scholarly journals The experimental study of the antihypoxic and antioxidant activity of 5,7-dihydro-1H-pyrrolo-[2,3-d]pyrimidine derivatives

2017 ◽  
Vol 0 (3(91)) ◽  
pp. 61-65
Author(s):  
V. A. Volkovoy ◽  
O. V. Sevrukov ◽  
S. V. Kolisnyk ◽  
N. V. Derkach ◽  
S. I. Kryzhna ◽  
...  
Keyword(s):  
Experimental Study ◽  
Antioxidant Activity ◽  
Pyrimidine Derivatives

ChemInform Abstract: Synthesis and Antioxidant Activity of 1,3,4-Oxadiazole Tagged Thieno[2,3-d]pyrimidine Derivatives.

ChemInform ◽  
2013 ◽  
Vol 44 (16) ◽  
pp. no-no
Author(s):  
Y. Kotaiah ◽  
N. Harikrishna ◽  
K. Nagaraju ◽  
C. Venkata Rao
Keyword(s):  
Antioxidant Activity ◽  
Pyrimidine Derivatives

Synthesis and Antioxidant Activity of New Pyrazolo[1,5-a]Pyrimidine Derivatives Incorporating a Thiazol-2-yldiazenyl Moiety

2015 ◽  
Vol 53 (6) ◽  
pp. 1820-1826 ◽  
Author(s):  
Ahmed El-Mekabaty ◽  
Osman M. O. Habib ◽  
Evelin B. Moawad ◽  
Ali M. Hasel
Keyword(s):  
Antioxidant Activity ◽  
Pyrimidine Derivatives

TiO2 -SiO2 Catalyzed Eco-friendly Synthesis and Antioxidant Activity of Benzopyrano[2,3-d ]pyrimidine Derivatives

2017 ◽  
Vol 54 (5) ◽  
pp. 2598-2604 ◽  
Author(s):  
Shaik Ahammed Kabeer ◽  
Gajjala Raghavendra Reddy ◽  
Poola Sreelakshmi ◽  
Darla Mark Manidhar ◽  
Cirandur Suresh Reddy
Keyword(s):  
Antioxidant Activity ◽  
Pyrimidine Derivatives

Synthesis, X-ray, spectroscopic characterization, DFT and antioxidant activity of 1,2,4-triazolo[1,5-a]pyrimidine derivatives

2019 ◽  
Vol 1177 ◽  
pp. 131-142 ◽  
Author(s):  
Sanae Lahmidi ◽  
El Hassane Anouar ◽  
Mohamed El Hafi ◽  
Mohammed Boulhaoua ◽  
Abdelaziz Ejjoummany ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Spectroscopic Characterization ◽  
Pyrimidine Derivatives ◽  
X Ray

scholarly journals In water multicomponent synthesis of low-molecular-mass 4,7-dihydrotetrazolo[1,5-a]pyrimidines

2019 ◽  
Vol 15 ◽  
pp. 2390-2397 ◽  
Author(s):  
Irina G Tkachenko ◽  
Sergey A Komykhov ◽  
Vladimir I Musatov ◽  
Svitlana V Shishkina ◽  
Viktoriya V Dyakonenko ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Microwave Irradiation ◽  
Molecular Mass ◽  
Acetoacetic Ester ◽  
Analogous Reaction ◽  
Multicomponent Synthesis ◽  
Pyrimidine Derivatives ◽  
Aliphatic Aldehydes ◽  
Three Component Reaction ◽  
Selective Formation

The three-component reaction of 5-aminotetrazole with aliphatic aldehydes (formaldehyde, acetaldehyde) and acetoacetic ester derivatives in water under microwave irradiation leads to the selective formation of 4,7-dihydrotetrazolo[1,5-a]pyrimidine derivatives. Under similar conditions using 4,4,4-trifluoroacetoacetic ester 5-hydroxy-4,5,6,7-tetrahydrotetrazolo[1,5-a]pyrimidines are obtained. The analogous reaction with acetylacetone requires scandium(III) triflate as catalyst. The antioxidant activity of selected compounds was assayed with 1,1-diphenyl-2-picrylhydrazyl.

