Influence Of Microgravity On Left Ventricular Sphericity: A Finite Element Model Of The Heart

2012 ◽  
Author(s):  
Richard Summers ◽  
Weston Smith ◽  
Ryan Gilbrech ◽  
Jun Liao ◽  
Benjamin Weed ◽  
...  
Keyword(s):  
Finite Element ◽  
Finite Element Model ◽  
Element Model ◽  
Left Ventricular

Mechanism underlying mechanical dysfunction in the border zone of left ventricular aneurysm: a finite element model study

2001 ◽  
Vol 71 (2) ◽  
pp. 654-662 ◽  
Author(s):  
Julius M Guccione ◽  
Scott M Moonly ◽  
Pavlos Moustakidis ◽  
Kevin D Costa ◽  
Michael J Moulton ◽  
...  
Keyword(s):  
Finite Element ◽  
Finite Element Model ◽  
Element Model ◽  
Left Ventricular ◽  
Border Zone ◽  
Left Ventricular Aneurysm ◽  
Ventricular Aneurysm ◽  
Model Study

scholarly journals Organ-level validation of a cross-bridge cycling descriptor in a left ventricular finite element model: effects of ventricular loading on myocardial strains

2017 ◽  
Vol 5 (21) ◽  
pp. e13392 ◽  
Author(s):  
Sheikh Mohammad Shavik ◽  
Samuel T. Wall ◽  
Joakim Sundnes ◽  
Daniel Burkhoff ◽  
Lik Chuan Lee
Keyword(s):  
Finite Element ◽  
Finite Element Model ◽  
Element Model ◽  
Left Ventricular ◽  
Cross Bridge ◽  
Organ Level

scholarly journals The Effect of Trabeculae Carneae on Left Ventricular Diastolic Compliance: Improvement in Compliance With Trabecular Cutting

2017 ◽  
Vol 139 (3) ◽  
Author(s):  
David L. Halaney ◽  
Arnav Sanyal ◽  
Navid A. Nafissi ◽  
Daniel Escobedo ◽  
Martin Goros ◽  
...  
Keyword(s):  
Finite Element ◽  
Finite Element Model ◽  
Human Heart ◽  
Wall Stress ◽  
Element Model ◽  
Left Ventricular ◽  
Finite Element Simulations ◽  
Fem Simulations ◽  
Diastolic Compliance

The role of trabeculae carneae in modulating left ventricular (LV) diastolic compliance remains unclear. The objective of this study was to determine the contribution of trabeculae carneae to the LV diastolic compliance. LV pressure–volume compliance curves were measured in six human heart explants from patients with LV hypertrophy at baseline and following trabecular cutting. The effect of trabecular cutting was also analyzed with finite-element model (FEM) simulations. Our results demonstrated that LV compliance improved after trabecular cutting (p < 0.001). Finite-element simulations further demonstrated that stiffer trabeculae reduce LV compliance further, and that the presence of trabeculae reduced the wall stress in the apex. In conclusion, we demonstrate that integrity of the LV and trabeculae is important to maintain LV stiffness and loss in trabeculae leads to more LV compliance.

Impact of Weightlessness on Cardiac Shape and Left Ventricular Stress/Strain Distributions

2013 ◽  
Vol 135 (12) ◽  
Author(s):  
Ilana Iskovitz ◽  
Mohammad Kassemi ◽  
James D. Thomas
Keyword(s):  
Finite Element ◽  
Finite Element Model ◽  
Shape Change ◽  
Parabolic Flight ◽  
Element Model ◽  
Left Ventricular ◽  
Constitutive Relationship ◽  
Gravitational Fields ◽  
Numerical Predictions ◽  
The Impact

In this paper, a finite element model of the heart is developed to investigate the impact of different gravitational loadings of Earth, Mars, Moon, and microgravity on the cardiac shape and strain/stress distributions in the left ventricle. The finite element model is based on realistic 3D heart geometry, detailed fiber/sheet micro-architecture, and a validated orthotropic cardiac tissue model and constitutive relationship that capture the passive behavior of the heart at end-diastole. The model predicts the trend and magnitude of cardiac shape change at different gravitational levels with great fidelity in comparison to recent cardiac sphericity measurements performed during simulated reduced-gravity parabolic flight experiments. Moreover, the numerical predictions indicate that although the left ventricular strain distributions remain relatively unaltered across the gravitational fields and the strain extrema values occur at the same relative locations, their values change noticeably with decreasing gravity. As for the stress, however, both the magnitude and location of the extrema change with a decrease in the gravitational field. Consequently, tension regions of the heart on Earth can change into compression regions in space.

A Finite Element Model of Left Ventricular Cellular Transplantation in Dilated Cardiomyopathy

ASAIO Journal ◽  
2002 ◽  
Vol 48 (5) ◽  
pp. 508-513 ◽  
Author(s):  
Renée L. Quarterman ◽  
Scott Moonly ◽  
Arthur W. Wallace ◽  
Julius Guccione ◽  
Mark B. Ratcliffe
Keyword(s):  
Finite Element ◽  
Finite Element Model ◽  
Dilated Cardiomyopathy ◽  
Element Model ◽  
Left Ventricular ◽  
Cellular Transplantation

A FINITE ELEMENT MODEL OF LEFT VENTRICULAR CELLULAR TRANSPLANTATION IN DILATED CARDIOMYOPATHY

ASAIO Journal ◽  
2001 ◽  
Vol 47 (2) ◽  
pp. 120
Author(s):  
Renée L. Ouarterman ◽  
Scott Moonly ◽  
Julius Guccione ◽  
Mark Ratcliffe
Keyword(s):  
Finite Element ◽  
Finite Element Model ◽  
Dilated Cardiomyopathy ◽  
Element Model ◽  
Left Ventricular ◽  
Cellular Transplantation
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