Central Yunnan lead-zinc polymetallic province in Sichuan-Yunnan-Guizhou metallogenic province has 50 large, medium and small acale of pb-zn deposits. Through contrast research, ore-bearing rock is developed from Kunyang group of Early Proterozoic to Triassic carbonate, ore body, which is characterized by low temperature and low salinity, is obviously controlled by faults, and is accompanied by a strong dolomitization and calciization. Possiblly, metallogenic epoch is Mesozonic. The ore-forming material mainly comes from strata itself, lesser from magmatic rocks. Underground thermal water is the main mineralized hydrothermal water.