Periodontal Tissue Changes Caused by Orthodontic Intrusion Associated with Normal Gingiva, Experimental Periodontitis and Healthy Gingiva Treated Periodontitis

1993 ◽  
Vol 47 (6) ◽  
pp. 607-619
Author(s):  
Shu Morimoto
Keyword(s):  
Periodontal Tissue ◽  
Tissue Changes ◽  
Experimental Periodontitis

Melatonin prevents radiation-induced oxidative stress and periodontal tissue breakdown in irradiated rats with experimental periodontitis

2016 ◽  
Vol 52 (3) ◽  
pp. 438-446 ◽  
Author(s):  
O. Köse ◽  
T. Arabaci ◽  
A. Kizildag ◽  
B. Erdemci ◽  
D. Özkal Eminoğlu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Periodontal Tissue ◽  
Radiation Induced ◽  
Experimental Periodontitis

Involvement of Cot/Tp12 in Bone Loss during Periodontitis

2010 ◽  
Vol 89 (2) ◽  
pp. 192-197 ◽  
Author(s):  
T. Ohnishi ◽  
A. Okamoto ◽  
K. Kakimoto ◽  
K. Bandow ◽  
N. Chiba ◽  
...  
Keyword(s):  
Bone Loss ◽  
Alveolar Bone ◽  
Alveolar Bone Loss ◽  
Periodontal Tissue ◽  
Rankl Expression ◽  
Periodontal Tissues ◽  
Tnf Α ◽  
Experimental Periodontitis ◽  
Deficient Mice

Periodontitis causes resorption of alveolar bone, in which RANKL induces osteoclastogenesis. The binding of lipopolysaccharide to Toll-like receptors causes phosphorylation of Cot/Tp12 to activate the MAPK cascade. Previous in vitro studies showed that Cot/Tp12 was essential for the induction of RANKL expression by lipopolysaccharide. In this study, we examined whether Cot/Tp12 deficiency reduced the progression of alveolar bone loss and osteoclastogenesis during experimental periodontitis. We found that the extent of alveolar bone loss and osteoclastogenesis induced by ligature-induced periodontitis was decreased in Cot/Tp12-deficient mice. In addition, reduction of RANKL expression was observed in periodontal tissues of Cot/Tp12-deficient mice with experimental periodontitis. Furthermore, we found that Cot/Tp12 was involved in the induction of TNF-α mRNA expression in gingiva of mice with experimental periodontitis. Our observations suggested that Cot/Tp12 is essential for the progression of alveolar bone loss and osteoclastogenesis in periodontal tissue during experimental periodontitis mediated through increased RANKL expression.

An Experimental Study on Periodontal Tissue Changes Following Loss of Occlusal Contact

1978 ◽  
Vol 22 (4) ◽  
pp. 759-766
Author(s):  
Yuzo Takaki ◽  
Yasumasa Akagawa ◽  
Shigemitsu Hamada ◽  
Hiroshi Tamagawa ◽  
Takashi Sato ◽  
...  
Keyword(s):  
Experimental Study ◽  
Periodontal Tissue ◽  
Occlusal Contact ◽  
Tissue Changes

scholarly journals GSK3 inhibitor-loaded osteotropic Pluronic hydrogel effectively mitigates periodontal tissue damage associated with experimental periodontitis

Biomaterials ◽  
2020 ◽  
Vol 261 ◽  
pp. 120293
Author(s):  
Yosif Almoshari ◽  
Rongguo Ren ◽  
Haipeng Zhang ◽  
Zhenshan Jia ◽  
Xin Wei ◽  
...  
Keyword(s):  
Tissue Damage ◽  
Periodontal Tissue ◽  
Experimental Periodontitis ◽  
Gsk3 Inhibitor
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