Computational modeling of human leukocyte dynamics using a visco-elastic compound drop model

2001 ◽  
Author(s):  
Saikrishna Marella ◽  
H. Udaykumar
Keyword(s):  
Computational Modeling ◽  
Human Leukocyte ◽  
Elastic Compound

Abstract # OR-8: Serum 25-Hydroxyvitamin D Associates with Human Leukocyte Antigen (HLA) Polymorphisms

2016 ◽  
Vol 22 ◽  
pp. 6
Author(s):  
Leena Kinnunen ◽  
Valma Harjutsalo ◽  
Heljä-Marja Surcel ◽  
Christel Lamberg-Allardt ◽  
Jaakko Tuomilehto ◽  
...  
Keyword(s):  
Human Leukocyte Antigen ◽  
Human Leukocyte ◽  
Leukocyte Antigen ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D

Computational modeling of high pressure combustion mechanism in scram accelerator

2000 ◽  
Vol 10 (PR11) ◽  
pp. Pr11-131-Pr11-141 ◽  
Author(s):  
J.-Y. Choi ◽  
B.-J. Lee ◽  
I.-S. Jeung
Keyword(s):  
High Pressure ◽  
Computational Modeling ◽  
Combustion Mechanism

Gene Polymorphisms and Their Association to Coronavirus Family Infections: Susceptibility in Different Populations

2020 ◽  
Vol 5 ◽  
Keyword(s):  
Genetic Variants ◽  
Viral Infections ◽  
Human Leukocyte ◽  
Asian Population ◽  
African Region ◽  
Mediterranean Populations ◽  
Susceptibility To Infection ◽  
Asian Populations ◽  
Spread Pattern ◽  
Different Populations

Human leukocyte antigen (HLA) loci are highly polymorphic and determine differential features of the immune response in subjects from different regions. HLA genes have been proposed to determine genetic susceptibility to several diseases, particularly to viral infections. Moreover, it has been suggested that each ethnic group could have a different specificity of T-lymphocyte reactivity to the same viral infections. In this review, we analyzed the distribution of HLA types in countries of the Asian, European and North African region. Also, we studied the relation between these HLA polymorphisms and susceptibility to infection by the coronavirus. Our findings indicated that homozygosity would increase susceptibility to viral infections and, in some cases, to coronavirus infection. HLA types showing higher susceptibility were reported in Asian population, including China, Singapore, and Taiwan. In contrast, lower susceptibility HLA variants were detected among African populations, some Asian populations, and Mediterranean populations. The presented evidence along with the spread pattern of COVID-19 infection suggests that HLA genetic variants might be related to its infection susceptibility and severity. The investigation of HLA genetic variants distribution would be a useful tool to predict different populations’ susceptibility to viral infections.

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