Modified State Observer for Orbit Uncertainty Estimation

2011 ◽  
Author(s):  
Nathan Harl ◽  
Karthikeyan Rajagopal ◽  
Sivasubramanya Balakrishnan
Keyword(s):  
State Observer ◽  
Uncertainty Estimation ◽  
Orbit Uncertainty

Neural Network Based Modified State Observer for Orbit Uncertainty Estimation

2013 ◽  
Vol 36 (4) ◽  
pp. 1194-1209 ◽  
Author(s):  
Nathan Harl ◽  
Karthikeyan Rajagopal ◽  
S. N. Balakrishnan
Keyword(s):  
Neural Network ◽  
State Observer ◽  
Uncertainty Estimation ◽  
Orbit Uncertainty

Development and Certification of Formononetin Reference Material for Quality Control of Functional Foods and Botanical Supplements

2019 ◽  
Vol 15 (5) ◽  
pp. 553-559
Author(s):  
Ningbo Gong ◽  
Baoxi Zhang ◽  
Kun Hu ◽  
Zhaolin Gao ◽  
Guanhua Du ◽  
...  
Keyword(s):  
Quality Control ◽  
Reference Material ◽  
Functional Foods ◽  
Certified Reference Materials ◽  
Coulometric Titration ◽  
Pharmaceutical Formulations ◽  
Uncertainty Estimation ◽  
Expanded Uncertainty ◽  
Scanning Calorimetry ◽  
Botanical Supplements

Background: Formononetin is a common soy isoflavonoid that can be found abundantly in many natural plants. Previous studies have shown that formononetin possesses a variety of activities which can be applied for various medicinal purposes. Certified Reference Materials (CRMs) play a fundamental role in the food, traditional medicine and dietary supplement fields, and can be used for method validation, uncertainty estimation, as well as quality control. Methods: The purity of formononetin was determined by Differential Scanning Calorimetry (DSC), Coulometric Titration (CT) and Mass Balance (MB) methods. Results: This paper reports the sample preparation methodology, homogeneity and stability studies, value assignment, and uncertainty estimation of a new certified reference material of formononetin. DSC, CT and MB methods proved to be sufficiently reliable and accurate for the certification purpose. The purity of the formononetin CRM was therefore found to be 99.40% ± 0.24 % (k = 2) based on the combined value assignments and the expanded uncertainty. Conclusion: This CRM will be a reliable standard for the validation of the analytical methods and for quality assurance/quality control of formononetin and formononetin-related traditional herbs, food products, dietary supplements and pharmaceutical formulations.

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