Synthesis and antioxidant activity of 1,3,4-oxadiazole tagged thieno[2,3-d]pyrimidine derivatives

2012 ◽  
Vol 58 ◽  
pp. 340-345 ◽  
Author(s):  
Y. Kotaiah ◽  
N. Harikrishna ◽  
K. Nagaraju ◽  
C. Venkata Rao
Keyword(s):  
Antioxidant Activity ◽  
Pyrimidine Derivatives

scholarly journals Synthesis, Cytotoxicity, Xanthine Oxidase Inhibition, Antioxidant of New Pyrazolo{3,4 d}Pyrimidine Derivatives

2019 ◽  
Vol 16 (4(Suppl.)) ◽  
pp. 1003
Author(s):  
Khammas Et al.
Keyword(s):  
Antioxidant Activity ◽  
Physical Properties ◽  
Xanthine Oxidase ◽  
Potassium Carbonate ◽  
Pyrimidine Derivatives ◽  
Azo Compound ◽  
Dimethyl Amine ◽  
Oxidase Inhibition ◽  
Ft Ir ◽  
Xanthine Oxidase Inhibition

         Allopurinol derivative were prepared by reacting the (1-chloroacetyl)-2-Hydropyrazolo{3,4-d}pyrimidine-4-oneiwith 5- methoxy- 2-aminoibenzothiazoleiunder certain conditions to obtain new compound  ( N- (2-aminoacetyl (5-methoxy) benzothiazole -2yl) (A4), Reaction of 5-(P-dimethyl amine benzene)-2-amino-1,3,4- oxadiazole in the presence of potassium carbonate anhydrous to yield new  compound (N-(2- aminoacetyl-5-(P-dimethyl amine benzene )-1,3,4-oxadiazoles-2-yl)(A30) and Azo compound (N-(5-(Azo-2-hydroxy-5-amino benzene)-1,3-Diazol-2yl)Allopurinol(A46). The structure of prepared compounds were confirmed by (FT-IR) technique and their physical properties. The synthesized compounds were tested for cytotoxicity, Xanthine oxidase inhibition, and antioxidant activity.

scholarly journals UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL SPONS (Mycale vansoesti Sensu) YANG DIKOLEKSI DARI KEPULAUAN MANTEHAGE

PHARMACON ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 812
Author(s):  
Stela Mahdalena Lampongajo ◽  
Adithya Yudistira ◽  
Erladys Rumondor
Keyword(s):  
Experimental Study ◽  
Antioxidant Activity ◽  
Pharmaceutical Industry ◽  
Ethanol Extract ◽  
Added Value ◽  
Antioxidant Content

ABSTRACTMycale sponges have potential as antioxidants. Mycale vansoesti Sensu is one of the dominant sponges in the Mantehage Islands, Manado. This study is a laboratory experimental study with the ethanol extract of Mycale Vansoesti Sensu sponge with the DPPH [1,1-diphenyl-2-picrylhydrazyl] method to analyze antioxidant activity using a spectrophotometer. The results of this study show that the antioxidant levels of the Mycale vansoesti Sensu Sponge in the waters of the island of Mantehage have antioxidant activity and the higher the concentration the higher the antioxidant content produced. The greatest antioxidant content is found in the Mycale vansoesti Sensu Sponge with a concentration of 0,35 mg / L. This shows that the extract of the Mycale vansosti Sensu sponge has vital potential as an antioxidant that provides added value in the pharmaceutical industry. Keywords: Antioxidant, DPPH, Mycale vansoesti Sensu, Mantehage Island.  ABSTRAKSpons genus Mycale terdapat potensi sebagai antioksidan. Mycale vansoesti Sensu merupakan salah satu jenis spons yang cukup dominan dikepulauan Mantehage, Manado. Penelitian ini merupakan eksperimental laboratorium dengan pengujian terhadap ektrak etanol spons Mycale Vansoesti Sensu dengan metode DPPH [1,1-difenil-2-pikrilhidrazil] untuk menganalisis aktivitas antioksidan dengan menggunakan spektrofotometer. Hasil penelitian ini memperlihatkan kadar antioksidan dari Spons Mycale vansoesti Sensu di perairan pulau Mantehage mempunyai aktivitas antioksidan dan semakin tinggi konsentrasi semakin tinggi pula kadar antioksidan yang dihasilkan. Kadar antioksidan yang paling besar terdapat pada Spons Mycale vansoesti Sensu dengan konsentrasi 0,35 mg/L. Hal ini menunjukkan bahwa ekstrak spons Mycale vansosti Sensu memiliki potensi vital sebagai antioksidan yang memberikan nilai tambah dalam industri farmasi. Kata kunci : Antioksidan, DPPH, Mycale vansoesti Sensu, pulau Mantehage.

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