ◽  
Sebastien BIANCHI
2012 ◽  
pp. 311-337
Author(s):  
Dimitris E. Charilas ◽  
Athanasios D. Panagopoulos ◽  
Philip Constantinou

This chapter addresses the critical issue of Quality of Service (QoS) provisioning in next generation wireless networks. While the QoS offered to users may be enhanced through innovative protocols and new technologies, future trends should take into account the efficiency of the resource allocation strategies and the network/terminal cooperation as well. 4G networks will be characterized by an heterogeneous environment where several access networks will be available. The purpose of this chapter is to summarize techniques that enable efficient distribution of resources exploiting the existing infrastructure. Such techniques may involve either smart selection mechanisms or cooperating schemes among network entities. Since decision-making processes are examined, the use of game theory is considered as a valuable asset in the authors’ work. To this end, the chapter also collects applications of both non-cooperative and cooperative game theory applications in wireless networks. The main aspects of both game types are presented and several games are modeled.


Author(s):  
Paul Fergus

The number of consumer devices that are being equipped with networking capabilities is increasing rapidly. This is seen as a fundamental strategy within the consumer electronics domain where failure to provide such support may result in a considerable loss in market share. As end users become more comfortable with the idea of networking the devices they own, there will be a need to allow the heterogeneous devices they own to seamlessly work together irrespective of their capabilities or conventional usage scenarios. Addressing this challenge means that next generation mobile multimedia will be highly multidisciplinary where advances from many research domains will be included. In parallel, users will be empowered where they will not only be able to generate user content, but also interact with it. Content itself will become increasingly more influenced by the environment, where new technologies, such as sensor networks, will play a significant part. Social networks and immersive environments are commonplace, where users now choose to socialise within these environments. Many mobile multimedia solutions will capitalise on the benefits social networking technologies provide to help change the face of next generation mobile multimedia, where real-time interaction with content at anytime and anyplace will become standard. In this chapter we provide a discussion on the state-of-the-art research initiatives that are trying to address these challenges. A discussion is presented on some of the more recent background work and a view of what future mobile multimedia might look like. Throughout the discussion we present the challenges faced by many research communities and the likely trends that will emerge given such challenges.


2017 ◽  
Vol 41 (S1) ◽  
pp. S23-S23
Author(s):  
M. Faurholt-Jepsen

Bipolar Disorder is a common and complex mental disorder with a prevalence of 1-2% and accounts as one of the most important causes of disability at age 15-44 years worldwide.Electronic versions of self-monitoring tools and symptom registration using computers, personal digital assistants (PDAs), text messages, and web interfaces have been described in the literature and a large number of commercial Smartphone applications for patients with bipolar disorder are available.The Next Generation Mobile Platforms for Health, in Mental Disorders project (the NYMPHA-MD project), funded by the European Union's Seventh Framework program for research, technological development and demonstration, focuses on the implementation of a Pre-Commercial Procurement of mobile e-health service for supporting physicians and patients in the treatment of bipolar disorder through continuous patients monitoring in order to dynamically support illness management and potentially identify early warning signs.The NYMPHA-MD project will define the framework of a Pre-Commercial Procurement for the provisioning of next generation services advocated for mental health treatment with a special focus on bipolar disorder based on the use of new technologies, open standards and open platforms.The NYMPHA-MD project will focus on identifying requirements involved in the structuring of mental health services with a focus on bipolar disorder treatment including medical, technological, patients, legal, ethical, policy, risk management and business-orientation needs in order to construct a reference model of service provisioning useful in different European contexts.Disclosure of interestThe author has not supplied his declaration of competing interest.


Author(s):  
Randall Aadland ◽  
Fred Wilson ◽  
Ryan Schwab ◽  
Mike Patterson ◽  
George Soulas ◽  
...  

Author(s):  
S. Aoki ◽  
Y. Tsukuda ◽  
E. Akita ◽  
Y. Iwasaki ◽  
R. Tomat ◽  
...  

