scholarly journals Identification of Chemical Compounds from the Ethanolic Extract of the Bark of Bauhinia tomentosa L. By GC-MS Analysis

Author(s):  
Gopalakrishnan S. ◽  
Vadivel E.

The bark of Bauhinia tomentosa L. is used wildly used for the treatment of varies ailments such as inflammation, wound, dysentery, skin diseases and for microbial infections. In the present study the ethanolic extract of the bark of Bauhinia tomentosa L. has been subjected to Gas Chromatography-Mass Spectrometry (GC-MS) analysis, while the mass spectra of the compounds found in the extract was matched with the National Institute of Standards and Technology (NIST) library. GC-MS analysis revealed the presence of fourteen phytochemical constituents, These compounds were identified by comparing their retention time and peak area with that of literature and by interpretation of mass spectra. The major chemical constituents are 4-(Benzyloxy)-1-methoxy-2(3,7-dimethylocta-2,6-dienyl)-benzene (10.88%), Levodopa (6.39%) and (9E, 12E) - Methyl octadeca-9,12-dienoate (5.68%) which possess many biological activities. Hence these studies pave a platform to screen many bioactive components for wound healing.

Author(s):  
Mohamed Zaky Zayed ◽  
Benedict Samling

<p><strong>Objective: </strong>This study was conducted to identify the phytochemical constituents of <em>Leucaena leucocephala</em> leaf extracts using gas chromatography-mass spectrometry (GC-MS).</p><p><strong>Methods: </strong>Hexane, petroleum ether, chloroform, ethyl acetate and methanol leaves extract of <em>L. leucocephala</em> were analyzed using GC-MS, while the mass spectra of the compounds found in the extract were matched with the National Institute of Standards and Technology (NIST) library.</p><p><strong>Results: </strong>GC-MS analysis of <em>L. leucocephala</em> leaves revealed the presence of 30 compounds and the major chemical constituents were Squalene (41.02%), Phytol (33.80%), 3,7,11,15-Tetramethyl-2-hexadecen-1-ol (30.86%) and 3,7,11-Tridecatrienenitrile, 4,8,12-trimethyl (25.64%). Some of these compounds have been reported to possess various biological activities such as antioxidant, antimicrobial, hepatoprotective, antiparasitic, insecticide, nematicide, pesticide, anti coronary, antiarthritic, antiandrogenic, hypocholesterolemic, cancer preventive, anti-cancer, analgesic, anesthetic, allergenic and etc.</p><p><strong>Conclusion: </strong>The findings of this study indicating that<em> L.</em> <em>leucocephala</em> leaves possess various potent bioactive compounds and is recommended as a plant of phytopharmaceutical importance.</p>


Author(s):  
Warachate Khobjai ◽  
◽  
Khemjira Jarmkom ◽  
Nakuntwalai Wisidsri ◽  
Surachai Techaoei

Phytonutrients, also called phytochemicals, are chemicals produced by plants. Foods and vegetables with phytonutrients have antioxidant and anti-inflammatory benefits. The aim of this study was to analyzed 4 parts of 3 lotuses phytochemical constituents by using gas chromatography mass spectrometry. Our results showed that different parts of lotus had a different chemical compound. The major chemical constituents in each extract are 6-Methoxy-2-[p-tolyl]cinchoninic acid (23.92%), Stigmastan-3, 5-diene (6.17%), 5(1H)-Azulenone, 2, 4, 6, 7, 8, 8a-hexahydro-3, 8-dimethyl-4-(1-methylethylidene)-, (8S-cis)- (24.44%), 2-Cyclohexane-1-carboxaldehyde, 2, 6-dimethyl-6-(4-methyl-3-pentennyl (18.15%), Stigmastan-3, 5-diene (24.04%), 2(1H)Naphthalenone, 3, 5, 6, 7, 8, 8a-hexanhydro-4, 8a-dimethyl-6-(1-methylethenyl)-(6.49%), 2-[p-Methoxyphenyl]-8-methylcinchoninic acid (12.98%), Ergosta-4, 6, 22-trien-3, beta, -ol (13.57%), and Stigmastan-3, 5-diene (26.05%). Therefore, Phytonutrients could also provide significant benefits for human’s health that eat plant foods.


