scholarly journals Super Scan in 68Ga-PSMA Ligand PET/CT in Prostate Cancer-Diagnostic Criteria and Its Significance

2018 ◽  
Vol 3 (1) ◽  
pp. 1-2
Author(s):  
Manas Kumar Sahoo ◽  
2019 ◽  
Vol 103 (1) ◽  
pp. 95-104 ◽  
Author(s):  
Alexander Soldatov ◽  
Christoph A.J. von Klot ◽  
Daniel Walacides ◽  
Thorsten Derlin ◽  
Frank M. Bengel ◽  
...  

2019 ◽  
Vol 46 (11) ◽  
pp. 2289-2297 ◽  
Author(s):  
Ali Afshar-Oromieh ◽  
Bernd Vollnberg ◽  
Ian Alberts ◽  
Alexandrine Bähler ◽  
Christos Sachpekidis ◽  
...  

2013 ◽  
Vol 41 (1) ◽  
pp. 11-20 ◽  
Author(s):  
Ali Afshar-Oromieh ◽  
Christian M. Zechmann ◽  
Anna Malcher ◽  
Matthias Eder ◽  
Michael Eisenhut ◽  
...  

2018 ◽  
Vol 17 (5) ◽  
pp. e2226
Author(s):  
A. Freimanis ◽  
V. Lietuvietis ◽  
E. Vjaters ◽  
L. Roznere ◽  
L. Zemniece ◽  
...  

2017 ◽  
Vol 16 (5) ◽  
pp. e2220 ◽  
Author(s):  
A. Freimanis ◽  
V. Lietuvietis ◽  
V. Skrivelis
Keyword(s):  

Biomedicines ◽  
2020 ◽  
Vol 8 (11) ◽  
pp. 511
Author(s):  
Joachim Brumberg ◽  
Melanie Beckl ◽  
Alexander Dierks ◽  
Andreas Schirbel ◽  
Markus Krebs ◽  
...  

Prostate-specific membrane antigen (PSMA) ligand PET/CT enables the localization of tumor lesions in patients with recurrent prostate cancer, but it is unclear whether androgen deprivation therapy (ADT) influences diagnostic accuracy. The aim of this study was to evaluate the effect of ADT on the detection rate of 68Ga-PSMA ligand PET/CT. Thus, 399 patients with initial radical prostatectomy and 68Ga-PSMA ligand PET/CT during PSA relapse were retrospectively evaluated. Propensity score matching was used to create two balanced groups of 62 subjects who either did or did not receive ADT within six months before imaging. All 68Ga-PSMA ligand PET/CT were evaluated visually and with semiquantitative measures. The detection rate of tumor recurrence was significantly higher in the group with ADT (88.7% vs. 72.6%, p = 0.02) and improved with increasing PSA-levels in both groups. In subjects with pathological PET/CT and ADT, whole-body total lesion PSMA (p < 0.01) and PSMA-derived tumor volume (p < 0.01) were significantly higher than in those without ADT. More PSMA-positive lesions and higher PSMA-derived volumetric parameters in patients with ADT suggest that a better detection rate is related to a (biologically) more advanced disease stage. Due to high detection rates in patients with PSA-levels < 2 ng/mL, the withdrawal of ADT before PSMA ligand PET/CT cannot be recommended.


2019 ◽  
Vol 44 (7) ◽  
pp. 2545-2556 ◽  
Author(s):  
Mohammad Abd Alkhalik Basha ◽  
Maged Abdel Galil Hamed ◽  
Omar Hussein ◽  
Tarek El-Diasty ◽  
Yasser Ibrahim Abdelkhalek ◽  
...  

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