Numerical Simulations of Arterial and Venous Bleeding for Small Diameter Punctures

Author(s):  
Matthew McGarry ◽  
Darren Hitt ◽  
Timothy Harris
2018 ◽  
Vol 40 (9-10) ◽  
pp. 802-817 ◽  
Author(s):  
Paolo Toninelli ◽  
Stefano Bortolin ◽  
Marco Azzolin ◽  
Davide Del Col

Author(s):  
Ivaylo Nedyalkov ◽  
Ian Gagnon ◽  
Jesse Shull ◽  
John Brindley ◽  
Martin Wosnik

Wingtip devices are common in aeronautical applications and are increasingly used on wind turbines. However, their use in hydrokinetic energy conversion applications such as tidal turbines to date is minimal, due to the concern for increased bio-fouling and also the fact that there is little or no data publically available describing their cavitation characteristics. In this study, three wingtip designs were considered for hydrokinetic turbine applications: a plain foil with a rounded tip (considered the reference case), a generic wingtip device (a winglet), and a novel “split-tip” device. The tips were studied numerically and experimentally at different angles of attack. The numerical simulations were performed in OpenFOAM using the k-omega SST model to predict the lift and drag characteristics of a “base” foil with each of the three wingtip devices. Additionally the pressure and vorticity were observed. Experiments were conducted in the University of New Hampshire High-Speed Cavitation Tunnel – HiCaT. A modular experimental test bed with an elliptical foil section was developed specifically for the study. The test bed extends to the centerline of the tunnel where wingtips are attached, and has four small-diameter tube openings to accommodate pressure measurements and/or mass injection studies. Water tunnel data were obtained for lift, and cavitation inception, and compared to the numerical simulations. The numerical results show decreased vorticity with presence of the wingtip devices, however, the advantage of using wingtips for decreasing drag and increasing lift forces is not conclusively exhibited. The experimental measurements suggest that there is a significant suppression of tip vortex cavitation with the use of wingtip devices at high angles of attack (around 10 degrees), but the advantage of using the wingtip devices diminishes at lower angles of attack. It was shown by Arndt [1] that tip-vortex cavitation on hydrofoils can be related to the lift coefficient and the Reynolds number, where the cavitation index at inception is proportional to the square of the section lift coefficient and the Reynolds number based on hydrofoil chord, taken to the power m. The power exponent m has been generally accepted to be approximately 0.4. This relation is made into an equation via a coefficient of proportionality K, which depends on the wingtip and foil section geometry, and has been empirically determined to have values between 0.025 and 0.056 for previously investigated wings. While the value of the coefficient K for the reference wing tip remained comparatively constant for the range of conditions investigated (angles of attack, Reynolds numbers), it varied significantly for the foil terminated by the winglet. This may be due to the non-elliptical load distribution in the span-wise direction, but also raises the question whether the standard tip-vortex cavitation correlation for hydrofoils is applicable for general wingtip devices.


Author(s):  
C. C. O. Trigo ◽  
C. K. Morooka

Vertical pipes are extensively applied on offshore petroleum operations, such as subsea wellbore drilling, wellbore re-entry, installations of equipment on the sea bottom, hydrocarbon production as the conductor for oil and gas from the wellhead at the sea bottom, among other applications. Recent oil and gas field discoveries in ultra deepwater brought an increase of the amount of produced and processed petroleum onboard of floating production system. Consequently, the process plant demands more cooling capacity. One of the alternatives is to elevate cold sea water. The present study aims to improve the understanding of the behavior of a vertical pipe forced to move at its upper end in a water tank. Displacements along the pipe length are measured, and main features of the behavior of the pipe model with its bottom end free are observed. Motions imposed at the vertical pipe intent to represent motions of the surface from the floating platform or ship, due to waves, currents and wind. Pipe model vibrations are analyzed, and results allowed improvements for the input in numerical model simulations to Orcaflex software. Developments of the analysis procedure and evaluations of the experiment allow more reliable design of riser operations with its bottom end free in actual sea operations. In the present work, a physical model with a pipe of small diameter has been developed for the laboratory experiment, and an optical measurement system is used to measure the pipe model displacement in the water tank. Motions are imposed at the top termination by a mechanical device. Experiment is described in details and comparative analyses between experiment and numerical simulations were carried out. Results from numerical simulations as well as from the experiment brought important contributions for description and understanding of the vertical pipe behavior.