2020 ◽  
Vol 981 ◽  
pp. 280-284
Author(s):  
Siti Aisyah Mohamad ◽  
Noor Suhana Adzahar ◽  
Muhammad Nadeem Akhtar ◽  
Seema Zareen ◽  
Thong Chuan Lee

Therapeutic properties of the medicinal plant are due to the presence of phytochemical constituents. The phytochemical constituents of Plumeria alba flower were investigated by phytochemical screening assays and gas chromatography-mass spectrometry (GC-MS). The phytochemical screening of hexane, dichloromethane, ethyl acetate, butanol, and aqueous extracts of P. alba flower showed it contains a various concentration of saponins, flavonoids, tannins, steroids, volatile oil and phenolic compounds. Several major chemical constituents that were identified is squalene, bis(2-ethylhexyl) phthalate, methyl (methyl 4-O-methyl-α-d-mannopyranoside) uronate and tricyclo [7.2.0.0(2,6)] undecan-5-ol, 2,6,10,10-tetramethyl- (isomer 2) by using GC-MS technique.


INDIAN DRUGS ◽  
2018 ◽  
Vol 55 (02) ◽  
pp. 15-19
Author(s):  
J. Aranganayaki ◽  
◽  
G. Jayanthi

In the present study, the hexane: chloroform fraction of Indigofera trita has been subjected to gas chromatography mass spectroscopy (GC-MS) analysis. Thirty phytochemical constituents have been identified. The major chemical constituents are phthalic acid, di(2-propylpentyl) ester, hexadecane, 1-[trans-4-(1-fluoro-2-iodoethyl)cyclohexyl]-trans-4-(3,4-difluorophenyl) cyclohexane, eicosane and 1- methyl-1-(allyloxy)-1-silacopent-3-ene.


2018 ◽  
Vol 4 (1) ◽  
pp. 52-59
Author(s):  
Hesham Hussein Rassem ◽  
Abdurahman Hamid Nour ◽  
Rosli Mohammed Yunus

Gas Chromatography-Mass Spectrometry (GC-MS) the best technique to identified the compounds of essential oils by comparison of mass spectra data obtained from the sample with that taken from pure commercially available standards injected under the same conditions. To characterize the chemical constituents of Hibiscus Flower using GC-MS, the shade dried flower powder was extracted with methanol by using Microwave-assisted Hydrodistillation (MAHD). The GC-MS analysis provided different peaks determining the presence of ten compounds. These compounds havebiological activity namely 2-Phenylthiolane (57.31%), Cyclohexene, 3-ethenyl- (25.91%), Acetaldehyde (12.70%), N-Methylallylamine (9.99%),  ropanamide (6.79%) and Phthalic acid, bis (7-methyloctyl) ester (5.21%). From the results, it can be concluded that Jasmine flower extract shows the presence of 10 phytocompounds. The presence of various bioactive compounds justifies the use of the jasmine flower for various ailments by traditional practitioners.


2020 ◽  
Vol 4 (2) ◽  
pp. 70-74
Author(s):  
Sameer M. Al- Al-Gorany ◽  
Saba Z. AL-Abachi ◽  
Abdulwadood I. Arif ◽  
Entesar E. Aboglida ◽  
Entesar H. Al_Abdeli

For thousands of years plants have been an essential medicinal source with qualities. Empty fruit bunches (EFB) have medicinal values. Ten grams of powdered sample was extracted with 50 mL ethanol overnight and filtered through ash less filter paper, this plant’s ethanol extract has been analyzed using Gas Chromatography–Mass Spectrometry (GC-MS), while the compound mass spectra contained in the extract has been matched with the National Institute of Standards and Technology (NIST) library. The GC-MS analysis provided different peaks determining the presence of eight different phytochemical compounds namely10-Undecenoic acid, Propanoic acid, Cyclopentane acetic acid hydrazide,1,4-Cyclohexanedicarbonitrile.The compounds were identified by comparing their retention time and peak area with literature and by interpreting the mass spectra. Many of them have antioxidant, anti-inflammatory, antimicrobial, antifungal, antitumor, antiviral, anticonvulsant, analgesic and antidiabetic properties.


2021 ◽  
Author(s):  
Innocent U Okagu ◽  
Joseph C Ndefo ◽  
Matthias Onyebuchi Agbo

Newbouldia laevis (P. Beauv.) Seem. (Family, Bignoniaceae), commonly known as tree of life, is a purple-flowering plant that is widely distributed in many parts of Africa. Different parts of the plant, including the leaves, flower, stems and roots are prevalently used in African traditional medicine for the management of many diseases and conditions like diabetes, hypertension, skin diseases, ulcer, tumors, pains, infectious diseases, inflammation, dysentery, sickle cell disease and impotency. This review discusses the trado-medical uses, chemical constituents, and biological activities of N. laevis. Based on information generated from scientific investigations deposited in PubMed and SCOPUS, the chemical constituents of the plant include glycosides, anthraquinolones, volatile oils, tannins, steroids, alkaloids, flavonoids, terpenoids and sterols. Extracts different parts of the plant and compounds isolated from them have been reported to have several health-promoting potentials such as antioxidant, antimalarial, trypanocidal, antimicrobial, anthelmintic, analgesic, anti-inflammatory, antidiabetic, anti-arthritic, anti-thrombotic, cytoprotective, anti-hypertensive, central nervous system modulatory, male reproduction enhancing and oxytocic properties. These scientific investigations have led credence to the ethnobotanical uses of the plant in folkloric practice. In addition, the presence of phytochemical constituents in the plant might be responsible for the wide biological potentials.