The 701G1 50Hz Combustion Turbine continues a long line of large heavy-duty single-shaft combustion turbines by combining the proven efficient and reliable concepts of the 501F and 701F. The output of the 701G1 is 255MW with combined cycle net efficiency of over 57%. A pan of component development was conducted under the joint development program with Tohoku Electric Power Co., Inc. and a part of the design work was carried out under the cooperation with Westinghouse Electric Corporation in the U.S.A. and Fiat Avio in Italy. This gas turbine is going to be installed to “Higashi Niigata Power Plants NO.4” of Tohoku Electric Power Co., Inc. in Japan. This plant will begin commercial operation in 1999. This paper describes some design results and new technologies in designing and developing this next generation 1500°C class advanced gas turbine.


2018 ◽  
Vol 61 (3) ◽  
pp. 98-102 ◽  
Author(s):  
Ivana Kašubová ◽  
Veronika Holubeková ◽  
Katarína Janíková ◽  
Barbora Váňová ◽  
Zuzana Sňahničanová ◽  
...  

The development of the new technologies such as the next-generation sequencing (NGS) makes more accessible the diagnosis of genetically heterogeneous diseases such as Lynch syndrome (LS). LS is one of the most common hereditary form of colorectal cancer. This autosomal dominant inherited disorder is caused by deleterious germline mutations in one of the mismatch repair (MMR) genes – MLH1, MSH2, MSH6 or PMS2, or the deletion in the EPCAM gene. These mutations eventually result in microsatellite instability (MSI), which can be easily tested in tumor tissue. According to the actual recommendations, all patients with CRC that are suspect to have LS, should be offered the MSI testing. When the MSI is positive, these patients should be recommended to genetic counseling. Here we report a pilot study about the application of NGS in the LS diagnosis in patients considered to have sporadic colorectal cancer. The inclusion criteria for the NGS testing were MSI positivity, BRAF V600E and MHL1 methylation negativity. We have used 5 gene amplicon based massive parallel sequencing on MiSeq platform. In one patient, we have identified a new pathogenic mutation in the exon 4 of the MSH6 gene that was previously not described in ClinVar, Human Gene Mutation Database, Ensembl and InSight databases. This mutation was confirmed by the Sanger method. We have shown that the implementation of new criteria for colorectal patients screening are important in clinical praxis and the NGS gene panel testing is suitable for routine laboratory settings.


Author(s):  
Daniel Rittschof ◽  
Christina Chai ◽  
Serena Lay Ming Teo ◽  
James S. Maki

The last 50 years of fouling research and management taught us that indiscriminate use of toxic approaches damages ecosystem services of estuaries and oceans critical to man’s existence. Next generation environmentally benign management requires knowledge of the fouling process and an understanding of the consequences of different management options. An intermediate step may be additives that fit with existing business models and distribution systems, but that carry a much reduced environmental footprint. Subsequently, the evolution of a next generation hull fouling management system with limited toxicity easy clean surfaces should replace or augment the existing commercial easy-release coatings. These new technologies require new business models and infrastructure. The path for a new commercial hull coating, from a concept to the actual product takes 25 to 35 years to complete. Major challenges include fitting in with existing business models and systems and meeting regulations. Leveraging on our experience in the development of additives as a case example, we offer a perspective on what the new fouling management systems might involve and discuss issues to be addressed as limited toxicity easy-clean coatings gain market share. As existing business cannot easily adapt to a different business model, evolution of new management solutions will require resources, a necessary long term perspective, and close working relationships between business and science to enable products in the global market. 


2014 ◽  
Vol 42 (1) ◽  
pp. 19-27 ◽  
Author(s):  
Pascal Borry ◽  
Mahsa Shabani ◽  
Heidi Carmen Howard

In the last few decades, great progress has been made in both genetic and genomic research. The development of the Human Genome Project has increased our knowledge of the genetic basis of diseases and has given a tremendous momentum to the development of new technologies that make widespread genetic testing possible and has increased the availability of previously inaccessible genetic information. Two examples of this exponential evolution are the increasing implementation of next-generation sequencing technologies in the clinical context and the expanding commercial offer of genetic tests directly-to-consumers.Firstly, the rapid development of next generation sequencing technologies (i.e., high-throughput and massively parallel DNA sequencing technologies) has substantially reduced both the cost and the time required to sequence an entire human genome. These technologies are increasingly being used in the clinical setting with the goal of diagnosing conditions of presumed genetic origin that cannot be explained by targeted sequencing approaches.


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