scholarly journals Relationship of Potential Inflammatory Markers Namely Neutrophile Lymphocyte Ratio and Platelet Lymphocyte Ratio With the Severity of Obstructive Sleep Apnea

2017 ◽  
Vol 1 (3) ◽  
Author(s):  
Oğuz DİKBAŞ ◽  
Nilgün ERTEN ◽  
Fatma KÜÇÜKER ◽  
Özge YILMAZ AKŞEHİRLİ
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Inflammatory Markers ◽  
Lymphocyte Ratio ◽  
Platelet Lymphocyte Ratio ◽  
Obstructive Sleep ◽  
Relationship Of

Inverse Relationship of Subjective Daytime Sleepiness to Sympathetic Activity in Patients With Heart Failure and Obstructive Sleep Apnea

CHEST Journal ◽  
2012 ◽  
Vol 142 (5) ◽  
pp. 1222-1228 ◽  
Author(s):  
Luigi Taranto Montemurro ◽  
John S. Floras ◽  
Philip J. Millar ◽  
Takatoshi Kasai ◽  
Joseph M. Gabriel ◽  
...  
Keyword(s):  
Heart Failure ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Daytime Sleepiness ◽  
Sympathetic Activity ◽  
Inverse Relationship ◽  
Obstructive Sleep ◽  
Patients With Heart Failure ◽  
Relationship Of

Relationship of obstructive sleep apnea syndrome with the 5-HT2A receptor gene in Brazilian patients

2012 ◽  
Vol 17 (1) ◽  
pp. 57-62 ◽  
Author(s):  
Thiago Bittencourt Ottoni de Carvalho ◽  
Marcela Suman ◽  
Fernando Drimel Molina ◽  
Vânia Belintani Piatto ◽  
José Victor Maniglia
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
Receptor Gene ◽  
Sleep Apnea Syndrome ◽  
Obstructive Sleep ◽  
Apnea Syndrome ◽  
Relationship Of

Effectiveness of Intranasal Sodium Hyaluronate in Mitigating Adverse Effects of Nasal Continuous Positive Airway Pressure Therapy

2017 ◽  
Vol 31 (6) ◽  
pp. 364-369 ◽  
Author(s):  
Ignazio La Mantia ◽  
Claudio Andaloro
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Inflammatory Markers ◽  
Mucociliary Clearance ◽  
Saline Solution ◽  
Positive Airway Pressure ◽  
Sleep Apnea Syndrome ◽  
Sodium Hyaluronate ◽  
Obstructive Sleep ◽  
Nasal Mucociliary Clearance

Background Nasal continuous positive airway pressure (CPAP) in moderate-to-severe cases of obstructive sleep apnea can cause nasal discomfort and other undesirable problems. Objective The aim of our study was to test the effects of sodium hyaluronate on nasal problems that patients experienced in their daily lives, sleepiness, nasal resistance to airflow, nasal mucociliary clearance, changes in inflammatory markers, and compliance to CPAP in three groups of patients with obstructive sleep apnea syndrome on CPAP therapy. Methods A total of 102 patients with a confirmed diagnosis of obstructive sleep apnea syndrome (apnea-hypopnea index [AHI] of ≥10/hour) were randomized into three treatment groups: (1) hyaluronate plus CPAP, (2) saline solution plus CPAP, and (3) CPAP-only groups. Outcome measures were the extent of improvement in the Mini Rhinoconjunctivitis Quality of Life Questionnaire (MiniRQLQ) mean scores, sleepiness, nasal resistance to airflow, nasal mucociliary clearance, changes in inflammatory markers, and compliance to CPAP. Significant improvement in each outcome measure was determined by comparing scores at baseline and after 4 weeks for each treatment group. Results Significant improvement in the MiniRQLQ overall mean score was observed both in the hyaluronate plus CPAP (p <0.00001) and saline solution plus CPAP groups (p <0.01), although the hyaluronate plus CPAP group had better improvement compared with the saline solution plus CPAP group (0.24 versus 0.12, respectively). An increase in nasal inflammatory markers and saccharin transit test score was observed in all three groups, although it was statistically lower in the hyaluronate plus CPAP group (all p <0.001). Conclusion Intranasal hyaluronate showed significant benefits in patients who received CPAP therapy, but future studies over a longer period of time after treatment should be performed to corroborate our findings.

scholarly journals The Impact of Obstructive Sleep Apnea on Metabolic and Inflammatory Markers in Consecutive Patients with Metabolic Syndrome

PLoS ONE ◽  
2010 ◽  
Vol 5 (8) ◽  
pp. e12065 ◽  
Author(s):  
Luciano F. Drager ◽  
Heno F. Lopes ◽  
Cristiane Maki-Nunes ◽  
Ivani C. Trombetta ◽  
Edgar Toschi-Dias ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Inflammatory Markers ◽  
Obstructive Sleep ◽  
The Impact
Sign in / Sign up

Export Citation Format

Share Document