Author(s):  
T. G. Gregory

A nondestructive replica technique permitting complete inspection of bore surfaces having an inside diameter from 0.050 inch to 0.500 inch is described. Replicas are thermally formed on the outside surface of plastic tubing inflated in the bore of the sample being studied. This technique provides a new medium for inspection of bores that are too small or otherwise beyond the operating limits of conventional inspection methods.Bore replicas may be prepared by sliding a length of plastic tubing completely through the bore to be studied as shown in Figure 1. Polyvinyl chloride tubing suitable for this replica process is commercially available in sizes from 0.037- to 0.500-inch diameter. A tube size slightly smaller than the bore to be replicated should be used to facilitate insertion of the plastic replica blank into the bore.


Author(s):  
Asish C. Nag ◽  
Lee D. Peachey

Cat extraocular muscles consist of two regions: orbital, and global. The orbital region contains predominantly small diameter fibers, while the global region contains a variety of fibers of different diameters. The differences in ultrastructural features among these muscle fibers indicate that the extraocular muscles of cats contain at least five structurally distinguishable types of fibers.Superior rectus muscles were studied by light and electron microscopy, mapping the distribution of each fiber type with its distinctive features. A mixture of 4% paraformaldehyde and 4% glutaraldehyde was perfused through the carotid arteries of anesthetized adult cats and applied locally to exposed superior rectus muscles during the perfusion.


Author(s):  
J W Steeds ◽  
R Vincent

We review the analytical powers which will become more widely available as medium voltage (200-300kV) TEMs with facilities for CBED on a nanometre scale come onto the market. Of course, high performance cold field emission STEMs have now been in operation for about twenty years, but it is only in relatively few laboratories that special modification has permitted the performance of CBED experiments. Most notable amongst these pioneering projects is the work in Arizona by Cowley and Spence and, more recently, that in Cambridge by Rodenburg and McMullan.There are a large number of potential advantages of a high intensity, small diameter, focussed probe. We discuss first the advantages for probes larger than the projected unit cell of the crystal under investigation. In this situation we are able to perform CBED on local regions of good crystallinity. Zone axis patterns often contain information which is very sensitive to thickness changes as small as 5nm. In conventional CBED, with a lOnm source, it is very likely that the information will be degraded by thickness averaging within the illuminated area.


Author(s):  
S.F. Corcoran

Over the past decade secondary ion mass spectrometry (SIMS) has played an increasingly important role in the characterization of electronic materials and devices. The ability of SIMS to provide part per million detection sensitivity for most elements while maintaining excellent depth resolution has made this technique indispensable in the semiconductor industry. Today SIMS is used extensively in the characterization of dopant profiles, thin film analysis, and trace analysis in bulk materials. The SIMS technique also lends itself to 2-D and 3-D imaging via either the use of stigmatic ion optics or small diameter primary beams.By far the most common application of SIMS is the determination of the depth distribution of dopants (B, As, P) intentionally introduced into semiconductor materials via ion implantation or epitaxial growth. Such measurements are critical since the dopant concentration and depth distribution can seriously affect the performance of a semiconductor device. In a typical depth profile analysis, keV ion sputtering is used to remove successive layers the sample.


Author(s):  
Morten H. Nielsen ◽  
Lone Bastholm

During the last 5 years the diameter of the gold probes used for immuno-cytochemical staining at the electron microscopical (EM) level has been decreased. The advantage of small diameter gold probes is an overall increased labelling density. The disadvantage is a lower detectability due to the low electron density of smaller gold particles consequently an inconvenient high primary magnification needed for EM examination. Since 1 nm gold particles are barely visible by conventional EM examination the need for enlargement by silverenhancement of the gold particles has increased.In the present study of ultrathin cryosectioned material the results of immunostaining using 5 nm gold conjugated antibody and 1 nm gold conjugated antibodies are compared after silverenhancement of the 1 nm gold particles.Slices of freshly isolated mouse pituitary gland were immersion fixed for 20 min in 2 % glutaraldehyde /2 % paraformaldehyde. Blocks cryoprotected with 2.3 M sucrose were frozen in liquid nitrogen and ultra-cryosectioned on a RMC cryoultra-microtome.


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