The Bacterial Microbiome in Chronic Rhinosinusitis: Richness, Diversity, Postoperative Changes, and Patient Outcomes

2016 ◽  
Vol 30 (1) ◽  
pp. 37-43 ◽  
Author(s):  
Edward John Cleland ◽  
Ahmed Bassiouni ◽  
Sarah Vreugde ◽  
Peter-John Wormald
Keyword(s):  
Chronic Rhinosinusitis ◽  
Patient Outcomes ◽  
Postoperative Changes ◽  
Bacterial Microbiome

The fungal microbiome in chronic rhinosinusitis: richness, diversity, postoperative changes and patient outcomes

2014 ◽  
Vol 4 (4) ◽  
pp. 259-265 ◽  
Author(s):  
Edward John Cleland ◽  
Ahmed Bassioni ◽  
Samuel Boase ◽  
Scot Dowd ◽  
Sarah Vreugde ◽  
...  
Keyword(s):  
Chronic Rhinosinusitis ◽  
Patient Outcomes ◽  
Postoperative Changes ◽  
Fungal Microbiome

scholarly journals Specialized Pro-Resolving Mediator Lipidome and 16S rRNA Bacterial Microbiome Data Associated with Human Chronic Rhinosinusitis

Data in Brief ◽  
2021 ◽  
pp. 107023
Author(s):  
Thad W. Vickery ◽  
Michael Armstrong ◽  
Jennifer M. Kofonow ◽  
Charles E. Robertson ◽  
Miranda E. Kroehl ◽  
...  
Keyword(s):  
16S Rrna ◽  
Chronic Rhinosinusitis ◽  
Bacterial Microbiome ◽  
Microbiome Data

scholarly journals Association of the sinonasal bacterial microbiome with clinical outcomes in chronic rhinosinusitis: a systematic review

2020 ◽  
Vol 10 (4) ◽  
pp. 433-443 ◽  
Author(s):  
James C. Wang ◽  
Charles A. Moore ◽  
Madison V. Epperson ◽  
Ahmad R. Sedaghat
Keyword(s):  
Systematic Review ◽  
Clinical Outcomes ◽  
Chronic Rhinosinusitis ◽  
Bacterial Microbiome

Changes in the bacterial microbiome of patients with chronic rhinosinusitis after endoscopic sinus surgery

2016 ◽  
Vol 7 (1) ◽  
pp. 7-15 ◽  
Author(s):  
Ravi Jain ◽  
Michael Hoggard ◽  
Kristi Biswas ◽  
Melissa Zoing ◽  
Yannan Jiang ◽  
...  
Keyword(s):  
Chronic Rhinosinusitis ◽  
Endoscopic Sinus Surgery ◽  
Sinus Surgery ◽  
Bacterial Microbiome

The effect of medical treatments on the bacterial microbiome in patients with chronic rhinosinusitis: a pilot study

2018 ◽  
Vol 8 (8) ◽  
pp. 890-899 ◽  
Author(s):  
Ravi Jain ◽  
Michael Hoggard ◽  
Melissa Zoing ◽  
Yannan Jiang ◽  
Kristi Biswas ◽  
...  
Keyword(s):  
Pilot Study ◽  
Chronic Rhinosinusitis ◽  
Medical Treatments ◽  
Bacterial Microbiome

scholarly journals Tracking Patient Outcomes Following Foot and Ankle Surgery: The OFAR Experience 2018-2019

2019 ◽  
Vol 4 (4) ◽  
pp. 2473011419S0003
Author(s):  
Kenneth Hunt ◽  
Ross Benthien ◽  
Judith F. Baumhauer ◽  
Christopher DiGiovanni ◽  
Shanthan Challa ◽  
...  
Keyword(s):  
Data Collection ◽  
Patient Outcomes ◽  
Patient Reported Outcomes ◽  
Short Form ◽  
Healthy Population ◽  
Foot And Ankle ◽  
Aggregated Data ◽  
Postoperative Changes ◽  
Patient Reported ◽  
The Impact

