Enabling Modular Design Platforms using Variants in Model-Based Design

Author(s):  
Saurabh Mahapatra
Keyword(s):  
2019 ◽  
Vol 5 ◽  
Author(s):  
Albert Albers ◽  
Nikola Bursac ◽  
Helmut Scherer ◽  
Clemens Birk ◽  
Jonas Powelske ◽  
...  

Modular design allows to reduce costs based on scaling effects. However, due to strong alternating effects between the resulting modules and products, methods and tools are required that enable engineers to use specific views in which the respective information can be linked and retrieved according to the situation. Within the scope of this paper, the model-based systems engineering (MBSE) approach is used to model the complex real-world problem of vehicle modular kits. The aim is to investigate the potentials in this context, how modular kits and products can be efficiently modeled and finally how MBSE can support modular design. In order to investigate this in detail, two extensive studies are carried out in a company over a period of three years. The studies show that modular kits lead to an increased complexity of development. Across industries and companies, the demand for reference product models is shown, which facilitate the unification of inhomogeneous partial models and serve as a knowledge repository for the development of future product generations. On this basis, a framework is derived which enables the reuse of large proportions of the product models of previous product generations. This framework is evaluated on the basis of five case studies.


2020 ◽  
Vol 43 ◽  
Author(s):  
Peter Dayan

Abstract Bayesian decision theory provides a simple formal elucidation of some of the ways that representation and representational abstraction are involved with, and exploit, both prediction and its rather distant cousin, predictive coding. Both model-free and model-based methods are involved.


2001 ◽  
Vol 7 (S2) ◽  
pp. 578-579
Author(s):  
David W. Knowles ◽  
Sophie A. Lelièvre ◽  
Carlos Ortiz de Solόrzano ◽  
Stephen J. Lockett ◽  
Mina J. Bissell ◽  
...  

The extracellular matrix (ECM) plays a critical role in directing cell behaviour and morphogenesis by regulating gene expression and nuclear organization. Using non-malignant (S1) human mammary epithelial cells (HMECs), it was previously shown that ECM-induced morphogenesis is accompanied by the redistribution of nuclear mitotic apparatus (NuMA) protein from a diffuse pattern in proliferating cells, to a multi-focal pattern as HMECs growth arrested and completed morphogenesis . A process taking 10 to 14 days.To further investigate the link between NuMA distribution and the growth stage of HMECs, we have investigated the distribution of NuMA in non-malignant S1 cells and their malignant, T4, counter-part using a novel model-based image analysis technique. This technique, based on a multi-scale Gaussian blur analysis (Figure 1), quantifies the size of punctate features in an image. Cells were cultured in the presence and absence of a reconstituted basement membrane (rBM) and imaged in 3D using confocal microscopy, for fluorescently labeled monoclonal antibodies to NuMA (fαNuMA) and fluorescently labeled total DNA.


Author(s):  
Charles Bouveyron ◽  
Gilles Celeux ◽  
T. Brendan Murphy ◽  
Adrian E. Raftery

Author(s):  
Jonathan Jacky ◽  
Margus Veanes ◽  
Colin Campbell ◽  
Wolfram Schulte
Keyword(s):  

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