Author(s):  
N. H. Shahare ◽  
S. K. Bodele

Dendrophthoe falcata (L.f.) Ettingsh is an important medicinal plant belonging to the family Loranthaceae. It is perennial, climbing and woody parasitic plant of family Loranthaceae. It is ethnomedicinally used for treating ulcers, asthma, impotence, paralysis skin diseases and wounds. In the present study, an attempt was made to investigate the phytochemical constituents present in the Dendrophthoe falcata (L.f.) Ettingsh stem. The preliminary phytochemical screening in different solvents extract was done by using standard methods. The phytochemical screening revealed the presence of carbohydrates, protein and amino acids, fixed oils and fats, saponins, sterols, alkaloids, phenols, tannins, flavonoids, anthocyanin and anthraquinones in different solvent extracts. GC-MS analysis was performed on the methanolic extract to find out the chemical constituents. The GC-MS study revealed the presence of about 51 bioactive compounds. Cyclopentasiloxane, Cyclohexasiloxane, Cycloheptasiloxane, Cyclooctasiloxane, Cyclononasiloxane, Phthalic acid, Hexadecanoic acid, Cyclodecasiloxane, Cyclononasiloxane, Tetracosane, Tetratriacontane, Benzoic acid, 1-Monolinoleoylglycerol trimethylsilyl ether, Octadecane, ç-Sitosterol are some of the major phytoconstituents reported from the sample. Further research work is needed on these identified compounds to analyse their mode of action and usefulness in phytopharmaceutical industries.


2019 ◽  
Vol 30 (3) ◽  
pp. 16-22

World Health Organization (WHO) estimated that 80% of the population of developing countries use traditional medicines, mostly natural plant products, for their primary health care needs. In the past few decades, the medicinal value of plants has been assumed more important dimension owing largely to the discovery that extracts from plants contain not only primary metabolites but also a diverse array of secondary metabolites with antioxidant potential. Medicinal plants are potential sources of natural compounds with biological activities and therefore attract the attention of researchers worldwide. Antioxidants are vital substances which possess ability to protect the body from damage due to free radical-induced oxidative stress. The purpose of current study was to determine the antioxidant activities and bioactive components of Foeniculum vulgare (fennel) (Samonsabar) seeds by using UV Visible Spectrophotometer (UV-Vis) and Gas Chromatography-Mass Spectrometry (GC-MS). Aqueous extract of fennel seeds showed more antioxidant activity (IC50: 0.28 ug/ml) than ethanolic extract (IC50: 0.83 ug/ml) and comparable to standard antioxidant, ascorbic acid (IC50: 0.59 ug/ml). GC-MS analysis was fruitful in identification of compounds based on peak area, retention time, molecular formula, molecular weight, MS Fragmentions and pharmacological actions. Ten bioactive phytochemical compounds from aqueous extracts and 11 from ethanolic extract of fennel seeds were identified. These findings indicated that fennel seeds are potential to provide preventive properties against oxidative damage. These results will give scientific information for quality control of indigenous drug to herbal medicine users and local practitioners using fennel for different types of ailments


Planta Medica ◽  
2021 ◽  
Author(s):  
Garima Agarwal ◽  
Long-Sheng Chang ◽  
Djaja Doel Soejarto ◽  
A. Douglas Kinghorn

AbstractWith about 120 species, Aglaia is one of the largest genera of the plant family Meliaceae (the mahogany plants). It is native to the tropical rainforests of the Indo-Australian region, ranging from India and Sri Lanka eastward to Polynesia and Micronesia. Various Aglaia species have been investigated since the 1960s for their phytochemical constituents and biological properties, with the cyclopenta[b]benzofurans (rocaglates or flavaglines) being of particular interest. Phytochemists, medicinal chemists, and biologists have conducted extensive research in establishing these secondary metabolites as potential lead compounds with antineoplastic and antiviral effects, among others. The varied biological properties of rocaglates can be attributed to their unusual structures and their ability to act as inhibitors of the eukaryotic translation initiation factor 4A (eIF4A), affecting protein translation. The present review provides an update on the recently reported phytochemical constituents of Aglaia species, focusing on rocaglate derivatives. Furthermore, laboratory work performed on investigating the biological activities of these chemical constituents is also covered.


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