Category: Patient Reported Outcomes Introduction/Purpose: Collection and reporting of Patient Reported Outcomes (PROs) has become an integral part of healthcare and healthcare research. In an effort to facilitate AOFAS member participation in secure and efficient patient outcomes data collection, the Orthopaedic Foot and Ankle Outcomes Research (OFAR) Network, a national collaborative surgical outcomes registry, was established in 2018 by and for AOFAS member surgeons and their patients. OFAR aims to collect, aggregate, and report PRO data using the measurement instruments developed by the National Institutes of Health (NIH) Patient Reported Outcomes Measurement Information System (PROMIS). We hypothesize that multiple sites from a variety of health systems can successfully enroll patients into a secure, web-based registry, and that foot and ankle procedures will significantly improve patient reported function and pain. Methods: Since December 2018, seven OFAR pilot sites have been enrolling patients, including three private and four academic practices. Each enrolled patient completed a pre-operative assessment as well as post-operative assessments at 3 time points. Five PROMIS metrics were collected, including Physical Function CAT (PF), Pain Intensity Short Form (PInSF), Pain Interference CAT (PInCAT), Global Health Short Form, and Depression CAT. Pathways, a secure web platform accessible by both patients and providers, was utilized for data collection and storage. The platform also includes a provider dashboard that collects diagnosis, treatment, implant and complication data. The aggregated data was analyzed using Python (v3.6) along with Pandas (v0.23.4). Results: As of December 2018, 877 patients have been enrolled in OFAR. Patients were enrolled from both academic (57%) and private practice (43%) sites. The three most frequently encountered conditions were: ankle impingement, ankle fractures and ankle arthritis. The largest pre- to postoperative changes were seen in the PF and PInCAT scores which significantly improved at 6 months and 12 months for nearly all condition groups (Figure 1). Many of these improvements averaged 20 points on the PROMIS t-score scale, which represents two standard deviations in the PROMIS scoring system, and restored PInCAT and PF to 50 or better, the US healthy population average. There was a trend toward improvement in depression scores for most conditions, with substantial improvement following fracture treatment. Conclusion: We were able to successfully onboard multiple pilot sites, including community private practices without dedicated research resources, to enroll patients in the OFAR platform. Aggregated data demonstrate a significant improvement in PROMIS scores for all conditions treated. The library of information collected is automated, extensive and comprehensive. By aggregating outcomes following treatment by orthopaedic foot and ankle surgeons across practice settings, the OFAR database empowers an unprecedented scrutiny of ‘real world’ patient outcomes and related factors. This facilitates an increasingly granular assessment of the impact of conditions and treatments, enabling patients and providers alike to share in the decision-making process.

Chronic rhinosinusitis: a microbiome in dysbiosis and the search for alternative treatment options

2016 ◽  
Vol 37 (3) ◽  
pp. 149 ◽  
Author(s):  
Amanda Bordin ◽  
Hanna E Sidjabat ◽  
Kyra Cottrell ◽  
Anders Cervin
Keyword(s):  
Chronic Disease ◽  
Chronic Rhinosinusitis ◽  
Alternative Treatment ◽  
Treatment Options ◽  
Current Treatment ◽  
Multifactorial Disease ◽  
Healthy Human ◽  
Common Chronic Disease ◽  
The Future ◽  
Bacterial Microbiome

Chronic rhinosinusitis (CRS) is a common chronic disease. While CRS is a multifactorial disease, many cases involve an imbalance in the sinus bacterial microbiome. This article reviews the composition of the healthy human sinus microbiome compared to the microbiome of CRS patients. Issues with current treatment options, particularly antibiotics, are discussed. Insights into the future of CRS treatment are also explored, principally with regards to probiotics.

scholarly journals Influence of interpersonal traits on patient outcomes in the treatment of chronic rhinosinusitis

2016 ◽  
Vol 7 (4) ◽  
pp. 414-420 ◽  
Author(s):  
Joshua M. Levy ◽  
Jess C. Mace ◽  
Timothy L. Smith ◽  
Zachary M. Soler
Keyword(s):  
Chronic Rhinosinusitis ◽  
Patient Outcomes ◽  
Interpersonal Traits

scholarly journals Asthma onset pattern and patient outcomes in a chronic rhinosinusitis population

2018 ◽  
Vol 8 (4) ◽  
pp. 495-503 ◽  
Author(s):  
Christopher John Staniorski ◽  
Caroline P.E. Price ◽  
Ava R. Weibman ◽  
Kevin C. Welch ◽  
David B. Conley ◽  
...  
Keyword(s):  
Chronic Rhinosinusitis ◽  
Patient Outcomes
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