Principal component analysis on 3D scanned compressor blades for probabilistic CFD simulation

Author(s):  
Alexander Lange ◽  
Matthias Voigt ◽  
Konrad Vogeler ◽  
Erik Johann
2021 ◽  
Vol 9 (10) ◽  
pp. 1069
Author(s):  
Stefan Harries ◽  
Sebastian Uharek

The paper shows the application of a flexible approach of partially-parametric modelling on the basis of radial basis functions (RBF) for the modification of an existing hull form (baseline). Different to other partially-parametric modelling approaches, RBF functions allow defining sources which lie on the baseline and targets which define the intended new shape. Sources and targets can be corresponding sets of points, curves and surfaces. They are used to derive a transformation field that subsequently modifies those parts of the geometry which shall be subjected to variation, making the approach intuitive and quick to set up. Since the RBF approach may potentially introduce quite a few degrees-of-freedom (DoF) a principal component analysis (PCA) is utilized to reduce the dimensionality of the design space. PCA allows the deliberate sacrifice of variability in order to define variations of interest with fewer variables, then being called principal parameters (prinPar). The aim of combining RBFs and PCA is to make simulation-driven design (SDD) easier and faster to use. Ideally, the turn-around time within which to achieve noticeable improvements should be 24 h, including the time needed to set up both the CAD model and the CFD simulation as well as to run a first optimisation campaign. An electric catamaran was chosen to illustrate the combined approach for a meaningful application case. Both a potential and a viscous solver were utilized, namely, SHIPFLOW XPAN (SHF) and Neptuno (NEP), respectively. Rather than to compare the two codes in any detail the purpose of this was to study the efficacy of the proposed approach of combining RBF and PCA for solvers of different fidelity. All investigations were realized within CAESES, a versatile process integration and design optimisation environment (CAESES). It is shown that meaningful reductions of total resistance and, hence, improvements of energy efficiency can be realized within very few simulation runs. If a one-stop steepest descent is applied as a deterministic search strategy, for instance, some 10 to 12 CFD runs are needed to already identify better hulls, rendering turn-around times of a day of work and a night of number crunching a realistic option.


Author(s):  
Spencer Bunnell ◽  
Steven Gorrell ◽  
John Salmon ◽  
Christopher Thelin ◽  
Christopher Ruoti

Abstract Design space exploration (DSE) is the process whereby a designer seeks to understand some results across a set of design variations. Structural DSE of turbomachinery compressor blades is often challenging because the large number of design variables make it difficult to learn the effect that each variable has upon the stress contours. Principal component analysis (PCA) of the stress contours is used as a way to understand how the stress contours change over the design space. Two methods are introduced to address the challenge of understanding how the stress changes over a large number of variables. First, a two-point correlation is applied to relate the design variables to the scores of each principal component. Second, a coupling of the stress and coordinate location of each node in PCA is developed which also indicates how the stress variations relate to geometric variations. These provide insight to how design variables influence the stress. It is shown how these methods use PCA as DSE tools to better explore the structural design space of compressor blades. Better DSE can improve compressor blades and the computational cost needed for their design.


VASA ◽  
2012 ◽  
Vol 41 (5) ◽  
pp. 333-342 ◽  
Author(s):  
Kirchberger ◽  
Finger ◽  
Müller-Bühl

Background: The Intermittent Claudication Questionnaire (ICQ) is a short questionnaire for the assessment of health-related quality of life (HRQOL) in patients with intermittent claudication (IC). The objective of this study was to translate the ICQ into German and to investigate the psychometric properties of the German ICQ version in patients with IC. Patients and methods: The original English version was translated using a forward-backward method. The resulting German version was reviewed by the author of the original version and an experienced clinician. Finally, it was tested for clarity with 5 German patients with IC. A sample of 81 patients were administered the German ICQ. The sample consisted of 58.0 % male patients with a median age of 71 years and a median IC duration of 36 months. Test of feasibility included completeness of questionnaires, completion time, and ratings of clarity, length and relevance. Reliability was assessed through a retest in 13 patients at 14 days, and analysis of Cronbach’s alpha for internal consistency. Construct validity was investigated using principal component analysis. Concurrent validity was assessed by correlating the ICQ scores with the Short Form 36 Health Survey (SF-36) as well as clinical measures. Results: The ICQ was completely filled in by 73 subjects (90.1 %) with an average completion time of 6.3 minutes. Cronbach’s alpha coefficient reached 0.75. Intra-class correlation for test-retest reliability was r = 0.88. Principal component analysis resulted in a 3 factor solution. The first factor explained 51.5 of the total variation and all items had loadings of at least 0.65 on it. The ICQ was significantly associated with the SF-36 and treadmill-walking distances whereas no association was found for resting ABPI. Conclusions: The German version of the ICQ demonstrated good feasibility, satisfactory reliability and good validity. Responsiveness should be investigated in further validation studies.


2020 ◽  
Vol 4 (11) ◽  
pp. 676-681
Author(s):  
V.V. Sapozhnikova ◽  
◽  
A.L. Bondarenko ◽  

Aim: to determine the association between clinical laboratory parameters, the production of cytokines (IL-17A, -23, -33, -35), and specific IgM and IgG in the serum of patients with Lyme borreliosis without erythema migrans. Patients and Methods: complete blood count, the concentrations of IL-17A, -23, -33, -35, and the levels of specific IgM and IgG were measured during acute infection and convalescence (n=30). The control group included age- and sex-matched healthy individuals (n=30). Statistical analysis was performed using the StatSoft Statistica v 10.0 software (parametric and non-parametric methods and multifactorial analysis, i.e., principal component analysis). Results: most (80%) patients with Lyme borreliosis without erythema migrans are the people of working age. In most patients, the combination of the specific antibodies against Borrelia afzelii and Borrelia garinii (76.7%) and severe intoxication and inflammatory process (100%) were detected. Moderate and severe disease associated with meningism was diagnosed in 90% and 10%, respectively. The mean duration of hectic period was 8.3±1.27 days. Abnormal ECG was reported in 40% of patients, i.e., conduction abnormalities in 20%, sinus bradycardia in 16.7%,and sinus tachycardia in 3.3%. The clinical laboratory signs of hepatitis without jaundice were identified in 26.7%. During treatment, the significant reduction in band and segmented neutrophil counts as well as the significant increase in platelet count were revealed compared to these parameters at admission. Abnormal cytokine levels (i.e., the increase in IL-17A, -23, -33 and the deficiency of IL-35) were detected. Conclusions: multifactorial analysis has demonstrated that the severity of immunological abnormalities in patients with Lyme borreliosis without erythema migrans is associated with fever, cardiac and liver disorders, the high levels of IL-23 and IL-33, and the lack of IL-35 and specific IgM and IgG. KEYWORDS: tick-borne borreliosis, Lyme disease without erythema migrans, clinical laboratory signs, cytokines, specific antibodies, multifactorial analysis, principal component analysis. FOR CITATION: Sapozhnikova V.V., Bondarenko A.L. Multifactorial analysis of clinical laboratory signs, the levels of IL-17A, IL-23, IL-33, IL-35, and specific antibodies in the serum of patients with Lyme borreliosis without erythema migrans. Russian Medical Inquiry. 2020;4(11):676–681. DOI: 10.32364/2587-6821-2020-4-11-676-681.


2018 ◽  
Vol 6 (7) ◽  
pp. 715-723 ◽  
Author(s):  
Stephany C. de Rezende ◽  
Jo鉶 A. Pinto ◽  
Isabel P. Fernandes ◽  
Fernanda V. Leimann and Maria-Filomena Barreiro

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